8WFK

human glycine transporter 1 in complex with SSR504734 in outward facing conformation

Summary for 8WFK

Entry DOI	10.2210/pdb8wfk/pdb
EMDB information	37494
Descriptor	Sodium- and chloride-dependent glycine transporter 1, SSR504734, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	glyt1, ssr504734, membrane protein
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	73011.41
Authors	Wei, Y.,Zhao, Y. (deposition date: 2023-09-19, release date: 2024-04-03, Last modification date: 2024-04-17)
Primary citation	Wei, Y.,Li, R.,Meng, Y.,Hu, T.,Zhao, J.,Gao, Y.,Bai, Q.,Li, N.,Zhao, Y. Transport mechanism and pharmacology of the human GlyT1. Cell, 187:1719-, 2024 Cited by PubMed: 38513663 DOI: 10.1016/j.cell.2024.02.026 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.22 Å)

Structure validation