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PDB: 418 件

6CZQ
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A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C. elegans ALS model
分子名称: CALCIUM ION, Calmodulin-1, SULFATE ION, ...
著者Nam, Y.W, Zhang, M.
登録日2018-04-09
公開日2018-08-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献A V-to-F substitution in SK2 channels causes Ca2+hypersensitivity and improves locomotion in a C. elegans ALS model.
Sci Rep, 8, 2018
8I3E
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Crystal structure of ELKS1 in complex with Piccolo
分子名称: ELKS/Rab6-interacting/CAST family member 1, MKIAA0559 protein
著者Cai, Q, Zhang, M.
登録日2023-01-17
公開日2024-01-24
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Short-distance vesicle transport via phase separation.
Cell, 187, 2024
6Q91
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Structure of human galactokinase 1 bound with 5-Chloro-N-isobutyl-2-methoxybenzamide
分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, 5-chloranyl-2-methoxy-~{N}-(2-methylpropyl)benzamide, Galactokinase, ...
著者Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W.
登録日2018-12-17
公開日2019-01-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of human galactokinase 1 bound with 5-Chloro-N-isobutyl-2-methoxybenzamide
To Be Published
6Q8Z
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Structure of human galactokinase 1 bound with N-(Cyclobutylmethyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide
分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ...
著者Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W.
登録日2018-12-16
公開日2019-01-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of human galactokinase 1 bound with N-(Cyclobutylmethyl)-1,5-dimethyl-1H-pyrazole-4-carboxamide
To Be Published
6Q3W
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Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate
分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, beta-D-galactopyranose, ...
著者Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W.
登録日2018-12-04
公開日2019-01-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.962 Å)
主引用文献Structure of human galactokinase 1 bound with Ethyl 1-(2-pyrazinyl)-4-piperidinecarboxylate
To Be Published
5YPO
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BU of 5ypo by Molmil
Crystal structure of PSD-95 GK domain in complex with phospho-SAPAP peptide
分子名称: Disks large homolog 4, GLYCEROL, SAPAP
著者Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhang, R, Zhang, M.
登録日2017-11-02
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Cell Rep, 21, 2017
6QJE
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BU of 6qje by Molmil
Structure of human galactokinase 1 bound with 4-{[2-(Methylsulfonyl)-1H-imidazol-1-yl]methyl}-1,3-thiazole
分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, 4-[(2-methylsulfonylimidazol-1-yl)methyl]-1,3-thiazole, Galactokinase, ...
著者Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W.
登録日2019-01-24
公開日2019-02-27
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of human galactokinase 1 bound with 4-{[2-(Methylsulfonyl)-1H-imidazol-1-yl]methyl}-1,3-thiazole
To Be Published
6Q90
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BU of 6q90 by Molmil
Structure of human galactokinase 1 bound with 1-(4-Methoxyphenyl)-3-(4-pyridinyl)urea
分子名称: 2-(1,3-benzoxazol-2-ylamino)spiro[1,6,7,8-tetrahydroquinazoline-4,1'-cyclohexane]-5-one, Galactokinase, N-(4-methoxyphenyl)-N'-pyridin-4-ylurea, ...
著者Mackinnon, S.R, Bezerra, G.A, Zhang, M, Foster, W, Krojer, T, Brandao-Neto, J, Douangamath, A, Arrowsmith, C, Edwards, A, Bountra, C, Brennan, P, Lai, K, Yue, W.W.
登録日2018-12-16
公開日2019-01-23
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of human galactokinase 1 bound with 1-(4-Methoxyphenyl)-3-(4-pyridinyl)urea
To Be Published
1SDR
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BU of 1sdr by Molmil
CRYSTAL STRUCTURE OF AN RNA DODECAMER CONTAINING THE ESCHERICHIA COLI SHINE-DALGARNO SEQUENCE
分子名称: RNA (5'-R(*AP*UP*CP*AP*CP*CP*UP*CP*CP*UP*UP*A)-3'), RNA (5'-R(*UP*AP*AP*GP*GP*AP*GP*GP*UP*GP*AP*U)-3')
著者Schindelin, H, Zhang, M, Bald, R, Fuerste, J.-P, Erdmann, V.A, Heinemann, U.
