4GFV
 
 | | PTPN18 in complex with HER2-pY1196 phosphor-peptides | | 分子名称: | HER2-pY1196 phosphor-peptide, Tyrosine-protein phosphatase non-receptor type 18 | | 著者 | Wang, H.M, Yang, F, Du, Y.J, Yang, D.X, Zhang, Y, Yu, X, Sun, J.P. | | 登録日 | 2012-08-04 | | 公開日 | 2013-10-23 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.095 Å) | | 主引用文献 | PTPN18-HER2 peptides
To be Published
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8IMZ
 | | Cryo-EM structure of mouse Piezo1-MDFIC complex (composite map) | | 分子名称: | MyoD family inhibitor domain-containing protein, Piezo-type mechanosensitive ion channel component 1 | | 著者 | Zhou, Z, Ma, X, Lin, Y, Cheng, D, Bavi, N, Li, J.V, Sutton, D, Yao, M, Harvey, N, Corry, B, Zhang, Y, Cox, C.D. | | 登録日 | 2023-03-07 | | 公開日 | 2023-08-09 | | 最終更新日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (3.66 Å) | | 主引用文献 | MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels.
Science, 381, 2023
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6JCX
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6IEX
 | | Crystal structure of HLA-B*4001 in complex with SARS-CoV derived peptide N216-225 GETALALLLL | | 分子名称: | Beta-2-microglobulin, GLY-GLU-THR-ALA-LEU-ALA-LEU-LEU-LEU-LEU, MHC class I antigen | | 著者 | Ji, W, Niu, L, Peng, W, Zhang, Y, Shi, Y, Qi, J, Gao, G.F, Liu, W.J. | | 登録日 | 2018-09-17 | | 公開日 | 2019-09-18 | | 最終更新日 | 2021-03-31 | | 実験手法 | X-RAY DIFFRACTION (2.314 Å) | | 主引用文献 | Salt bridge-forming residues positioned over viral peptides presented by MHC class I impacts T-cell recognition in a binding-dependent manner.
Mol.Immunol., 112, 2019
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6JCY
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3BGW
 | | The Structure Of A DnaB-Like Replicative Helicase And Its Interactions With Primase | | 分子名称: | DNAB-Like Replicative Helicase | | 著者 | Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S. | | 登録日 | 2007-11-27 | | 公開日 | 2007-12-25 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.91 Å) | | 主引用文献 | The structure of a DnaB-family replicative helicase and its interactions with primase.
Nat.Struct.Mol.Biol., 15, 2008
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4IMJ
 | | Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine-tune the Phosphatase Activity of Ssu72 | | 分子名称: | CG14216, CTD, PHOSPHATE ION, ... | | 著者 | Luo, Y, Yogesha, S.D, Zhang, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-08-07 | | 最終更新日 | 2013-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72.
Acs Chem.Biol., 8, 2013
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4HWZ
 | | Structure of HLA-A68 complexed with an HIV derived peptide | | 分子名称: | 9-mer peptide from Pol protein, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | 登録日 | 2012-11-09 | | 公開日 | 2013-10-16 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.397 Å) | | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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3C3I
 | | Evolution of chlorella virus dUTPase | | 分子名称: | DEOXYURIDINE-5'-DIPHOSPHATE, Deoxyuridine triphosphatase, MAGNESIUM ION | | 著者 | Yamanishi, M, Homma, K, Zhang, Y, Etten, L.V.J, Moriyama, H. | | 登録日 | 2008-01-28 | | 公開日 | 2009-02-10 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Crystallization and crystal-packing studies of Chlorella virus deoxyuridine triphosphatase.
Acta Crystallogr.,Sect.F, 65, 2009
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4MQ9
 | | Crystal structure of Thermus thermophilus RNA polymerase holoenzyme in complex with GE23077 | | 分子名称: | (2Z)-2-methylbut-2-enoic acid, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | | 著者 | Ho, M.X, Arnold, E, Ebright, R.H, Zhang, Y, Tuske, S. | | 登録日 | 2013-09-16 | | 公開日 | 2014-05-07 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | GE23077 binds to the RNA polymerase 'i' and 'i+1' sites and prevents the binding of initiating nucleotides.
