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PDB: 676 件

4XWW
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BU of 4xww by Molmil
Crystal structure of RNase J complexed with RNA
分子名称: DR2417, GLYCEROL, MANGANESE (II) ION, ...
著者Lu, M, Zhang, H, Xu, Q, Hua, Y, Zhao, Y.
登録日2015-01-29
公開日2015-12-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J
Nucleic Acids Res., 43, 2015
4X2A
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BU of 4x2a by Molmil
Crystal structure of mouse glyoxalase I complexed with baicalein
分子名称: 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one, Lactoylglutathione lyase, ZINC ION
著者Zhang, H, Zhai, J, Zhang, L, Li, C, Zhao, Y, Hu, X.
登録日2014-11-26
公開日2015-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献In Vitro Inhibition of Glyoxalase І by Flavonoids: New Insights from Crystallographic Analysis.
Curr Top Med Chem, 16, 2016
1EEN
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BU of 1een by Molmil
CRYSTAL STRUCTURE OF PROTEIN TYROSINE PHOSPHATASE 1B COMPLEXED WITH ACETYL-D-A-D-BPA-PTYR-L-I-P-Q-Q-G
分子名称: ACETIC ACID, ALA-ASP-PBF-PTR-LEU-ILE-PRO, MAGNESIUM ION, ...
著者Puius, Y.A, Zhao, Y, Almo, S.C, Zhang, Z.Y.
登録日2000-02-01
公開日2001-02-01
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition.
Biochemistry, 39, 2000
8WFJ
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BU of 8wfj by Molmil
human glycine transporter 1 in complex with ALX-5407 in inward facing conformation
分子名称: ALX5407, Sodium- and chloride-dependent glycine transporter 1
著者Wei, Y, Zhao, Y.
登録日2023-09-19
公開日2024-04-03
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFK
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BU of 8wfk by Molmil
human glycine transporter 1 in complex with SSR504734 in outward facing conformation
分子名称: CHLORIDE ION, SODIUM ION, SSR504734, ...
著者Wei, Y, Zhao, Y.
登録日2023-09-19
公開日2024-04-03
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.22 Å)
主引用文献Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFL
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BU of 8wfl by Molmil
human glycine transporter 1 in complex with PF-03463275 in outward facing conformation
分子名称: PF-3463275, Sodium- and chloride-dependent glycine transporter 1
著者Wei, Y, Zhao, Y.
登録日2023-09-19
公開日2024-04-03
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
8WFI
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BU of 8wfi by Molmil
human glycine transporter 1 in complex with glycine in occluded conformation
分子名称: CHLORIDE ION, GLYCINE, Isoform GlyT-1B of Sodium- and chloride-dependent glycine transporter 1, ...
著者Wei, Y, Zhao, Y.
登録日2023-09-19
公開日2024-04-03
最終更新日2024-04-17
実験手法ELECTRON MICROSCOPY (2.58 Å)
主引用文献Transport mechanism and pharmacology of the human GlyT1.
Cell, 187, 2024
7BVC
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BU of 7bvc by Molmil
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol
分子名称: 4'-PHOSPHOPANTETHEINE, CALCIUM ION, CARDIOLIPIN, ...
著者Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
登録日2020-04-10
公開日2020-04-29
最終更新日2020-07-01
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
7BVF
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BU of 7bvf by Molmil
Cryo-EM structure of Mycobacterium tuberculosis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with ethambutol
分子名称: CALCIUM ION, CARDIOLIPIN, Ethambutol, ...
著者Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
登録日2020-04-10
公開日2020-04-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.97 Å)
主引用文献Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
7BVE
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BU of 7bve by Molmil
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbC2-AcpM2 in complex with ethambutol
分子名称: CALCIUM ION, Ethambutol, Integral membrane indolylacetylinositol arabinosyltransferase EmbC, ...