登録日1994-12-11
公開日1995-02-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of an RNA dodecamer containing the Escherichia coli Shine-Dalgarno sequence.
J.Mol.Biol., 249, 1995
4FYP
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BU of 4fyp by Molmil
Crystal Structure of Plant Vegetative Storage Protein
分子名称: MAGNESIUM ION, Vegetative storage protein 1
著者Chen, Y, Wei, J, Wang, M, Gong, W, Zhang, M.
登録日2012-07-05
公開日2013-06-26
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of Arabidopsis VSP1 reveals the plant class C-like phosphatase structure of the DDDD superfamily of phosphohydrolases
Plos One, 7, 2012
2WCO
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BU of 2wco by Molmil
Structures of the Streptomyces coelicolor A3(2) Hyaluronan Lyase in Complex with Oligosaccharide Substrates and an Inhibitor
分子名称: 4-deoxy-beta-D-glucopyranuronic acid-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose, FORMIC ACID, GLYCEROL, ...
著者Elmabrouk, Z.H, Taylor, E.J, Vincent, F, Smith, N.L, Zhang, M, Charnock, S.J, Turkenburg, J.P, Davies, G.J, Black, G.W.
登録日2009-03-12
公開日2010-08-18
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Crystal Structures of a Family 8 Polysaccharide Lyase Reveal Open and Highly Occluded Substrate-Binding Cleft Conformations.
Proteins, 79, 2011
4G5S
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BU of 4g5s by Molmil
Structure of LGN GL3/Galphai3 complex
分子名称: CITRIC ACID, G-protein-signaling modulator 2, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jia, M, Li, J, Zhu, J, Wen, W, Zhang, M, Wang, W.
登録日2012-07-18
公開日2012-09-05
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (3.62 Å)
主引用文献Crystal Structures of the scaffolding protein LGN reveal the general mechanism by which GoLoco binding motifs inhibit the release of GDP from Galphai subunits in G-coupled heterotrimeric proteins
To be Published
6CU7
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BU of 6cu7 by Molmil
Alpha Synuclein fibril formed by full length protein - Rod Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
6CU8
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BU of 6cu8 by Molmil
Alpha Synuclein fibril formed by full length protein - Twister Polymorph
分子名称: Alpha-synuclein
著者Li, B, Hatami, A, Ge, P, Murray, K.A, Sheth, P, Zhang, M, Nair, G, Sawaya, M.R, Zhu, C, Broad, M, Shin, W.S, Ye, S, John, V, Eisenberg, D.S, Zhou, Z.H, Jiang, L.
登録日2018-03-23
公開日2018-09-12
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Cryo-EM of full-length alpha-synuclein reveals fibril polymorphs with a common structural kernel.
Nat Commun, 9, 2018
5YPR
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BU of 5ypr by Molmil
Crystal Structure of PSD-95 SH3-GK domain in complex with a synthesized inhibitor
分子名称: Disks large homolog 4, Synthesized GK inhibitor
著者Zhu, J, Zhou, Q, Shang, Y, Weng, Z, Zhu, R, Zhang, M.
登録日2017-11-02
公開日2018-03-14
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.349 Å)
主引用文献Synaptic Targeting and Function of SAPAPs Mediated by Phosphorylation-Dependent Binding to PSD-95 MAGUKs.
Cell Rep, 21, 2017
2HQ4
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BU of 2hq4 by Molmil
Crystal Structure of ORF 1580 a hypothetical protein from Pyrococcus horikoshii
分子名称: Hypothetical protein PH1570
著者Li, Y, Marshall, M, Chang, J, Zhao, M, Zhang, M, Xu, H, Liu, Z.J, Rose, J.P, Wang, B.C, Southeast Collaboratory for Structural Genomics, Southeast Collaboratory for Structural Genomics (SECSG)
登録日2006-07-18
公開日2006-09-19
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal Structure of ORF 1580 a hypothetical protein from Pyrococcus horikoshii
To be Published
2LSR
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BU of 2lsr by Molmil
Solution structure of harmonin N terminal domain in complex with a exon68 encoded peptide of cadherin23
分子名称: Harmonin, peptide from Cadherin-23
著者Pan, L, Wu, L, Zhang, C, Zhang, M.
