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PDB: 38 件

6EBA
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BU of 6eba by Molmil
Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in Inward-facing And Unoccupied Conformation
分子名称: Major facilitator family transporter
著者Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y.
登録日2018-08-06
公開日2019-08-21
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.812 Å)
主引用文献Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
Sci Bull (Beijing), 64, 2019
6E8J
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BU of 6e8j by Molmil
Crystal Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster, in Inward-facing And Occupied Conformation
分子名称: Major facilitator family transporter
著者Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y.
登録日2018-07-30
公開日2019-08-14
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (3.091 Å)
主引用文献Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
Sci Bull (Beijing), 64, 2019
6E9C
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BU of 6e9c by Molmil
Selenomethionine Derivative Structure of A Bacterial Homolog to Human Lysosomal Transporter, Spinster
分子名称: Major facilitator family transporter
著者Zhou, F, Yao, D, Rao, B, Zhang, L, Cao, Y.
登録日2018-07-31
公開日2019-08-14
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Crystal structure of a bacterial homolog to human lysosomal transporter, spinster
Sci Bull (Beijing), 64, 2019
7CZ5
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BU of 7cz5 by Molmil
Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex
分子名称: CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M.
登録日2020-09-07
公開日2020-11-18
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Structural basis for activation of the growth hormone-releasing hormone receptor.
Nat Commun, 11, 2020
5Z33
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BU of 5z33 by Molmil
Crystal structure of Mitogen-activated Protein Kinase Mps1 in Magnaporthe oryzae
分子名称: Mitogen-activated protein kinase
著者Zhou, F, Liu, J.F, Zhang, G.Z.
登録日2018-01-05
公開日2019-03-20
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structure of Mitogen-activated Protein Kinase Mps1 in Magnaporthe oryzae
To Be Published
7DW9
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BU of 7dw9 by Molmil
Cryo-EM structure of human V2 vasopressin receptor in complex with an Gs protein
分子名称: CHOLESTEROL, CYS-TYR-PHE-GLN-ASN-CYS-PRO-ARG-GLY-NH2, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ...
著者Zhou, F, Jiang, Y.
登録日2021-01-15
公開日2021-07-21
最終更新日2022-02-16
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular basis of ligand recognition and activation of human V2 vasopressin receptor.
Cell Res., 31, 2021
5KLV
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BU of 5klv by Molmil
Structure of bos taurus cytochrome bc1 with fenamidone inhibited
分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-5-methyl-2-(methylsulfanyl)-5-phenyl-3-(phenylamino)-3,5-dihydro-4H-imidazol-4-one, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ...
著者Xia, D, Esser, L, Zhou, F, Zhou, Y, Xiao, Y, Tang, W.K, Yu, C.A, Qin, Z.
登録日2016-06-25
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.652 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
5KO2
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BU of 5ko2 by Molmil
Mouse pgp 34 linker deleted mutant Hg derivative
分子名称: MERCURY (II) ION, Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-06-29
公開日2016-11-30
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KLI
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BU of 5kli by Molmil
Rhodobacter sphaeroides bc1 with stigmatellin and antimycin
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, (2R,3S,6S,7R,8R)-3-{[3-(FORMYLAMINO)-2-HYDROXYBENZOYL]AMINO}-8-HEXYL-2,6-DIMETHYL-4,9-DIOXO-1,5-DIOXONAN-7-YL (2S)-2-METHYLBUTANOATE, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-24
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.996 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
5KOY
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BU of 5koy by Molmil
Mouse pgp 34 linker deleted bound with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-01
公開日2016-12-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KPD
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BU of 5kpd by Molmil
Mouse pgp 34 linker deleted double EQ mutant
分子名称: Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-03
公開日2016-11-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KPI
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BU of 5kpi by Molmil
Mouse native PGP
分子名称: Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-04
公開日2016-11-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (4.01 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KPJ
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BU of 5kpj by Molmil
Mouse pgp methylated protein
分子名称: Multidrug resistance protein 1A
著者Xia, D, Esser, L, Zhou, F.
登録日2016-07-04
公開日2016-11-30
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity.
J. Biol. Chem., 292, 2017
5KKZ
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BU of 5kkz by Molmil
Rhodobacter sphaeroides bc1 with famoxadone
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, ASCORBIC ACID, Cytochrome b, ...
著者Xia, D, Esser, L, Zhou, F, Tang, W.K, Yu, C.A.
登録日2016-06-23
公開日2016-10-12
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.97 Å)
主引用文献Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III.
J.Biol.Chem., 291, 2016
6KXW
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BU of 6kxw by Molmil
Crystal structure of human aquaporin AQP7 in bound to glycerol
