1EXZ
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![BU of 1exz by Molmil](/molmil-images/mine/1exz) | STRUCTURE OF STEM CELL FACTOR | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, SAMARIUM (III) ION, ... | Authors: | Zhang, Z, Zhang, R, Joachimiak, A, Schlessinger, J, Kong, X. | Deposit date: | 2000-05-05 | Release date: | 2000-07-06 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of human stem cell factor: implication for stem cell factor receptor dimerization and activation. Proc.Natl.Acad.Sci.USA, 97, 2000
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7CM7
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![BU of 7cm7 by Molmil](/molmil-images/mine/7cm7) | NAD+-bound Sarm1 E642A in the self-inhibited state | Descriptor: | NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Zhang, Z, Jiang, Y. | Deposit date: | 2020-07-25 | Release date: | 2020-10-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1. Nature, 588, 2020
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7CM6
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![BU of 7cm6 by Molmil](/molmil-images/mine/7cm6) | NAD+-bound Sarm1 in the self-inhibited state | Descriptor: | NAD(+) hydrolase SARM1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | Authors: | Zhang, Z, Jiang, Y. | Deposit date: | 2020-07-25 | Release date: | 2020-10-21 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | The NAD + -mediated self-inhibition mechanism of pro-neurodegenerative SARM1. Nature, 588, 2020
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6Y53
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![BU of 6y53 by Molmil](/molmil-images/mine/6y53) | human 17S U2 snRNP low resolution part | Descriptor: | HIV Tat-specific factor 1, Probable ATP-dependent RNA helicase DDX46, Small nuclear ribonucleoprotein E, ... | Authors: | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | Deposit date: | 2020-02-24 | Release date: | 2020-06-17 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
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6Y5Q
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![BU of 6y5q by Molmil](/molmil-images/mine/6y5q) | human 17S U2 snRNP | Descriptor: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | Authors: | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | Deposit date: | 2020-02-25 | Release date: | 2020-06-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (7.1 Å) | Cite: | Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
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3O5X
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![BU of 3o5x by Molmil](/molmil-images/mine/3o5x) | Crystal structure of the oncogenic tyrosine phosphatase SHP2 complexed with a salicylic acid-based small molecule inhibitor | Descriptor: | 3-{1-[3-(biphenyl-4-ylamino)-3-oxopropyl]-1H-1,2,3-triazol-4-yl}-6-hydroxy-1-methyl-2-phenyl-1H-indole-5-carboxylic acid, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Zhang, Z.-Y, Zhang, X, He, Y, Liu, S, Yu, Z, Jiang, Z, Yang, Z, Dong, Y, Nabinger, S.C, Wu, L, Gunawan, A.M, Wang, L, Chan, R.J. | Deposit date: | 2010-07-28 | Release date: | 2010-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Salicylic acid based small molecule inhibitor for the oncogenic Src homology-2 domain containing protein tyrosine phosphatase-2 (SHP2). J.Med.Chem., 53, 2010
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6Y50
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![BU of 6y50 by Molmil](/molmil-images/mine/6y50) | 5'domain of human 17S U2 snRNP | Descriptor: | HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, Probable ATP-dependent RNA helicase DDX46, ... | Authors: | Zhang, Z, Will, C.L, Bertram, K, Luehrmann, R, Stark, H. | Deposit date: | 2020-02-24 | Release date: | 2020-07-01 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Molecular architecture of the human 17S U2 snRNP. Nature, 583, 2020
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1TPB
