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PDB: 723 件

6CEB
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Insulin Receptor ectodomain in complex with two insulin molecules - C1 symmetry
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Scapin, G, Dandey, V.P, Zhang, Z, Strickland, C, Potter, C.S, Carragher, B.
登録日2018-02-11
公開日2018-03-14
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Structure of the insulin receptor-insulin complex by single-particle cryo-EM analysis.
Nature, 556, 2018
5ZB9
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Crystal structure of Rtt109 from Aspergillus fumigatus
分子名称: DNA damage response protein Rtt109, putative, GLYCEROL
著者Zhang, L, Serra-Cardona, A, Zhou, H, Wang, M, Yang, N, Zhang, Z, Xu, R.M.
登録日2018-02-10
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.502 Å)
主引用文献Multisite Substrate Recognition in Asf1-Dependent Acetylation of Histone H3 K56 by Rtt109.
Cell, 174, 2018
4HUH
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Structure of the bacteriophage T4 tail terminator protein, gp15 (C-terminal truncation mutant 1-261).
分子名称: Tail connector protein Gp15
著者Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G.
登録日2012-11-02
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
7QE7
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BU of 7qe7 by Molmil
High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1
分子名称: Anaphase-promoting complex subunit 1, Anaphase-promoting complex subunit 10, Anaphase-promoting complex subunit 11, ...
著者Hoefler, A, Yu, J, Chang, L, Zhang, Z, Yang, J, Boland, A, Barford, D.
登録日2021-12-01
公開日2022-01-26
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献High-resolution structure of the Anaphase-promoting complex (APC/C) bound to co-activator Cdh1
To Be Published
4JN9
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BU of 4jn9 by Molmil
Crystal structure of the DepH
分子名称: 1,2-ETHANEDIOL, CHLORIDE ION, DepH, ...
著者Li, J, Wang, C, Zhang, Z.M, Zhou, J.H, Cheng, E.
登録日2013-03-14
公開日2014-04-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis of an NADP+-independent dithiol oxidase in FK228 biosynthesis.
Sci Rep, 4, 2014
7ARM
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BU of 7arm by Molmil
LolCDE in complex with lipoprotein and LolA
分子名称: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARL
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BU of 7arl by Molmil
LolCDE in complex with lipoprotein and ADP
分子名称: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, ADENOSINE-5'-DIPHOSPHATE, LPP, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Shen, C.R, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Wei, X.W, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARK
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BU of 7ark by Molmil
LolCDE in complex with AMP-PNP in the closed NBD state
分子名称: Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARJ
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BU of 7arj by Molmil
LolCDE in complex with lipoprotein and AMPPNP complex undimerized form
分子名称: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARI
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BU of 7ari by Molmil
LolCDE apo structure
分子名称: Lipoprotein-releasing ABC transporter permease subunit LolC, Lipoprotein-releasing system ATP-binding protein LolD, Lipoprotein-releasing system transmembrane protein LolE
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
7ARH
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BU of 7arh by Molmil
LolCDE in complex with lipoprotein
分子名称: (2S)-3-hydroxypropane-1,2-diyl dihexadecanoate, LPP, Lipoprotein-releasing ABC transporter permease subunit LolC, ...
著者Tang, X.D, Chang, S.H, Zhang, K, Wang, T, Luo, Q.H, Qiao, W, Wang, C, Zhang, Z.B, Zhang, Z.Y, Zhu, X.F, Dong, C.J, Zhang, X, Dong, H.H.
登録日2020-10-25
公開日2021-04-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis for bacterial lipoprotein relocation by the transporter LolCDE.
Nat.Struct.Mol.Biol., 28, 2021
4HUD
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BU of 4hud by Molmil
Structure of the bacteriophage T4 tail terminator protein, gp15.
分子名称: Tail connector protein Gp15
著者Fokine, A, Zhang, Z, Kanamaru, S, Bowman, V.D, Aksyuk, A, Arisaka, F, Rao, V.B, Rossmann, M.G.
登録日2012-11-02
公開日2013-02-27
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7001 Å)
主引用文献The molecular architecture of the bacteriophage t4 neck.
J.Mol.Biol., 425, 2013
2FF0
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BU of 2ff0 by Molmil
Solution Structure of Steroidogenic Factor 1 DNA Binding Domain Bound to its Target Sequence in the Inhibin alpha-subunit Promoter
分子名称: CTGTGGCCCTGAGCC, GGCTCAGGGCCACAG, Steroidogenic factor 1, ...
著者Little, T.H, Zhang, Y, Matulis, C.K, Weck, J, Zhang, Z, Ramachandran, A, Mayo, K.E, Radhakrishnan, I.
登録日2005-12-17
公開日2006-04-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Sequence-specific deoxyribonucleic Acid (DNA) recognition by steroidogenic factor 1: a helix at the carboxy terminus of the DNA binding domain is necessary for complex stability.
Mol.Endocrinol., 20, 2006
4L08
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BU of 4l08 by Molmil
Crystal structure of the maleamate amidase Ami(C149A) in complex with maleate from Pseudomonas putida S16
分子名称: Hydrolase, isochorismatase family, MALEIC ACID
著者Chen, D.D, Lu, Y, Zhang, Z, Wu, G, Xu, P.
登録日2013-05-31
公開日2014-07-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.66 Å)
主引用文献Structural insights into the specific recognition of N-heterocycle biodenitrogenation-derived substrates by microbial amide hydrolases.
