3STQ
 
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8ZUE
 | | cryo-electron microscopy (cryo-EM) structure of the Hachiman defense system from Escherichia coli | | Descriptor: | Anti-bacteriophage protein A, Anti-bacteriophage protein B | | Authors: | Cui, Y.Q, Dai, Z.K, Ouyang, Y.F, Wang, Y.J, Guan, Z.Y, Zou, T.T. | | Deposit date: | 2024-06-08 | | Release date: | 2025-03-26 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Bacterial Hachiman complex executes DNA cleavage for antiphage defense.
Nat Commun, 16, 2025
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6JG5
 | | Crystal structure of AimR | | Descriptor: | AimR transcriptional regulator | | Authors: | Guan, Z.Y, Pei, K, Zou, T.T. | | Deposit date: | 2019-02-13 | | Release date: | 2019-07-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.221 Å) | | Cite: | Structural insights into DNA recognition by AimR of the arbitrium communication system in the SPbeta phage.
Cell Discov, 5, 2019
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6JG9
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6JG8
 | | Crystal structure of AimR in complex with DNA | | Descriptor: | AimR transcriptional regulator, DNA (31-MER) | | Authors: | Guan, Z.Y, Pei, K, Zou, T.T. | | Deposit date: | 2019-02-13 | | Release date: | 2019-07-03 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.097 Å) | | Cite: | Structural insights into DNA recognition by AimR of the arbitrium communication system in the SPbeta phage.
Cell Discov, 5, 2019
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8ZNJ
 | | Cryo-EM structure of a short prokaryotic Argonaute system from archaeon Suldolobus islandicus | | Descriptor: | DNA (5'-D(*CP*CP*TP*CP*CP*AP*GP*GP*GP*TP*AP*TP*CP*TP*AP*AP*GP*CP*TP*TP*TP*GP*AP*A)-3'), MAGNESIUM ION, Piwi domain-containing protein, ... | | Authors: | Dai, Z.K, Guan, Z.Y, Han, W.Y, Zou, T.T. | | Deposit date: | 2024-05-27 | | Release date: | 2025-02-19 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | Structural and mechanistic insights into the activation of a short prokaryotic argonaute system from archaeon Sulfolobus islandicus.
Nucleic Acids Res., 53, 2025
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9LGW
 | | Cryo-EM structure of SiAgo-Aga1 complex | | Descriptor: | Piwi domain-containing protein, SiAgo-associated protein1, SiAga1 | | Authors: | Dai, Z.K, Guan, Z.Y, Zou, T.T. | | Deposit date: | 2025-01-10 | | Release date: | 2025-02-19 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | Structural and mechanistic insights into the activation of a short prokaryotic argonaute system from archaeon Sulfolobus islandicus.
Nucleic Acids Res., 53, 2025
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9JM0
 | | retron Ec86-effector fiber | | Descriptor: | DNA (85-MER), NICOTINAMIDE, RNA (5'-R(P*CP*GP*UP*AP*AP*GP*GP*GP*UP*GP*CP*GP*CP*A)-3'), ... | | Authors: | Wang, Y.J, Guan, Z.Y, Wang, C, Zou, T.T. | | Deposit date: | 2024-09-20 | | Release date: | 2024-12-18 | | Method: | ELECTRON MICROSCOPY (2.7 Å) | | Cite: | DNA methylation activates retron Ec86 filaments for antiphage defense.
Cell Rep, 43, 2024
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5XYB
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5Y24
 | | Crystal structure of AimR from Bacillus phage SPbeta in complex with its signalling peptide | | Descriptor: | AimR transcriptional regulator, BROMIDE ION, GLY-MET-PRO-ARG-GLY-ALA | | Authors: | Wang, Q, Guan, Z.Y, Zou, T.T, Yin, P. | | Deposit date: | 2017-07-24 | | Release date: | 2018-09-19 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (1.922 Å) | | Cite: | Structural basis of the arbitrium peptide-AimR communication system in the phage lysis-lysogeny decision.