分子名称: Aquaporin-7, GLYCEROL
著者Zhang, L, Yao, D, Zhou, F, Zhang, Q, Zhou, L, Cao, Y.
登録日2019-09-13
公開日2019-11-27
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献The structural basis for glycerol permeation by human AQP7
Sci Bull (Beijing), 66, 2020
7TAY
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BU of 7tay by Molmil
Bos Taurus Mitochondrial BC1 in complex with Pyramoxadone
分子名称: (2R)-3-{[(S)-(2-aminoethoxy)(hydroxy)phosphoryl]oxy}-2-(tetradecanoyloxy)propyl octadecanoate, (5S)-3-anilino-5-methyl-5-(6-phenoxypyridin-3-yl)-1,3-oxazolidine-2,4-dione, 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, ...
著者Xia, D, Zhou, F, Esser, L.
登録日2021-12-21
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Conformation Switch of Rieske ISP subunit is revealed by the Crystal Structure of Bacterial Cytochrome bc1 in Complex with Azoxystrobin
to be published
7TCE
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BU of 7tce by Molmil
Crystal structure of delta sub IV Rhodobacter Sphaeroides bc1 with the antimalarial drug atovaquone.
分子名称: 1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOETHANOLAMINE, 2-[trans-4-(4-chlorophenyl)cyclohexyl]-3-hydroxynaphthalene-1,4-dione, Cytochrome b, ...
著者Esser, L, Xia, D, Zhou, F.
登録日2021-12-23
公開日2023-01-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献Crystal structure of delta sub IV Rhodobacter Sphaeroides bc1 with the antimalarial drug atovaquone.
To Be Published
7TLJ
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BU of 7tlj by Molmil
Rhodobacter sphaeroides Mitochondrial respiratory chain complex
分子名称: (1R)-2-{[(R)-(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(DODECANOYLOXY)METHYL]ETHYL (9Z)-OCTADEC-9-ENOATE, (5S)-3-anilino-5-methyl-5-(6-phenoxypyridin-3-yl)-1,3-oxazolidine-2,4-dione, 14 kDa peptide of ubiquinol-cytochrome c2 oxidoreductase complex, ...
著者Xia, D, Zhou, F, Esser, L, Huang, R.
登録日2022-01-18
公開日2023-02-08
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献Conformation Switch of Rieske ISP subunit is revealed by the Crystal Structure of Bacterial Cytochrome bc1 in Complex with Azoxystrobin
to be published
7TZ6
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BU of 7tz6 by Molmil
Structure of mitochondrial bc1 in complex with ck-2-68
分子名称: 7-chloranyl-3-methyl-2-[4-[[4-(trifluoromethyloxy)phenyl]methyl]phenyl]-1~{H}-quinolin-4-one, Cytochrome b, Cytochrome b-c1 complex subunit 1, ...
著者Xia, D, Esser, L, Zhou, F, Huang, R.
登録日2022-02-15
公開日2023-02-22
最終更新日2023-09-06
実験手法ELECTRON MICROSCOPY (2.88 Å)
主引用文献Structure of complex III with bound antimalarial agent CK-2-68 provides insights into selective inhibition of Plasmodium cytochrome bc 1 complexes.
J.Biol.Chem., 299, 2023
8DOK
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BU of 8dok by Molmil
Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer in complex with 8ANC195 and 10-1074
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Chen, Y, Zhou, F, Huang, R, Tolbert, W, Pazgier, M.
登録日2022-07-13
公開日2023-07-19
最終更新日2023-11-08
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Nat Commun, 14, 2023
8G6U
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BU of 8g6u by Molmil
Cryo-EM structure of T/F100 SOSIP.664 HIV-1 Env trimer with LMHS mutations in complex with 8ANC195 and 10-1074
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CRF-1_AE T/F100 HIV-1 gp41, ...
著者Chen, Y, Zhou, F, Huang, R, Tolbert, W, Pazgier, M.
登録日2023-02-16
公開日2023-11-08
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Structure-function analyses reveal key molecular determinants of HIV-1 CRF01_AE resistance to the entry inhibitor temsavir.
Nat Commun, 14, 2023
2FCI
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BU of 2fci by Molmil
Structural basis for the requirement of two phosphotyrosines in signaling mediated by Syk tyrosine kinase
分子名称: C-termainl SH2 domain from phospholipase C-gamma-1 comprising residues 663-759, Doubly phosphorylated peptide derived from Syk kinase comprising residues 338-350
著者Groesch, T.D, Zhou, F, Mattila, S, Geahlen, R.L, Post, C.B.
登録日2005-12-12
公開日2006-01-31
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by syk tyrosine kinase
J.Mol.Biol., 356, 2006
6AHZ
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BU of 6ahz by Molmil
The NMR Structure of the Polysialyltranseferase Domain (PSTD) in Polysialyltransferase ST8siaIV
分子名称: CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase
著者Liu, X.H, Lu, B, Peng, L.X, Liao, S.M, Zhou, F, Chen, D, Lu, Z.L, Zhou, G.P, Huang, R.B.
登録日2018-08-21
公開日2018-10-24
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献The Inhibition of Polysialyltranseferase ST8SiaIV Through Heparin Binding to Polysialyltransferase Domain (PSTD).
Med Chem, 15, 2019
8TUL
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BU of 8tul by Molmil
Cryo-EM structure of the human MRS2 magnesium channel under Mg2+ condition
分子名称: MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial
著者Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D.
登録日2023-08-16
公開日2023-09-13
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023
8TUP
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BU of 8tup by Molmil
Cryo-EM structure of the human MRS2 magnesium channel under Mg2+-free condition
分子名称: MAGNESIUM ION, Magnesium transporter MRS2 homolog, mitochondrial
著者Lai, L.T.F, Balaraman, J, Zhou, F, Matthies, D.
登録日2023-08-16
公開日2023-09-13
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Cryo-EM structures of human magnesium channel MRS2 reveal gating and regulatory mechanisms.
Nat Commun, 14, 2023

 

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