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PDB: 118 件

5V43
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Engineered human IgG Fc domain aglyco801
分子名称: Ig gamma-1 chain C region
著者Yan, W, Marshall, N, Zhang, Y.J.
登録日2017-03-08
公開日2017-06-21
最終更新日2017-09-27
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
5C2Y
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Crystal structure of the Saccharomyces cerevisiae Rtr1 (regulator of transcription)
分子名称: GLYCEROL, RNA polymerase II subunit B1 CTD phosphatase RTR1, SULFATE ION, ...
著者Yogesha, S.D, Irani, S, Zhang, Y.J.
登録日2015-06-16
公開日2016-05-04
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure of Saccharomyces cerevisiae Rtr1 reveals an active site for an atypical phosphatase.
Sci.Signal., 9, 2016
6DAQ
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PhdJ bound to substrate intermediate
分子名称: PhdJ
著者Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P.
登録日2018-05-01
公開日2019-04-10
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily.
Biochemistry, 57, 2018
6DAO
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NahE WT selenomethionine
分子名称: Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase
著者Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P.
登録日2018-05-01
公開日2019-05-08
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (1.939 Å)
主引用文献Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily.
Biochemistry, 57, 2018
6DU3
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Structure of Scp1 D96N bound to REST-pS861/4 peptide
分子名称: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861
著者Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
登録日2018-06-19
公開日2018-09-26
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.58 Å)
主引用文献Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
6DU2
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Structure of Scp1 D96N bound to REST-pS861/4 peptide
分子名称: MAGNESIUM ION, REST-pS861/4, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2
著者Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
登録日2018-06-19
公開日2018-09-26
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
6DAN
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BU of 6dan by Molmil
PhdJ WT 2 Angstroms resolution
分子名称: CHLORIDE ION, PhdJ
著者Medellin, B.P, LeVieux, J.A, Zhang, Y.J, Whitman, C.P.
登録日2018-05-01
公開日2019-04-10
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Structural Characterization of the Hydratase-Aldolases, NahE and PhdJ: Implications for the Specificity, Catalysis, and N-Acetylneuraminate Lyase Subgroup of the Aldolase Superfamily.
Biochemistry, 57, 2018
5V4E
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Engineered human IgG Fc domain glyco801 (Fc801)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Yan, W, Marshall, N, Zhang, Y.J.
登録日2017-03-09
公開日2017-06-21
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.216 Å)
主引用文献IgG Fc domains that bind C1q but not effector Fc gamma receptors delineate the importance of complement-mediated effector functions.
Nat. Immunol., 18, 2017
6VVR
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Q0 fused 4-OT wild type symmetric trimer
分子名称: Tautomerase
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2020-02-18
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 59, 2020
6VVM
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R7 fused 4-OT wild type asymmetric trimer
分子名称: 4-oxalocrotonate tautomerase family enzyme
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2020-02-18
公開日2020-04-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Structural Basis for the Asymmetry of a 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 59, 2020
8DO5
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BU of 8do5 by Molmil
Crystal structure of NahE in complex with intermediate (R)-4-hydroxy-4-(2-hydroxyphenyl)-2-iminobutanoate
分子名称: (4R)-4-hydroxy-4-(2-hydroxyphenyl)butanoic acid, DIMETHYL SULFOXIDE, Trans-ohydrobenzylidenepyruvate hydratase aldolase
著者LeVieux, J.A, Hardtke, H.A, Zhang, Y.J.
登録日2022-07-12
公開日2022-12-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献A mutagenic analysis of NahE, a hydratase-aldolase in the naphthalene degradative pathway.
Arch.Biochem.Biophys., 733, 2023
5UIF
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BU of 5uif by Molmil
Crystal Structure of Native Ps01740
分子名称: Ps01740
著者LeVieux, J, Baas, B.J, Zhang, Y.J, Whitman, C.P.
登録日2017-01-13
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.57 Å)
主引用文献Kinetic and structural characterization of a cis-3-Chloroacrylic acid dehalogenase homologue in Pseudomonas sp. UW4: A potential step between subgroups in the tautomerase superfamily.
Arch. Biochem. Biophys., 636, 2017
6BLM
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BU of 6blm by Molmil
Crystal Structure of Native Fused 4-OT
分子名称: 4-oxalocrotonate tautomerase
著者LeVieux, J, Baas, B.J, Zhang, Y.J, Whitman, C.P.
登録日2017-11-10
公開日2017-12-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.488 Å)
