6LYW
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![BU of 6lyw by Molmil](/molmil-images/mine/6lyw) | Structural insight into the biological functions of Arabidopsis thaliana ACHT1 | Descriptor: | GLYCEROL, SULFATE ION, Thioredoxin-like 2-1, ... | Authors: | Wang, J.C, Pan, W.M, Wang, M.Z, Zhang, M. | Deposit date: | 2020-02-16 | Release date: | 2020-05-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Structural insight into the biological functions of Arabidopsis thaliana ACHT1. Int.J.Biol.Macromol., 158, 2020
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8WJY
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![BU of 8wjy by Molmil](/molmil-images/mine/8wjy) | PKMYT1_Cocrystal_Cpd 4 | Descriptor: | DIMETHYL SULFOXIDE, GLYCEROL, Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase, ... | Authors: | Wang, Y, Wang, C, Liu, T, Qi, H, Chen, S, Cai, X, Zhang, M, Aliper, A, Ren, F, Ding, X, Zhavoronkov, A. | Deposit date: | 2023-09-26 | Release date: | 2023-11-22 | Last modified: | 2024-05-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Discovery of Tetrahydropyrazolopyrazine Derivatives as Potent and Selective MYT1 Inhibitors for the Treatment of Cancer. J.Med.Chem., 67, 2024
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2OGP
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![BU of 2ogp by Molmil](/molmil-images/mine/2ogp) | Solution structure of the second PDZ domain of Par-3 | Descriptor: | Partitioning-defective 3 homolog | Authors: | Feng, W, Wu, H, Chen, J, Chan, L.-N, Zhang, M. | Deposit date: | 2007-01-07 | Release date: | 2007-12-25 | Last modified: | 2023-12-27 | Method: | SOLUTION NMR | Cite: | PDZ domains of par-3 as potential phosphoinositide signaling integrators Mol.Cell, 28, 2007
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2PKU
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![BU of 2pku by Molmil](/molmil-images/mine/2pku) | Solution structure of PICK1 PDZ in complex with the carboxyl tail peptide of GluR2 | Descriptor: | PRKCA-binding protein, peptide (GLU)(SER)(VAL)(LYS)(ILE) | Authors: | Pan, L, Wu, H, Shen, C, Shi, Y, Xia, J, Zhang, M. | Deposit date: | 2007-04-18 | Release date: | 2007-11-20 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes Embo J., 26, 2007
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6JVY
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![BU of 6jvy by Molmil](/molmil-images/mine/6jvy) | Crystal structure of RBM38 in complex with single-stranded DNA | Descriptor: | DNA (5'-D(*TP*GP*TP*GP*TP*GP*TP*GP*TP*GP*TP*G)-3'), RNA-binding protein 38, SULFATE ION | Authors: | Qian, K, Li, M, Wang, J, Zhang, M, Wang, M. | Deposit date: | 2019-04-17 | Release date: | 2020-01-01 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Structural basis for mRNA recognition by human RBM38. Biochem.J., 477, 2020
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2PON
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![BU of 2pon by Molmil](/molmil-images/mine/2pon) | Solution structure of the Bcl-xL/Beclin-1 complex | Descriptor: | Apoptosis regulator Bcl-X, Beclin-1 | Authors: | Feng, W, Huang, S, Wu, H, Zhang, M. | Deposit date: | 2007-04-27 | Release date: | 2007-09-04 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Molecular Basis of Bcl-xL's Target Recognition Versatility Revealed by the Structure of Bcl-xL in Complex with the BH3 Domain of Beclin-1. J.Mol.Biol., 372, 2007
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6JEA
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![BU of 6jea by Molmil](/molmil-images/mine/6jea) | crystal structure of a beta-N-acetylhexosaminidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-N-acetylhexosaminidase, ZINC ION | Authors: | Chen, X, Wang, J.C, Liu, M.J, Yang, W.Y, Wang, Y.Z, Tang, R.P, Zhang, M. | Deposit date: | 2019-02-04 | Release date: | 2019-03-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.275 Å) | Cite: | Crystallographic evidence for substrate-assisted catalysis of beta-N-acetylhexosaminidas from Akkermansia muciniphila. Biochem. Biophys. Res. Commun., 511, 2019
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6JE8
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![BU of 6je8 by Molmil](/molmil-images/mine/6je8) | crystal structure of a beta-N-acetylhexosaminidase | Descriptor: | Beta-N-acetylhexosaminidase, FORMIC ACID, GLYCEROL, ... | Authors: | Chen, X, Wang, J.C, Liu, M.J, Yang, W.Y, Wang, Y.Z, Tang, R.P, Zhang, M. | Deposit date: | 2019-02-04 | Release date: | 2019-03-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.798 Å) | Cite: | Crystallographic evidence for substrate-assisted catalysis of beta-N-acetylhexosaminidas from Akkermansia muciniphila. Biochem. Biophys. Res. Commun., 511, 2019
