3CYY
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5IH4
| Human Casein Kinase 1 isoform delta apo (kinase domain) | 分子名称: | Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, SULFATE ION, ... | 著者 | Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H. | 登録日 | 2016-02-29 | 公開日 | 2016-04-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol, 23, 2016
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6ALE
| A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model | 分子名称: | (3E)-6,7-dichloro-3-(hydroxyimino)-1,3-dihydro-2H-indol-2-one, CALCIUM ION, Calmodulin-2, ... | 著者 | Nam, Y.W, Zhang, M. | 登録日 | 2017-08-07 | 公開日 | 2018-08-08 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model. Sci Rep, 8, 2018
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5IH6
| Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A derivative | 分子名称: | 6-(3-bromophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ... | 著者 | Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H. | 登録日 | 2016-02-29 | 公開日 | 2016-04-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol, 23, 2016
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6CU7
| Alpha Synuclein fibril formed by full length protein - Rod Polymorph | 分子名称: | Alpha-synuclein | 著者 | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | 登録日 | 2018-03-23 | 公開日 | 2018-09-12 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | 主引用文献 | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9, 2018
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5IH5
| Human Casein Kinase 1 isoform delta (kinase domain) in complex with Epiblastin A | 分子名称: | 6-(3-chlorophenyl)pteridine-2,4,7-triamine, Casein kinase I isoform delta, S,R MESO-TARTARIC ACID, ... | 著者 | Ursu, A, Illich, D.J, Takemoto, Y, Porfetye, A.T, Zhang, M, Brockmeyer, A, Janning, P, Watanabe, N, Osada, H, Vetter, I.R, Ziegler, S, Schoeler, H.R, Waldmann, H. | 登録日 | 2016-02-29 | 公開日 | 2016-04-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Epiblastin A Induces Reprogramming of Epiblast Stem Cells Into Embryonic Stem Cells by Inhibition of Casein Kinase 1. Cell Chem Biol, 23, 2016
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6CU8
| Alpha Synuclein fibril formed by full length protein - Twister Polymorph | 分子名称: | Alpha-synuclein | 著者 | Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L. | 登録日 | 2018-03-23 | 公開日 | 2018-09-12 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel. Nat Commun, 9, 2018
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6CZQ
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1F3C
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8I3E
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3WB8
| Crystal Structure of MyoVa-GTD | 分子名称: | 1,2-ETHANEDIOL, Unconventional myosin-Va | 著者 | Wei, Z, Liu, X, Yu, C, Zhang, M. | 登録日 | 2013-05-13 | 公開日 | 2013-07-10 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.499 Å) | 主引用文献 | Structural basis of cargo recognitions for class V myosins Proc.Natl.Acad.Sci.USA, 110, 2013
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7DJZ
| Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ... | 著者 | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | 登録日 | 2020-11-22 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | 主引用文献 | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction. Commun Biol, 5, 2022
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7DK0
| Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MW05 heavy chain, MW05 light chain, ... | 著者 | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | 登録日 | 2020-11-22 | 公開日 | 2021-06-09 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.199 Å) | 主引用文献 | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction. Commun Biol, 5, 2022
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6GQD
| Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L | 分子名称: | 1,2-ETHANEDIOL, 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, Galactose-1-phosphate uridylyltransferase, ... | 著者 | Fairhead, M, Strain-Damerell, C, Kopec, J, Bezerra, G.A, Zhang, M, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W, Structural Genomics Consortium (SGC) | 登録日 | 2018-06-07 | 公開日 | 2018-07-18 | 実験手法 | X-RAY DIFFRACTION (1.523 Å) | 主引用文献 | Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L To Be Published
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2ADZ