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![BU of 1tpb by Molmil](/molmil-images/mine/1tpb) | OFFSET OF A CATALYTIC LESION BY A BOUND WATER SOLUBLE | Descriptor: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Knowles, J.R, Petsko, G.A, Ringe, D. | Deposit date: | 1994-02-03 | Release date: | 1995-02-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules. Biochemistry, 34, 1995
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1TPC
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![BU of 1tpc by Molmil](/molmil-images/mine/1tpc) | OFFSET OF A CATALYTIC LESION BY A BOUND WATER SOLUBLE | Descriptor: | PHOSPHOGLYCOLOHYDROXAMIC ACID, TRIOSEPHOSPHATE ISOMERASE | Authors: | Zhang, Z, Sugio, S, Komives, E.A, Liu, K.D, Knowles, J.R, Petsko, G.A, Ringe, D. | Deposit date: | 1994-02-03 | Release date: | 1995-02-14 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules. Biochemistry, 34, 1995
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8ZMR
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![BU of 8zmr by Molmil](/molmil-images/mine/8zmr) | Vesamicol-bound VAChT | Descriptor: | Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7, vesamicol | Authors: | Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. | Deposit date: | 2024-05-23 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res., 2024
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8ZMS
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![BU of 8zms by Molmil](/molmil-images/mine/8zms) | Acetylcholine-bound VAChT | Descriptor: | ACETYLCHOLINE, Maltose/maltodextrin-binding periplasmic protein,Vesicular acetylcholine transporter,DARPinoff7 | Authors: | Zhang, Z, Zhang, Y, Dai, F, Zhang, Y.X, Lee, C.-H. | Deposit date: | 2024-05-23 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Structural insights into VAChT neurotransmitter recognition and inhibition. Cell Res., 2024
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4YJL
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![BU of 4yjl by Molmil](/molmil-images/mine/4yjl) | Crystal structure of APC-ARM in complexed with Amer1-A2 | Descriptor: | 1,2-ETHANEDIOL, APC membrane recruitment protein 1, Adenomatous polyposis coli protein | Authors: | Zhang, Z, Xiao, Y, Wu, G. | Deposit date: | 2015-03-03 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners Cell Discov, 1, 2015
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6F57
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![BU of 6f57 by Molmil](/molmil-images/mine/6f57) | |
3H1J
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![BU of 3h1j by Molmil](/molmil-images/mine/3h1j) | Stigmatellin-bound cytochrome bc1 complex from chicken | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, CARDIOLIPIN, Coenzyme Q10, ... | Authors: | Zhang, Z, Huang, L, Shulmeister, V.M, Chi, Y.-I, Kim, K.K, Hung, L.-W, Crofts, A.R, Berry, E.A, Kim, S.-H. | Deposit date: | 2009-04-12 | Release date: | 2009-04-28 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Electron Transfer by Domain Movement in Cytochrome Bc1 Nature, 392, 1998
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4YJE
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![BU of 4yje by Molmil](/molmil-images/mine/4yje) | Crystal structure of APC-ARM in complexed with Amer1-A1 | Descriptor: | APC membrane recruitment protein 1, Adenomatous polyposis coli protein | Authors: | Zhang, Z, Xiao, Y, Wu, G. | Deposit date: | 2015-03-03 | Release date: | 2016-03-09 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structures of the APC-ARM domain in complexes with discrete Amer1/WTX fragments reveal that it uses a consensus mode to recognize its binding partners Cell Discov, 1, 2015
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1ZUC
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![BU of 1zuc by Molmil](/molmil-images/mine/1zuc) | Progesterone receptor ligand binding domain in complex with the nonsteroidal agonist tanaproget | Descriptor: | 5-(4,4-DIMETHYL-2-THIOXO-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-6-YL)-1-METHYL-1H-PYRROLE-2-CARBONITRILE, Progesterone receptor, SULFATE ION | Authors: | Zhang, Z, Olland, A.M, Zhu, Y, Cohen, J, Berrodin, T, Chippari, S, Appavu, C, Li, S, Wilhem, J, Chopra, R, Fensome, A, Zhang, P, Wrobel, J, Unwalla, R.J, Lyttle, C.R, Winneker, R.C. | Deposit date: | 2005-05-30 | Release date: | 2005-07-05 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget J.Biol.Chem., 280, 2005
