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PDB: 85 件

5W5F
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BU of 5w5f by Molmil
Cryo-EM structure of the T4 tail tube
分子名称: Tail tube protein gp19
著者Zheng, W, Wang, F, Taylor, N.M, Guerrero-Ferreira, R.C, Leiman, P.G, Egelman, E.H.
登録日2017-06-15
公開日2017-08-16
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Refined Cryo-EM Structure of the T4 Tail Tube: Exploring the Lowest Dose Limit.
Structure, 25, 2017
8TJ2
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BU of 8tj2 by Molmil
CryoEM structure of Myxococcus xanthus type IV pilus
分子名称: Type IV major pilin protein PilA
著者Zheng, W, Egelman, E.H.
登録日2023-07-20
公開日2023-08-09
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Tight-packing of large pilin subunits provides distinct structural and mechanical properties for the Myxococcus xanthus type IVa pilus.
Proc.Natl.Acad.Sci.USA, 121, 2024
7DMP
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BU of 7dmp by Molmil
Mouse radial spoke complex
分子名称: Radial spoke head 1 homolog, Radial spoke head protein 4 homolog A, Radial spoke head protein 9 homolog
著者Zheng, W, Cong, Y.
登録日2020-12-05
公開日2021-07-21
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Distinct architecture and composition of mouse axonemal radial spoke head revealed by cryo-EM
Proc.Natl.Acad.Sci.USA, 118, 2021
5F1M
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BU of 5f1m by Molmil
Crystal structure of Serine/threonine phosphatase Stp1 from Staphylococcus aureus
分子名称: MANGANESE (II) ION, Phosphorylated protein phosphatase
著者Zheng, W.H, Wang, T, Li, Z.G.
登録日2015-11-30
公開日2016-08-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.322 Å)
主引用文献Structure-Based Identification of a Potent Inhibitor Targeting Stp1-Mediated Virulence Regulation in Staphylococcus aureus
Cell Chem Biol, 23, 2016
6OIF
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BU of 6oif by Molmil
Cryo-EM structure of human TorsinA filament
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Torsin-1A
著者Zheng, W, Demircioglu, F.E, Schwartz, T.U, Egelman, E.H.
登録日2019-04-09
公開日2019-07-24
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献The AAA + ATPase TorsinA polymerizes into hollow helical tubes with 8.5 subunits per turn.
Nat Commun, 10, 2019
6MKS
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BU of 6mks by Molmil
Cryo-EM structure of NLRC4-CARD filament
分子名称: Chimera protein of NLR family CARD domain-containing protein 4 and EGFP
著者Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
登録日2018-09-26
公開日2018-11-07
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryo-EM structure of the NLRC4CARDfilament provides insights into how symmetric and asymmetric supramolecular structures drive inflammasome assembly.
J. Biol. Chem., 293, 2018
6C53
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BU of 6c53 by Molmil
Cryo-EM structure of the Type 1 pilus rod
分子名称: Type-1 fimbrial protein, A chain
著者Zheng, W, Wang, F, Luna-Rico, A, Francetic, O, Hultgren, S.J, Egelman, E.H.
登録日2018-01-13
公開日2018-01-31
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions.
Elife, 7, 2018
7JSV
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BU of 7jsv by Molmil
Cryo-EM structure of conjugative pili from carbapenem-resistant Klebsiella pneumoniae
分子名称: 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, Pilin
著者Zheng, W, Pena, A, Frankel, G, Egelman, E.H.
登録日2020-08-16
公開日2020-09-02
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Cryoelectron-Microscopic Structure of the pKpQIL Conjugative Pili from Carbapenem-Resistant Klebsiella pneumoniae.
Structure, 28, 2020
6NRV
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BU of 6nrv by Molmil
Cryo-EM reconstruction of CFA/I pili
分子名称: CFA/I fimbrial subunit B
著者Zheng, W, Andersson, M, Bullitt, E, Egelman, E.H.
登録日2019-01-24
公開日2019-09-11
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Cryo-EM structure of the CFA/I pilus rod.
Iucrj, 6, 2019
7KHW
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BU of 7khw by Molmil
Cryo-EM structure of enteropathogenic Escherichia coli type III secretion system EspA filament
分子名称: Translocon EspA
著者Zheng, W, Ilangovan, A, Costa, T.R.D, Egelman, E.H.
登録日2020-10-22
公開日2020-12-23
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Cryoelectron-microscopy structure of the enteropathogenic Escherichia coli type III secretion system EspA filament.
Proc.Natl.Acad.Sci.USA, 118, 2021
6D1W
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BU of 6d1w by Molmil
human PKD2 F604P mutant
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Polycystin-2
著者Zheng, W, Yang, X, Bulkley, D, Chen, X.Z, Cao, E.
登録日2018-04-12
公開日2018-06-27
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.54 Å)
主引用文献Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.
Nat Commun, 9, 2018
4EWC
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BU of 4ewc by Molmil
Crystal Structure of the Infectious Salmon Anemia Virus Nucleoprotein