| solution structure of the joined PH domain of alpha1-syntrophin | 分子名称: | Alpha-1-syntrophin | 著者 | Yan, J, Wen, W, Xu, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M. | 登録日 | 2005-07-21 | 公開日 | 2006-01-24 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin Embo J., 24, 2005
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1Z86
| Solution structure of the PDZ domain of alpha-syntrophin | 分子名称: | Alpha-1-syntrophin | 著者 | Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M. | 登録日 | 2005-03-30 | 公開日 | 2006-01-24 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin Embo J., 24, 2005
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3WYO
| Heterodimeric myoglobin formed by domain swapping | 分子名称: | Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Lin, Y.W, Nagao, S, Zhang, M, Shomura, Y, Higuchi, Y, Hirota, S. | 登録日 | 2014-09-04 | 公開日 | 2014-11-19 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Rational design of heterodimeric protein using domain swapping for myoglobin. Angew.Chem.Int.Ed.Engl., 54, 2015
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1Y76
| Solution Structure of Patj/Pals1 L27 Domain Complex | 分子名称: | MAGUK p55 subfamily member 5, protein associated to tight junctions | 著者 | Feng, W, Long, J.-F, Zhang, M. | 登録日 | 2004-12-08 | 公開日 | 2005-04-19 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A unified assembly mode revealed by the structures of tetrameric L27 domain complexes formed by mLin-2/mLin-7 and Patj/Pals1 scaffold proteins. Proc.Natl.Acad.Sci.Usa, 102, 2005
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1Y74
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3WP1
| Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl | 分子名称: | Disks large homolog 4, Lethal(2) giant larvae protein homolog 2, SULFATE ION | 著者 | Zhu, J, Shang, Y, Wan, Q, Xia, Y, Chen, J, Du, Q, Zhang, M. | 登録日 | 2014-01-08 | 公開日 | 2014-03-19 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (2.804 Å) | 主引用文献 | Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl Cell Res., 24, 2014
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3WP0
| Crystal structure of Dlg GK in complex with a phosphor-Lgl2 peptide | 分子名称: | Disks large homolog 4, GLYCEROL, Lethal(2) giant larvae protein homolog 2 | 著者 | Zhu, J, Shang, Y, Wan, Q, Xia, Y, Chen, J, Du, Q, Zhang, M. | 登録日 | 2014-01-08 | 公開日 | 2014-03-19 | 最終更新日 | 2014-04-30 | 実験手法 | X-RAY DIFFRACTION (2.039 Å) | 主引用文献 | Phosphorylation-dependent interaction between tumor suppressors Dlg and Lgl Cell Res., 24, 2014
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2B8K
| 12-subunit RNA Polymerase II | 分子名称: | DNA-directed RNA polymerase II 13.6 kDa polypeptide, DNA-directed RNA polymerase II 140 kDa polypeptide, DNA-directed RNA polymerase II 19 kDa polypeptide, ... | 著者 | Meyer, P.A, Ye, P, Zhang, M, Suh, M.H, Fu, J. | 登録日 | 2005-10-07 | 公開日 | 2006-06-20 | 最終更新日 | 2012-06-13 | 実験手法 | X-RAY DIFFRACTION (4.15 Å) | 主引用文献 | Phasing RNA Polymerase II Using Intrinsically Bound Zn Atoms: An Updated Structural Model. Structure, 14, 2006
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1Z87
| solution structure of the split PH-PDZ Supramodule of alpha-Syntrophin | 分子名称: | Alpha-1-syntrophin | 著者 | Yan, J, Xu, W, Wen, W, Long, J.F, Adams, M.E, Froehner, S.C, Zhang, M. | 登録日 | 2005-03-30 | 公開日 | 2006-01-24 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the split PH domain and distinct lipid-binding properties of the PH-PDZ supramodule of alpha-syntrophin Embo J., 24, 2005
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7XJF
| Crystal structure of 6MW3211 Fab in complex with CD47 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M, Wang, M. | 登録日 | 2022-04-16 | 公開日 | 2023-05-31 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment. Theranostics, 13, 2023
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7DPM
| Crystal structure of SARS-CoV-2 Spike RBD in complex with MW06 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Spike protein S1, ... | 著者 | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | 登録日 | 2020-12-20 | 公開日 | 2021-02-17 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.304 Å) | 主引用文献 | Characterization of MW06, a human monoclonal antibody with cross-neutralization activity against both SARS-CoV-2 and SARS-CoV. Mabs, 13, 2021
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