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2K1Z
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6JEB
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![BU of 6jeb by Molmil](/molmil-images/mine/6jeb) | crystal structure of a beta-N-acetylhexosaminidase | Descriptor: | ACETAMIDE, Beta-N-acetylhexosaminidase, ZINC ION | Authors: | Chen, X, Wang, J.C, Liu, M.J, Yang, W.Y, Wang, Y.Z, Tang, R.P, Zhang, M. | Deposit date: | 2019-02-05 | Release date: | 2019-03-13 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.498 Å) | Cite: | Crystallographic evidence for substrate-assisted catalysis of beta-N-acetylhexosaminidas from Akkermansia muciniphila. Biochem. Biophys. Res. Commun., 511, 2019
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2FZ0
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![BU of 2fz0 by Molmil](/molmil-images/mine/2fz0) | Identification of yeast R-SNARE Nyv1p as a novel longin domain protein | Descriptor: | v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane; Nyv1p | Authors: | Wen, W, Zhang, M. | Deposit date: | 2006-02-08 | Release date: | 2006-03-07 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Identification of the Yeast R-SNARE Nyv1p as a Novel Longin Domain-containing Protein Mol.Cell.Biol., 17, 2006
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2K20
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![BU of 2k20 by Molmil](/molmil-images/mine/2k20) | |
2KBS
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![BU of 2kbs by Molmil](/molmil-images/mine/2kbs) | Solution structure of harmonin PDZ2 in complex with the carboxyl tail peptide of cadherin23 | Descriptor: | Harmonin, octameric peptide from Cadherin-23 | Authors: | Pan, L, Yan, J, Wu, L, Zhang, M. | Deposit date: | 2008-12-05 | Release date: | 2009-03-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23 Proc.Natl.Acad.Sci.USA, 106, 2009
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2KBR
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![BU of 2kbr by Molmil](/molmil-images/mine/2kbr) | Solution structure of harmonin N terminal domain in complex with a internal peptide of cadherin23 | Descriptor: | 18-meric peptide from Cadherin-23, Harmonin | Authors: | Pan, L, Yan, J, Wu, L, Zhang, M. | Deposit date: | 2008-12-05 | Release date: | 2009-03-31 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Assembling stable hair cell tip link complex via multidentate interactions between harmonin and cadherin 23 Proc.Natl.Acad.Sci.USA, 106, 2009
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2KIA
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![BU of 2kia by Molmil](/molmil-images/mine/2kia) | Solution structure of Myosin VI C-terminal cargo-binding domain | Descriptor: | Myosin-VI | Authors: | Feng, W, Yu, C, Wei, Z, Miyanoiri, Y, Zhang, M. | Deposit date: | 2009-04-29 | Release date: | 2009-09-29 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Myosin VI undergoes cargo-mediated dimerization Cell(Cambridge,Mass.), 138, 2009
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2KXS
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![BU of 2kxs by Molmil](/molmil-images/mine/2kxs) | ZO1 ZU5 domain in complex with GRINL1A peptide | Descriptor: | Tight junction protein ZO-1,Myocardial zonula adherens protein | Authors: | Wen, W, Zhang, M. | Deposit date: | 2010-05-12 | Release date: | 2011-03-30 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | Cdc42-dependent formation of the ZO-1/MRCKb complex at the leading edge controls cell migration Embo J., 30, 2011
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6GQD
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![BU of 6gqd by Molmil](/molmil-images/mine/6gqd) | Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L | Descriptor: | 1,2-ETHANEDIOL, 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, Galactose-1-phosphate uridylyltransferase, ... | Authors: | Fairhead, M, Strain-Damerell, C, Kopec, J, Bezerra, G.A, Zhang, M, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W, Structural Genomics Consortium (SGC) | Deposit date: | 2018-06-07 | Release date: | 2018-07-18 | Method: | X-RAY DIFFRACTION (1.523 Å) | Cite: | Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L To Be Published
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3SBJ
