2PON

Solution structure of the Bcl-xL/Beclin-1 complex

Summary for 2PON

• Entry DOI: 10.2210/pdb2pon/pdb
• Descriptor: Beclin-1, Apoptosis regulator Bcl-X (2 entities in total)
• Functional Keywords: apoptosis; autophagy; bcl-2 family proteins; beclin-1, apoptosis inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein: Q14457; Mitochondrion membrane; Single-pass membrane protein (By similarity): Q07817
• Total number of polymer chains: 2
• Total formula weight: 20398.60

Authors

Feng, W.,Huang, S.,Wu, H.,Zhang, M. (deposition date: 2007-04-27, release date: 2007-09-04, Last modification date: 2022-03-16)

• Primary citation: Feng, W.,Huang, S.,Wu, H.,Zhang, M.; Molecular Basis of Bcl-xL's Target Recognition Versatility Revealed by the Structure of Bcl-xL in Complex with the BH3 Domain of Beclin-1.; J.Mol.Biol., 372:223-235, 2007; PubMed: 17659302; DOI: 10.1016/j.jmb.2007.06.069

Experimental method

SOLUTION NMR