著者Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
登録日2020-04-10
公開日2020-04-29
最終更新日2020-07-01
実験手法ELECTRON MICROSCOPY (2.81 Å)
主引用文献Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
7BVG
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BU of 7bvg by Molmil
Cryo-EM structure of Mycobacterium smegmatis arabinosyltransferase EmbA-EmbB-AcpM2 in complex with di-arabinose.
分子名称: 4'-PHOSPHOPANTETHEINE, CALCIUM ION, CARDIOLIPIN, ...
著者Zhang, L, Zhao, Y, Gao, Y, Wang, Q, Li, J, Besra, G.S, Rao, Z.
登録日2020-04-10
公開日2020-04-29
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Structures of cell wall arabinosyltransferases with the anti-tuberculosis drug ethambutol.
Science, 368, 2020
7Y3E
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BU of 7y3e by Molmil
Cryo-EM structure of Arabidopsis thaliana SOS1 in an occluded state
分子名称: HEXADECANE, Sodium/hydrogen exchanger 7
著者Wang, Y, Zhao, Y, Gao, Y.
登録日2022-06-10
公開日2023-08-09
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Architecture and autoinhibitory mechanism of the plasma membrane Na + /H + antiporter SOS1 in Arabidopsis.
Nat Commun, 14, 2023
1EV7
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BU of 1ev7 by Molmil
CRYSTAL STRUCTURE OF DNA RESTRICTION ENDONUCLEASE NAEI
分子名称: TYPE IIE RESTRICTION ENDONUCLEASE NAEI
著者Huai, Q, Colandene, J.D, Chen, Y, Luo, F, Zhao, Y.
登録日2000-04-19
公開日2000-10-19
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.38 Å)
主引用文献Crystal structure of NaeI-an evolutionary bridge between DNA endonuclease and topoisomerase.
EMBO J., 19, 2000
4WJX
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BU of 4wjx by Molmil
Crystal structure of human chitotriosidase-1 catalytic domain at 1.0 A resolution
分子名称: Chitotriosidase-1, L(+)-TARTARIC ACID
著者Fadel, F, Zhao, Y, Cachau, R, Cousido-Siah, A, Ruiz, F.X, Harlos, K, Howard, E, Mitschler, A, Podjarny, A.
登録日2014-10-01
公開日2015-07-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1 Å)
主引用文献New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM
Acta Crystallogr.,Sect.D, 71, 2015
4WK9
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BU of 4wk9 by Molmil
Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (0.3mM) at 1.10 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitotriosidase-1
著者Fadel, F, Zhao, Y, Cachau, R, Cousido-Siah, A, Ruiz, F.X, Harlos, K, Howard, E, Mitschler, A, Podjarny, A.
登録日2014-10-02
公開日2015-07-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.102 Å)
主引用文献New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
4WKH
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BU of 4wkh by Molmil
Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (1mM) at 1.05 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitotriosidase-1
著者Fadel, F, Zhao, Y, Cachau, R, Cousido-Siah, A, Ruiz, F.X, Harlos, K, Howard, E, Mitschler, A, Podjarny, A.
登録日2014-10-02
公開日2015-07-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
4WKF
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BU of 4wkf by Molmil
Crystal structure of human chitotriosidase-1 catalytic domain in complex with chitobiose (2.5mM) at 1.10 A resolution
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chitotriosidase-1
著者Fadel, F, Zhao, Y, Cachau, R, Cousido-Siah, A, Ruiz, F.X, Harlos, K, Howard, E, Mitschler, A, Podjarny, A.
登録日2014-10-02
公開日2015-07-08
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.101 Å)
主引用文献New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
4WKA
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BU of 4wka by Molmil
Crystal structure of human chitotriosidase-1 catalytic domain at 0.95 A resolution
分子名称: Chitotriosidase-1, L(+)-TARTARIC ACID
著者Fadel, F, Zhao, Y, Cachau, R, Cousido-Siah, A, Ruiz, F.X, Harlos, K, Howard, E, Mitschler, A, Podjarny, A.
