1EKX
THE ISOLATED, UNREGULATED CATALYTIC TRIMER OF ASPARTATE TRANSCARBAMOYLASE COMPLEXED WITH BISUBSTRATE ANALOG PALA (N-(PHOSPHONACETYL)-L-ASPARTATE)
Summary for 1EKX
| Entry DOI | 10.2210/pdb1ekx/pdb |
| Related | 3CSU |
| Descriptor | ASPARTATE TRANSCARBAMOYLASE, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, CALCIUM ION, ... (4 entities in total) |
| Functional Keywords | atcase catalytic subunit, bisubstrate analog complex, transferase |
| Biological source | Escherichia coli |
| Total number of polymer chains | 3 |
| Total formula weight | 104250.42 |
| Authors | Endrizzi, J.A.,Beernink, P.T.,Alber, T.,Schachman, H.K. (deposition date: 2000-03-09, release date: 2000-05-12, Last modification date: 2024-02-07) |
| Primary citation | Endrizzi, J.A.,Beernink, P.T.,Alber, T.,Schachman, H.K. Binding of bisubstrate analog promotes large structural changes in the unregulated catalytic trimer of aspartate transcarbamoylase: implications for allosteric regulation induced cell migration. Proc.Natl.Acad.Sci.USA, 97:5077-5082, 2000 Cited by PubMed: 10805770DOI: 10.1073/pnas.090087197 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.95 Å) |
Structure validation
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