3ORI

Mycobacterium tuberculosis PknB kinase domain L33D mutant (crystal form 1)

Summary for 3ORI

• Entry DOI: 10.2210/pdb3ori/pdb
• Related: 1mru 1o6y 3f61 3f69 3ORK 3ORL 3ORM 3ORO 3ORP 3ORT
• Descriptor: Serine/threonine protein kinase, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, MANGANESE (II) ION, ... (4 entities in total)
• Functional Keywords: structural genomics, tb structural genomics consortium, tbsgc, kinase, signal transduction, transferase
• Biological source: Mycobacterium tuberculosis
• Total number of polymer chains: 4
• Total formula weight: 136614.91

Authors

Lombana, T.N.,Echols, N.,Good, M.C.,Thomsen, N.D.,Ng, H.-L.,Alber, T.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2010-09-07, release date: 2010-12-15, Last modification date: 2023-09-06)

• Primary citation: Lombana, T.N.,Echols, N.,Good, M.C.,Thomsen, N.D.,Ng, H.L.,Greenstein, A.E.,Falick, A.M.,King, D.S.,Alber, T.; Allosteric activation mechanism of the Mycobacterium tuberculosis receptor Ser/Thr protein kinase, PknB.; Structure, 18:1667-1677, 2010; PubMed: 21134645; DOI: 10.1016/j.str.2010.09.019

Experimental method

X-RAY DIFFRACTION (2 Å)