Mol.Microbiol., 91, 2014
5XEY
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BU of 5xey by Molmil
Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus
分子名称: 1-[2,4,6-tris(oxidanyl)phenyl]ethanone, phloretin hydrolase
著者He, Y.X, Han, J.T, Jia, W.J, Zhang, Z.
登録日2017-04-06
公開日2018-05-02
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Discovery and structural analysis of a phloretin hydrolase from the opportunistic human pathogen Mycobacterium abscessus.
FEBS J., 2019
4MW2
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BU of 4mw2 by Molmil
Trypanosoma brucei methionyl-tRNA synthetase in complex with inhibitor 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea (Chem 1472)
分子名称: 1-(3-{[5-chloro-2-hydroxy-3-(prop-2-en-1-yl)benzyl]amino}propyl)-3-thiophen-3-ylurea, DIMETHYL SULFOXIDE, GLYCEROL, ...
著者Koh, C.Y, Kim, J.E, Wetzel, A.B, de van der Schueren, W.J, Shibata, S, Liu, J, Zhang, Z, Fan, E, Verlinde, C.L.M.J, Hol, W.G.J.
登録日2013-09-24
公開日2014-04-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of Trypanosoma brucei Methionyl-tRNA Synthetase with Urea-Based Inhibitors Provide Guidance for Drug Design against Sleeping Sickness.
Plos Negl Trop Dis, 8, 2014
5XE5
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BU of 5xe5 by Molmil
Discovery and structural analysis of a phloretin hydrolase from the opportunistic pathogen Mycobacterium abscessus
分子名称: 1,2-ETHANEDIOL, MAGNESIUM ION, phloretin hydrolase
著者He, Y.X, Han, J.T, Jia, W.J, Zhang, Z.
登録日2017-04-01
公開日2018-05-02
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Discovery and structural analysis of a phloretin hydrolase from the opportunistic human pathogen Mycobacterium abscessus.
FEBS J., 2019
4L07
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BU of 4l07 by Molmil
Crystal structure of the maleamate amidase Ami from Pseudomonas putida S16
分子名称: GLYCEROL, Hydrolase, isochorismatase family, ...
著者Chen, D.D, Lu, Y, Zhang, Z, Wu, G, Xu, P.
登録日2013-05-30
公開日2014-07-16
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural insights into the specific recognition of N-heterocycle biodenitrogenation-derived substrates by microbial amide hydrolases.
Mol.Microbiol., 91, 2014
7ON1
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BU of 7on1 by Molmil
Cenp-A nucleosome in complex with Cenp-C
分子名称: BJ4_G0006610.mRNA.1.CDS.1, BJ4_G0007000.mRNA.1.CDS.1, DNA (123-MER), ...
著者Yan, K, Yang, J, Zhang, Z, Barford, D.
登録日2021-05-25
公開日2021-07-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.35 Å)
主引用文献Cenp-A nucleosome in complex with Cenp-C
To Be Published
6U8V
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BU of 6u8v by Molmil
Crystal structure of DNMT3B-DNMT3L in complex with CpGpT DNA
分子名称: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
著者Gao, L, Zhang, Z.M, Song, J.
登録日2019-09-06
公開日2020-06-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
6U8W
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BU of 6u8w by Molmil
Crystal structure of DNMT3B(K777A)-DNMT3L in complex with CpGpT DNA
分子名称: CpGpT DNA (25-MER), DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3B, ...
著者Gao, L, Zhang, Z.M, Song, J.
登録日2019-09-06
公開日2020-06-10
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.94891548 Å)
主引用文献Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms.
Nat Commun, 11, 2020
8WX3
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BU of 8wx3 by Molmil
Cryo-EM structure of human SLC15A4 (outward-facing open)
分子名称: Solute carrier family 15 member 4
著者Sakaniwa, K, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-06
実験手法ELECTRON MICROSCOPY (2.83 Å)
主引用文献Cryo-EM structure of human SLC15A4 (outward-facing open)
To Be Published
8WX2
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BU of 8wx2 by Molmil
Cryo-EM structure of human SLC15A3 (dimer)
分子名称: Solute carrier family 15 member 3
著者Kasai, S, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-06
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.44 Å)
主引用文献Cryo-EM structure of human SLC15A3 (outward-facing partially occluded)
To Be Published
8WX4
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Cryo-EM structure of human SLC15A4 in complex with Lys-Leu (outward-facing open)
分子名称: LEUCINE, LYSINE, Solute carrier family 15 member 4
著者Sakaniwa, K, Zhang, Z, Ohto, U, Shimizu, T.
登録日2023-10-27
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.12 Å)
主引用文献Cryo-EM structure of human SLC15A4 in complex with Lys-Leu (outward-facing open)
To Be Published
5YOF
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BU of 5yof by Molmil
Crystal structure of zika virus NS3 protease in complex with a dipeptide inhibitor
分子名称: (S)-2-acetamido-6-amino-N-((S)-5-guanidino-1-oxopentan-2-yl)hexanamide, NS2B cofactor, NS3 Protease
著者Phoo, W.W, Zhang, Z.Z.
登録日2017-10-27
公開日2018-03-21
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Structural Insights into the Inhibition of Zika Virus NS2B-NS3 Protease by a Small-Molecule Inhibitor
Structure, 26, 2018

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