登録日2014-10-02
公開日2015-07-08
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (0.95 Å)
主引用文献New insights into the enzymatic mechanism of human chitotriosidase (CHIT1) catalytic domain by atomic resolution X-ray diffraction and hybrid QM/MM.
Acta Crystallogr.,Sect.D, 71, 2015
6OCR
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BU of 6ocr by Molmil
Crystal structure of human KCTD16 T1 domain
分子名称: BTB/POZ domain-containing protein KCTD16
著者Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R.
登録日2019-03-25
公開日2019-04-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.28 Å)
主引用文献Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
6OCT
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BU of 6oct by Molmil
Crystal structure of human KCTD16 T1 domain
分子名称: BTB/POZ domain-containing protein KCTD16
著者Zuo, H, Glaaser, I, Zhao, Y, Kurinov, I, Mosyak, L, Wang, H, Liu, J, Park, J, Frangaj, A, Sturchler, E, Zhou, M, McDonald, P, Geng, Y, Slesinger, P.A, Fan, Q.R.
登録日2019-03-25
公開日2019-04-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural basis for auxiliary subunit KCTD16 regulation of the GABABreceptor.
Proc.Natl.Acad.Sci.USA, 116, 2019
7YG5
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BU of 7yg5 by Molmil
Structure of human R-type voltage-gated CaV2.3-alpha2/delta1-beta1 channel complex in the topiramate-bound state
分子名称: 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
著者Gao, Y, Zhao, Y.
登録日2022-07-11
公開日2023-11-29
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into allosteric effects of antiepileptic drug topiramate on CaV2.3 channel.
To Be Published
1M63
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BU of 1m63 by Molmil
Crystal structure of calcineurin-cyclophilin-cyclosporin shows common but distinct recognition of immunophilin-drug complexes
分子名称: CALCINEURIN B SUBUNIT ISOFORM 1, CALCIUM ION, CYCLOSPORIN A, ...
著者Huai, Q, Kim, H.-Y, Liu, Y, Zhao, Y, Mondragon, A, Liu, J.O, Ke, H.
登録日2002-07-12
公開日2002-09-25
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Calcineurin-Cyclophilin-Cyclosporin Shows Common But Distinct Recognition of Immunophilin-Drug Complexes
Proc.Natl.Acad.Sci.USA, 99, 2002
4AGH
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BU of 4agh by Molmil
Structural features of ssDNA binding protein MoSub1 from Magnaporthe oryzae
分子名称: MOSUB1, TRANSCRIPTION COFACTOR
著者Huang, J, Zhao, Y, Huang, D, liu, J, Peng, Y.
登録日2012-01-27
公開日2012-08-29
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.787 Å)
主引用文献Structural Features of the Single-Stranded DNA-Binding Protein Mosub1 from Magnaporthe Oryzae.
Acta Crystallogr.,Sect.D, 68, 2012
1F0J
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BU of 1f0j by Molmil
CATALYTIC DOMAIN OF HUMAN PHOSPHODIESTERASE 4B2B
分子名称: ARSENIC, MAGNESIUM ION, PHOSPHODIESTERASE 4B, ...
著者Xu, R.X, Hassell, A.M, Vanderwall, D, Lambert, M.H, Holmes, W.D, Luther, M.A, Rocque, W.J, Milburn, M.V, Zhao, Y, Ke, H, Nolte, R.T.
登録日2000-05-16
公開日2000-07-26
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity.
Science, 288, 2000
4BHM
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BU of 4bhm by Molmil
The crystal structure of MoSub1-DNA complex reveals a novel DNA binding mode
分子名称: 5'-D(*TP*TP*TP*TP*TP*TP*TP*TP)-3', MOSUB1 TRANSCRIPTION COFACTOR, SULFATE ION
著者Huang, J, Liu, H, Zhao, Y, Huang, D, liu, J, Peng, Y.
登録日2013-04-04
公開日2014-04-23
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Substitution of Tryptophan 89 with Tyrosine Switches the DNA Binding Mode of Pc4.
Sci.Rep., 5, 2015

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