Nat Microbiol, 3, 2018
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5GMQ
 | | Structure of MERS-CoV RBD in complex with a fully human antibody MCA1 | | Descriptor: | 1,2-ETHANEDIOL, MCA1 heavy chain, MCA1 light chain, ... | | Authors: | Chen, C, Wang, J.M, Zou, T.T, Gao, X.P, Cui, S, Jin, Q. | | Deposit date: | 2016-07-15 | | Release date: | 2017-05-31 | | Last modified: | 2024-11-20 | | Method: | X-RAY DIFFRACTION (2.703 Å) | | Cite: | Human Neutralizing Monoclonal Antibody Inhibition of Middle East Respiratory Syndrome Coronavirus Replication in the Common Marmoset.
J. Infect. Dis., 215, 2017
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5YEJ
 | | Crystal structure of BioQ with its naturel double-stranded DNA operator | | Descriptor: | DNA (5'-D(*AP*CP*CP*TP*GP*AP*AP*CP*AP*CP*CP*GP*TP*TP*CP*AP*AP*GP*T)-3'), DNA (5'-D(*AP*CP*TP*TP*GP*AP*AP*CP*GP*GP*TP*GP*TP*TP*CP*AP*GP*GP*T)-3'), TetR family transcriptional regulator | | Authors: | Yan, L, Guan, Z.Y, Zou, T.T. | | Deposit date: | 2017-09-17 | | Release date: | 2018-09-26 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.698 Å) | | Cite: | Structural insights into operator recognition by BioQ in the Mycobacterium smegmatis biotin synthesis pathway.
Biochim Biophys Acta Gen Subj, 1862, 2018
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5YEK
 | | Crystal structure of BioQ | | Descriptor: | TetR family transcriptional regulator | | Authors: | Yan, L, Guan, Z.Y, Zou, T.T. | | Deposit date: | 2017-09-17 | | Release date: | 2018-09-26 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.191 Å) | | Cite: | Structural insights into operator recognition by BioQ in the Mycobacterium smegmatis biotin synthesis pathway.
Biochim Biophys Acta Gen Subj, 1862, 2018
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5YGU
 | | Crystal structure of Escherichia coli (strain K12) mRNA Decapping Complex RppH-DapF | | Descriptor: | Diaminopimelate epimerase, IODIDE ION, L(+)-TARTARIC ACID, ... | | Authors: | Wang, Q, Guan, Z.Y, Zhang, D.L, Zou, T.T, Yin, P. | | Deposit date: | 2017-09-27 | | Release date: | 2018-06-06 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.298 Å) | | Cite: | DapF stabilizes the substrate-favoring conformation of RppH to stimulate its RNA-pyrophosphohydrolase activity in Escherichia coli.
Nucleic Acids Res., 46, 2018
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7XJG
 | | Cryo-EM structure of E.coli retron-Ec86 in complex with its effector at 2.5 angstrom | | Descriptor: | DNA (105-MER), MAGNESIUM ION, RNA (14-MER), ... | | Authors: | Wang, Y.J, Guan, Z.Y, Zou, T.T. | | Deposit date: | 2022-04-17 | | Release date: | 2022-09-14 | | Last modified: | 2024-07-03 | | Method: | ELECTRON MICROSCOPY (2.51 Å) | | Cite: | Cryo-EM structures of Escherichia coli Ec86 retron complexes reveal architecture and defence mechanism.
Nat Microbiol, 7, 2022
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7FCT
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7V9U
 | | Cryo-EM structure of E.coli retron-Ec86 (RT-msDNA-RNA) at 3.2 angstrom | | Descriptor: | DNA (105-MER), RNA (5'-R(P*CP*GP*UP*AP*AP*GP*GP*G)-3'), RNA (81-MER), ... | | Authors: | Wang, Y.J, Guan, Z.Y, Zou, T.T. | | Deposit date: | 2021-08-26 | | Release date: | 2022-08-31 | | Last modified: | 2024-06-19 | | Method: | ELECTRON MICROSCOPY (3.12 Å) | | Cite: | Cryo-EM structures of Escherichia coli Ec86 retron complexes reveal architecture and defence mechanism.
Nat Microbiol, 7, 2022
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7V9X
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