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![BU of 3sbj by Molmil](/molmil-images/mine/3sbj) | MutM slanted complex 7 | Descriptor: | 5'-D(*GP*GP*TP*AP*GP*AP*CP*CP*AP*GP*G)-3', 5'-D(P*CP*CP*TP*GP*GP*TP*(CX)P*TP*AP*CP*C)-3', Formamidopyrimidine-DNA glycosylase, ... | Authors: | Sung, R.J, Zhang, M, Verdine, G.L. | Deposit date: | 2011-06-05 | Release date: | 2012-01-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Strandwise translocation of a DNA glycosylase on undamaged DNA. Proc.Natl.Acad.Sci.USA, 109, 2012
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7XJF
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![BU of 7xjf by Molmil](/molmil-images/mine/7xjf) | Crystal structure of 6MW3211 Fab in complex with CD47 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | Authors: | Wang, J, Wang, R, Jiao, S, Wang, S, Zhang, J, Zhang, M, Wang, M. | Deposit date: | 2022-04-16 | Release date: | 2023-05-31 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Blockade of dual immune checkpoint inhibitory signals with a CD47/PD-L1 bispecific antibody for cancer treatment. Theranostics, 13, 2023
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7DK0
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![BU of 7dk0 by Molmil](/molmil-images/mine/7dk0) | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW05 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, MW05 heavy chain, MW05 light chain, ... | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | Deposit date: | 2020-11-22 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.199 Å) | Cite: | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction. Commun Biol, 5, 2022
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7DJZ
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![BU of 7djz by Molmil](/molmil-images/mine/7djz) | Crystal structure of SARS-CoV-2 Spike RBD in complex with MW01 Fab | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CITRIC ACID, MW01 heavy chain, ... | Authors: | Wang, J, Jiao, S, Wang, R, Zhang, J, Zhang, M, Wang, M. | Deposit date: | 2020-11-22 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.397 Å) | Cite: | Antibody-dependent enhancement (ADE) of SARS-CoV-2 pseudoviral infection requires Fc gamma RIIB and virus-antibody complex with bivalent interaction. Commun Biol, 5, 2022
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6IRR
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![BU of 6irr by Molmil](/molmil-images/mine/6irr) | Solution structure of DISC1/ATF4 complex | Descriptor: | Disrupted in schizophrenia 1 homolog,Cyclic AMP-dependent transcription factor ATF-4 | Authors: | Ye, F, Yu, C, Zhang, M. | Deposit date: | 2018-11-14 | Release date: | 2019-09-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural interaction between DISC1 and ATF4 underlying transcriptional and synaptic dysregulation in an iPSC model of mental disorders. Mol. Psychiatry, 2019
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6M3R
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![BU of 6m3r by Molmil](/molmil-images/mine/6m3r) | Crystal structure of AnkG/beta4-spectrin complex | Descriptor: | Ankyrin-3, Spectrin beta chain | Authors: | Li, J, Chen, K, Zhu, R, Zhang, M. | Deposit date: | 2020-03-04 | Release date: | 2020-05-13 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4.313 Å) | Cite: | Structural Basis Underlying Strong Interactions between Ankyrins and Spectrins. J.Mol.Biol., 432, 2020
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7W3X
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![BU of 7w3x by Molmil](/molmil-images/mine/7w3x) | Cryo-EM structure of plant receptor like protein RXEG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Membrane-localized LRR receptor-like protein, ... | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | Deposit date: | 2021-11-26 | Release date: | 2022-06-22 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.21 Å) | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature, 610, 2022
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7W3V
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![BU of 7w3v by Molmil](/molmil-images/mine/7w3v) | Plant receptor like protein RXEG1 in complex with xyloglucanase XEG1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Cell 12A endoglucanase, ... | Authors: | Sun, Y, Wang, Y, Zhang, X.X, Chen, Z.D, Xia, Y.Q, Sun, Y.J, Zhang, M.M, Xiao, Y, Han, Z.F, Wang, Y.C, Chai, J.J. | Deposit date: | 2021-11-26 | Release date: | 2022-06-22 | Last modified: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.11 Å) | Cite: | Plant receptor-like protein activation by a microbial glycoside hydrolase. Nature, 610, 2022
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