主引用文献A global view of structure-function relationships in the tautomerase superfamily.
J. Biol. Chem., 293, 2018
8T9O
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Crystal structure of CF, a heterohexamer of the 4-oxalocrotonate tautomerase (4-OT) family
分子名称: Tautomerase alpha subunit, Tautomerase beta subunit
著者Moreno, R.Y, Zhang, Y.J.
登録日2023-06-24
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases.
Biochemistry, 62, 2023
8T9P
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Crystal Structure of YR, a heterohexamer of the 4-oxalocrotonate tautomerase (4-OT) family
分子名称: Tautomerase alpha subunit, Tautomerase beta subunit
著者Moreno, R.Y, Zhang, Y.J.
登録日2023-06-24
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases.
Biochemistry, 62, 2023
8T9Q
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BU of 8t9q by Molmil
Crystal structure of fused YR, an asymmetric 4-OT trimer
分子名称: Tautomerase
著者Moreno, R.Y, Zhang, Y.J.
登録日2023-06-24
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Introduction of Asymmetry in the Fused 4-Oxalocrotonate Tautomerases.
Biochemistry, 62, 2023
8UKE
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BU of 8uke by Molmil
Crystal Structure of Norbelladine O-methyltransferase variant in complex with SAH
分子名称: CALCIUM ION, Norbelladine 4'-O-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE
著者Kim, W, Zhang, Y.J.
登録日2023-10-12
公開日2024-03-20
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Biosensor and machine learning-aided engineering of an amaryllidaceae enzyme.
Nat Commun, 15, 2024
6OGM
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Crystal structure of apo unFused 4-OT
分子名称: 4-oxalocrotonate tautomerase, GLYCEROL
著者Medellin, B.P, Whitman, C.P, Zhang, Y.J.
登録日2019-04-03
公開日2020-02-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.865 Å)
主引用文献Structural, Kinetic, and Mechanistic Analysis of an Asymmetric 4-Oxalocrotonate Tautomerase Trimer.
Biochemistry, 58, 2019
7M59
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BU of 7m59 by Molmil
Crystal structure of N2, a member of 4-oxalocrotonate tautomerase (4-OT) family
分子名称: Tautomerase domain-containing protein
著者Medellin, B.P, Moreno, R.Y, Zhang, Y.J.
登録日2021-03-23
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications.
Biochemistry, 60, 2021
7M58
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BU of 7m58 by Molmil
Crystal structure of N1, a member of cis-3-chloroacrylic acid dehalogenase (cis-CaaD) family
分子名称: SULFATE ION, Tautomerase_3 domain-containing protein
著者Medellin, B.P, Moreno, R.Y, Zhang, Y.J.
登録日2021-03-22
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Kinetic and Structural Analysis of Two Linkers in the Tautomerase Superfamily: Analysis and Implications.
Biochemistry, 60, 2021
6AKS
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BU of 6aks by Molmil
Cryo-EM structure of CVA10 mature virus
分子名称: SPHINGOSINE, VP1, VP2, ...
著者Zhu, L, Sun, Y, Fan, J.Y, Zhu, B, Cao, L, Gao, Q, Zhang, Y.J, Liu, H.R, Rao, Z.H, Wang, X.X.
登録日2018-09-03
公開日2019-01-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating.
Nat Commun, 9, 2018
6AKT
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BU of 6akt by Molmil
Cryo-EM structure of CVA10 A-particle
分子名称: VP1, VP2, VP3
著者Zhu, L, Sun, Y, Fan, J.Y, Zhu, B, Cao, L, Gao, Q, Zhang, Y.J, Liu, H.R, Rao, Z.H, Wang, X.X.
登録日2018-09-03
公開日2019-01-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating.
Nat Commun, 9, 2018
6AKU
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BU of 6aku by Molmil
Cryo-EM structure of CVA10 empty particle
分子名称: VP1, VP2, VP3
著者Zhu, L, Sun, Y, Fan, J.Y, Zhu, B, Cao, L, Gao, Q, Zhang, Y.J, Liu, H.R, Rao, Z.H, Wang, X.X.
登録日2018-09-03
公開日2019-01-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating.
Nat Commun, 9, 2018
7TVK
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BU of 7tvk by Molmil
Structural, Kinetic, and Mechanistic Analysis of the Wild-Type and Inactivated Malonate Semialdehyde Decarboxylase: A Structural Basis for the Decarboxylase and Hydratase Activities
分子名称: Malonate Semialdehyde Decarboxylase
著者Yang, W.J, Zhang, Y.J.
登録日2022-02-05
公開日2022-12-21
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Kinetic, Inhibition, and Structural Characterization of a Malonate Semialdehyde Decarboxylase-like Protein from Calothrix sp. PCC 6303: A Gateway to the non-Pro1 Tautomerase Superfamily Members.
Biochemistry, 2022
7Y3Z
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BU of 7y3z by Molmil
Structure of a novel carboxylesterase FEH from Acinetobacter sp. DL-2
分子名称: Fenoxaprop-p-ethyl hydrolase
著者Huang, Y, Liu, W.D, Zhang, Y.J, Duan, Y.J, Lu, M.L.
登録日2022-06-13
公開日2023-07-19
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structure of a novel carboxylesterase FEH from Acinetobacter sp. DL-2
To Be Published

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件を2024-07-24に公開中

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