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PDB: 422 件

3CYY
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The crystal structure of ZO-1 PDZ2 in complex with the Cx43 peptide
分子名称: Tight junction protein ZO-1, peptide from Gap junction alpha-1 protein
著者Pan, L, Zhang, M.
登録日2008-04-27
公開日2008-09-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sites
Embo J., 27, 2008
5IH4
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Human Casein Kinase 1 isoform delta apo (kinase domain)
分子名称: Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, SULFATE ION, ...
著者Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H.
登録日2016-02-29
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1.
Cell Chem Biol, 23, 2016
6ALE
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A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
分子名称: (3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin-2, ...
著者Nam, Y.W, Zhang, M.
登録日2017-08-07
公開日2018-08-08
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model.
Sci Rep, 8, 2018
5IH6
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Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A derivative
分子名称: 6-(3-bromophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ...
著者Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H.
登録日2016-02-29
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1.
Cell Chem Biol, 23, 2016
6CU7
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Alpha Synuclein fibril formed by full length protein - Rod Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
5IH5
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Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A
分子名称: 6-(3-chlorophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ...
著者Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H.
登録日2016-02-29
公開日2016-04-13
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1.
Cell Chem Biol, 23, 2016
6CU8
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Alpha Synuclein fibril formed by full length protein - Twister Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
6CZQ
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A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
分子名称: CALCIUM ION, Calmodulin-1, SULFATE ION, ...
著者Nam, Y.W, Zhang, M.
登録日2018-04-09
公開日2018-08-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model.
Sci Rep, 8, 2018
1F3C
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REFINED SOLUTION STRUCTURE OF 8KDA DYNEIN LIGHT CHAIN (DLC8)
分子名称: DYNEIN
著者Fan, J.-S, Zhang, Q, Tochio, H, Zhang, M.
登録日2000-06-02
公開日2001-02-28
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Structural basis of diverse sequence-dependent target recognition by the 8 kDa dynein light chain.
J.Mol.Biol., 306, 2001
8I3E
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Crystal structure of ELKS1 in complex with Piccolo
分子名称: ELKS/Rab6-interacting/CAST family member 1, MKIAA0559 protein
著者Cai, Q, Zhang, M.
登録日2023-01-17
公開日2024-01-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Short-distance vesicle transport via phase separation.
Cell, 187, 2024
3WB8
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Crystal Structure of MyoVa-GTD
分子名称: 1,2-ETHANEDIOL, Unconventional myosin-Va
著者Wei, Z, Liu, X, Yu, C, Zhang, M.
登録日2013-05-13
公開日2013-07-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.499 Å)
主引用文献Structural basis of cargo recognitions for class V myosins
Proc.Natl.Acad.Sci.USA, 110, 2013
7DJZ
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Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M.
登録日2020-11-22
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.397 Å)
主引用文献Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Commun Biol, 5, 2022
7DK0
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Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, MW05 heavy chain, MW05 light chain, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M.
登録日2020-11-22
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.199 Å)
主引用文献Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction.
Commun Biol, 5, 2022
6GQD
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BU of 6gqd by Molmil
Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L
分子名称: 1,2-ETHANEDIOL, 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, Galactose-1-phosphate uridylyltransferase, ...
著者Fairhead, M, Strain-Damerell, C, Kopec, J, Bezerra, G.A, Zhang, M, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W, Structural Genomics Consortium (SGC)
登録日2018-06-07
公開日2018-07-18
実験手法X-RAY DIFFRACTION (1.523 Å)
主引用文献Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L
To Be Published
2ADZ
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solution structure of the joined PH domain of alpha1-syntrophin
分子名称: Alpha-1-syntrophin
著者Yan, J, Wen, W, Xu, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M.
登録日2005-07-21
公開日2006-01-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
1Z86
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Solution structure of the PDZ domain of alpha-syntrophin
分子名称: Alpha-1-syntrophin
著者Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M.
登録日2005-03-30
公開日2006-01-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
3WYO
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BU of 3wyo by Molmil
Heterodimeric myoglobin formed by domain swapping
分子名称: Myoglobin, PROTOPORPHYRIN IX CONTAINING FE
著者Lin, Y.W, Nagao, S, Zhang, M, Shomura, Y, Higuchi, Y, Hirota, S.
登録日2014-09-04
公開日2014-11-19
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Rational design of heterodimeric protein using domain swapping for myoglobin.
Angew.Chem.Int.Ed.Engl., 54, 2015
1Y76
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Solution Structure of Patj/Pals1 L27 Domain Complex
分子名称: MAGUK p55 subfamily member 5, protein associated to tight junctions
著者Feng, W, Long, J.-F, Zhang, M.
登録日2004-12-08
公開日2005-04-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins.
Proc.Natl.Acad.Sci.Usa, 102, 2005
1Y74
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Solution Structure of mLin-2/mLin-7 L27 Domain Complex
分子名称: Peripheral plasma membrane protein CASK, lin 7 homolog b
著者Feng, W, Long, J.-F, Zhang, M.
登録日2004-12-08
公開日2005-04-19
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins.
Proc.Natl.Acad.Sci.Usa, 102, 2005
3WP1
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Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
分子名称: Disks large homolog 4, Lethal(2) giant larvae protein homolog 2, SULFATE ION
著者Zhu, J, Shang, Y, Wan, Q, Xia, Y, Chen, J, Du, Q, Zhang, M.
登録日2014-01-08
公開日2014-03-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
Cell Res., 24, 2014
3WP0
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Crystal structure of Dlg GK in complex with a phosphor-Lgl2 peptide
分子名称: Disks large homolog 4, GLYCEROL, Lethal(2) giant larvae protein homolog 2
著者Zhu, J, Shang, Y, Wan, Q, Xia, Y, Chen, J, Du, Q, Zhang, M.
登録日2014-01-08
公開日2014-03-19
最終更新日2014-04-30
実験手法X-RAY DIFFRACTION (2.039 Å)
主引用文献Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl
Cell Res., 24, 2014
2B8K
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12-subunit RNA Polymerase II
分子名称: DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ...
著者Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J.
登録日2005-10-07
公開日2006-06-20
最終更新日2012-06-13
実験手法X-RAY DIFFRACTION (4.15 Å)
主引用文献Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model.
Structure, 14, 2006
1Z87
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solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin
分子名称: Alpha-1-syntrophin
著者Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M.
登録日2005-03-30
公開日2006-01-24
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin
Embo J., 24, 2005
7XJF
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Crystal structure of 6MW3211 Fab in complex with CD47
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ...
著者Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M, Wang, M.
登録日2022-04-16
公開日2023-05-31
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment.
Theranostics, 13, 2023
7DPM
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Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ...
著者Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M.
登録日2020-12-20
公開日2021-02-17
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.304 Å)
主引用文献Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV.
Mabs, 13, 2021

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