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4GE2
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![BU of 4ge2 by Molmil](/molmil-images/mine/4ge2) | |
8K7T
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![BU of 8k7t by Molmil](/molmil-images/mine/8k7t) | Mouse Fc epsilon RI in complex with mIgE Fc | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, High affinity immunoglobulin epsilon receptor subunit alpha, High affinity immunoglobulin epsilon receptor subunit beta, ... | Authors: | Zhang, Z, Yui, M, Ohto, U, Shimizu, T. | Deposit date: | 2023-07-27 | Release date: | 2024-07-17 | Method: | ELECTRON MICROSCOPY (3.71 Å) | Cite: | Mouse Fc epsilon RI in complex withMouse Fc epsilon RI in complex with mIgE Fc mIgE Fc To Be Published
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1JW6
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![BU of 1jw6 by Molmil](/molmil-images/mine/1jw6) | Crystal Structure of the Complex of Concanavalin A and Hexapeptide | Descriptor: | CALCIUM ION, Concanavalin A, ISOPROPYL ALCOHOL, ... | Authors: | Zhang, Z, Qian, M, Huang, Q, Jia, Y, Tang, Y. | Deposit date: | 2001-09-02 | Release date: | 2001-09-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Crystal structure of the complex of concanavalin A and hexapeptide. J.Protein Chem., 20, 2001
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4GE5
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![BU of 4ge5 by Molmil](/molmil-images/mine/4ge5) | |
4RL5
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![BU of 4rl5 by Molmil](/molmil-images/mine/4rl5) | |
2QMY
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![BU of 2qmy by Molmil](/molmil-images/mine/2qmy) | Quinone Reductase 2 in complex with adrenochrome | Descriptor: | (3S)-3-hydroxy-1-methyl-2,3-dihydro-1H-indole-5,6-dione, FLAVIN-ADENINE DINUCLEOTIDE, Ribosyldihydronicotinamide dehydrogenase, ... | Authors: | Zhang, Z, Fu, Y, Buryanovskky, L. | Deposit date: | 2007-07-17 | Release date: | 2008-06-24 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Quinone Reductase 2 regulates Catecholamine oxidation To be Published
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1DS0
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![BU of 1ds0 by Molmil](/molmil-images/mine/1ds0) | CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE | Descriptor: | ACETATE ION, CLAVAMINATE SYNTHASE 1, SULFATE ION | Authors: | Zhang, Z.H, Ren, J, Stammers, D.K, Baldwin, J.E, Harlos, K, Schofield, C.J. | Deposit date: | 2000-01-06 | Release date: | 2000-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase. Nat.Struct.Biol., 7, 2000
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4RDD
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![BU of 4rdd by Molmil](/molmil-images/mine/4rdd) | Co-crystal structure of SHP2 in complex with a Cefsulodin derivative | Descriptor: | 1-({(2R)-4-carboxy-2-[(R)-carboxy{[(2R)-2-phenyl-2-sulfoacetyl]amino}methyl]-3,6-dihydro-2H-1,3-thiazin-5-yl}methyl)pyridinium, Tyrosine-protein phosphatase non-receptor type 11 | Authors: | Zhang, Z.Y, Yu, Z.H, He, R, Zhang, R.Y. | Deposit date: | 2014-09-18 | Release date: | 2015-07-01 | Last modified: | 2015-12-16 | Method: | X-RAY DIFFRACTION (1.601 Å) | Cite: | Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors. ACS Med Chem Lett, 6, 2015
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1MD2
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![BU of 1md2 by Molmil](/molmil-images/mine/1md2) | CHOLERA TOXIN B-PENTAMER WITH DECAVALENT LIGAND BMSC-0013 | Descriptor: | 3-ETHYLAMINO-4-METHYLAMINO-CYCLOBUTANE-1,2-DIONE, CHOLERA TOXIN B SUBUNIT, CYANIDE ION, ... | Authors: | Zhang, Z, Merritt, E.A, Ahn, M, Roach, C, Hol, W.G.J, Fan, E. | Deposit date: | 2002-08-06 | Release date: | 2002-12-11 | Last modified: | 2017-10-11 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Solution and crystallographic studies of branched multivalent ligands that inhibit the receptor-binding of cholera toxin. J.Am.Chem.Soc., 124, 2002
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