登録日2012-05-04
公開日2012-08-15
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献Large protein assemblies formed by multivalent interactions between cadherin23 and harmonin suggest a stable anchorage structure at the tip link of stereocilia.
J.Biol.Chem., 287, 2012
2FQD
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BU of 2fqd by Molmil
Crystal Structures of E. coli Laccase CueO under different copper binding situations
分子名称: Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ...
著者Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W.
登録日2006-01-18
公開日2007-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of E. coli laccase CueO at different copper concentrations.
Biochem.Biophys.Res.Commun., 354, 2007
2FQE
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BU of 2fqe by Molmil
Crystal Structures of E. coli Laccase CueO under different copper binding situations
分子名称: Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ...
著者Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W.
登録日2006-01-18
公開日2007-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Crystal structures of E. coli laccase CueO at different copper concentrations.
Biochem.Biophys.Res.Commun., 354, 2007
2FQG
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BU of 2fqg by Molmil
Crystal Structures of E. coli Laccase CueO under different copper binding situations
分子名称: Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ...
著者Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W.
登録日2006-01-18
公開日2007-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structures of E. coli laccase CueO at different copper concentrations.
Biochem.Biophys.Res.Commun., 354, 2007
2FQF
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BU of 2fqf by Molmil
Crystal Structures of E. coli Laccase CueO under different copper binding situations
分子名称: Blue copper oxidase cueO, CITRIC ACID, COPPER (II) ION, ...
著者Li, X, Wei, Z, Zhang, M, Teng, M, Gong, W.
登録日2006-01-18
公開日2007-01-30
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of E. coli laccase CueO at different copper concentrations.
Biochem.Biophys.Res.Commun., 354, 2007
5B64
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BU of 5b64 by Molmil
A novel binding mode of MAGUK GK domain revealed by DLG GK domain in complex with KIF13B MBS domain
分子名称: DLG GK, GLYCEROL, Protein Kif13b, ...
著者Shang, Y, Zhu, J, Zhang, M.
登録日2016-05-24
公開日2016-10-12
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An Atypical MAGUK GK Target Recognition Mode Revealed by the Interaction between DLG and KIF13B
Structure, 24, 2016
7XE4
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BU of 7xe4 by Molmil
structure of a membrane-bound glycosyltransferase
分子名称: (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hu, X.L, Yang, P, Zhang, M, Liu, X.T, Yu, H.J.
登録日2022-03-29
公開日2023-03-29
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structural and mechanistic insights into fungal beta-1,3-glucan synthase FKS1.
Nature, 616, 2023
8YM2
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BU of 8ym2 by Molmil
Crystal structure of AIDA-1 PTB domain in complex with SynGAP NPxF motif
分子名称: Ankyrin repeat and sterile alpha motif domain-containing protein 1B, Ras/Rap GTPase-activating protein SynGAP
著者Wang, X, Wang, Y, Cai, Q, Zhang, M.
登録日2024-03-08
公開日2024-05-29
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献AIDA-1/ANKS1B Binds to the SynGAP Family RasGAPs with High Affinity and Specificity.
J.Mol.Biol., 436, 2024
7YUY
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BU of 7yuy by Molmil
Structure of a mutated membrane-bound glycosyltransferase
分子名称: (11R,14S)-17-amino-14-hydroxy-8,14-dioxo-9,13,15-trioxa-14lambda~5~-phosphaheptadecan-11-yl decanoate, 1,3-beta-glucan synthase component FKS1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Hu, X.L, Yang, P, Zhang, M, Liu, X.T, Yu, H.J.
登録日2022-08-18
公開日2023-03-29
最終更新日2023-04-19
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural and mechanistic insights into fungal beta-1,3-glucan synthase FKS1.
Nature, 616, 2023

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