分子名称: Putative nucleoprotein
著者Zheng, W, Tao, Y.J.
登録日2012-04-26
公開日2013-05-08
最終更新日2015-02-25
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The crystal structure and RNA-binding of an orthomyxovirus nucleoprotein.
Plos Pathog., 9, 2013
6VEC
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BU of 6vec by Molmil
Cryo-EM structure of F-actin/Plastin2-ABD2 complex
分子名称: ADENOSINE-5'-DIPHOSPHATE, Actin, alpha skeletal muscle, ...
著者Zheng, W, Kudryashov, D.S, Egelman, E.H.
登録日2019-12-31
公開日2020-12-09
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Osteogenesis imperfecta mutations in plastin 3 lead to impaired calcium regulation of actin bundling.
Bone Res, 8, 2020
8YSA
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BU of 8ysa by Molmil
The co-crystal structure of SARS-CoV-2 Mpro in complex with compound H102
分子名称: 3C-like proteinase nsp5, BOC-TBG-PHE-ELL
著者Zheng, W.Y, Fu, L.F, Feng, Y, Han, P, Qi, J.X.
登録日2024-03-22
公開日2024-05-08
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Discovery, Biological Activity, and Structural Mechanism of a Potent Inhibitor of SARS-CoV-2 Main Protease
To Be Published
8EHX
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BU of 8ehx by Molmil
cryo-EM structure of TMEM63B in LMNG
分子名称: CSC1-like protein 2
著者Zheng, W, Fu, T.M, Holt, J.R.
登録日2022-09-14
公開日2023-08-23
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels.
Neuron, 111, 2023
8EHW
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BU of 8ehw by Molmil
cryo-EM structure of TMEM63A in nanodisc
分子名称: CSC1-like protein 1
著者Zheng, W, Fu, T.M, Holt, J.R.
登録日2022-09-14
公開日2023-08-23
最終更新日2023-11-01
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献TMEM63 proteins function as monomeric high-threshold mechanosensitive ion channels.
Neuron, 111, 2023
2ICK
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BU of 2ick by Molmil
Human isopentenyl diphophate isomerase complexed with substrate analog
分子名称: DIMETHYLALLYL DIPHOSPHATE, Isopentenyl-diphosphate delta isomerase, MANGANESE (II) ION
著者Zheng, W, Bartlam, M, Rao, Z.
登録日2006-09-12
公開日2007-03-20
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献The crystal structure of human isopentenyl diphosphate isomerase at 1.7 A resolution reveals its catalytic mechanism in isoprenoid biosynthesis
J.Mol.Biol., 366, 2007
2ICJ
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BU of 2icj by Molmil
The crystal structure of human isopentenyl diphophate isomerase
分子名称: Isopentenyl-diphosphate delta isomerase, MAGNESIUM ION, SULFATE ION
著者Zheng, W, Bartlam, M, Rao, Z.
登録日2006-09-12
公開日2007-03-20
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of human isopentenyl diphosphate isomerase at 1.7 A resolution reveals its catalytic mechanism in isoprenoid biosynthesis
J.Mol.Biol., 366, 2007
7K3R
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BU of 7k3r by Molmil
Cryo-EM structure of AIM2-PYD filament
分子名称: Interferon-inducible protein AIM2
著者Zheng, W, Matyszewski, M, Sohn, J, Egelman, E.H.
登録日2020-09-12
公開日2021-05-26
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Distinct axial and lateral interactions within homologous filaments dictate the signaling specificity and order of the AIM2-ASC inflammasome.
Nat Commun, 12, 2021
8UEU
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BU of 8ueu by Molmil
In-situ complex I, Deactive class03
分子名称: (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-10-02
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UEO
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BU of 8ueo by Molmil
In-situ complex I (Active-Apo)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-10-02
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UGL
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BU of 8ugl by Molmil
High resolution in-situ structure of complex IV in respiratory supercomplex
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-10-05
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UD1
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BU of 8ud1 by Molmil
High resolution in-situ structure of complex I in respiratory supercomplex (composite)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-09-27
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UGI
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BU of 8ugi by Molmil
High resolution in-situ structure of typeA supercomplex in respiratory chain (I1III2IV1,composite)
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
著者Zheng, W, Zhang, K, Zhu, J.
登録日2023-10-05
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024
8UEP
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BU of 8uep by Molmil
In-situ complex I, Active-Q10 (State-alpha)
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ...
著者Zheng, W, Zhu, J, Zhang, K.
登録日2023-10-02
公開日2024-06-19
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献High-resolution in situ structures of mammalian respiratory supercomplexes.
Nature, 631, 2024

 

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