Elife, 3, 2014
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8JE4
 | | Crystal structure of LimF prenyltransferase (H239G/W273T mutant) bound with the thiodiphosphate moiety of farnesyl S-thiolodiphosphate (FSPP) | | 分子名称: | MAGNESIUM ION, TRIHYDROGEN THIODIPHOSPHATE, prenyltransferase, ... | | 著者 | Hamada, K, Oguni, A, Zhang, Y, Satake, M, Goto, Y, Suga, H, Ogata, K, Sengoku, T. | | 登録日 | 2023-05-15 | | 公開日 | 2023-11-08 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Switching Prenyl Donor Specificities of Cyanobactin Prenyltransferases.
J.Am.Chem.Soc., 145, 2023
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3BH0
 | | ATPase Domain of G40P | | 分子名称: | DNAB-LIKE REPLICATIVE HELICASE | | 著者 | Wang, G, Klein, M.G, Tokonzaba, E, Zhang, Y, Holden, L.G, Chen, X.S. | | 登録日 | 2007-11-27 | | 公開日 | 2007-12-25 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | The structure of a DnaB-family replicative helicase and its interactions with primase.
Nat.Struct.Mol.Biol., 15, 2008
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7CZ5
 | | Cryo-EM structure of the human growth hormone-releasing hormone receptor-Gs protein complex | | 分子名称: | CHOLESTEROL, Growth hormone-releasing hormone receptor,growth hormone-releasing hormone receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | 著者 | Zhou, F, Zhang, H, Cong, Z, Zhao, L, Zhou, Q, Mao, C, Cheng, X, Shen, D, Cai, X, Ma, C, Wang, Y, Dai, A, Zhou, Y, Sun, W, Zhao, F, Zhao, S, Jiang, H, Jiang, Y, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | | 登録日 | 2020-09-07 | | 公開日 | 2020-11-18 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | Structural basis for activation of the growth hormone-releasing hormone receptor.
Nat Commun, 11, 2020
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7D68
 | | Cryo-EM structure of the human glucagon-like peptide-2 receptor-Gs protein complex | | 分子名称: | Glucagon-like peptide 2 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | | 著者 | Sun, W, Chen, L, Zhou, Q, Zhao, L, Zhang, H, Cong, Z, Shen, D, Zhao, F, Zhou, F, Cai, X, Chen, Y, Zhou, Y, Gadgaard, S, van der Velden, W.J, Zhao, S, Jiang, Y, Rosenkilde, M.M, Yang, D, Xu, H.E, Zhang, Y, Wang, M. | | 登録日 | 2020-09-29 | | 公開日 | 2020-12-16 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | A unique hormonal recognition feature of the human glucagon-like peptide-2 receptor.
Cell Res., 30, 2020
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4I48
 | | Structure of HLA-A68 complexed with an HIV Env derived peptide | | 分子名称: | 9-mer peptide from Envelope glycoprotein gp160, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | | 著者 | Niu, L, Cheng, H, Zhang, S, Tan, S, Zhang, Y, Qi, J, Liu, J, Gao, G.F. | | 登録日 | 2012-11-27 | | 公開日 | 2013-10-02 | | 実験手法 | X-RAY DIFFRACTION (2.799 Å) | | 主引用文献 | Structural basis for the differential classification of HLA-A*6802 and HLA-A*6801 into the A2 and A3 supertypes
Mol.Immunol., 55, 2013
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7CT5
 | | S protein of SARS-CoV-2 in complex bound with T-ACE2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | | 著者 | Guo, L, Bi, W.W, Zhang, Y.Y, Yan, R.H, Li, Y.N, Zhou, Q, Dang, B.B. | | 登録日 | 2020-08-18 | | 公開日 | 2020-11-18 | | 最終更新日 | 2021-02-10 | | 実験手法 | ELECTRON MICROSCOPY (4 Å) | | 主引用文献 | Engineered trimeric ACE2 binds viral spike protein and locks it in "Three-up" conformation to potently inhibit SARS-CoV-2 infection.
Cell Res., 31, 2021
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4IMI
 | | Novel Modifications on C-terminal Domain of RNA Polymerase II can Fine- tune the Phosphatase Activity of Ssu72. | | 分子名称: | CG14216, CTD, PHOSPHATE ION, ... | | 著者 | Luo, Y, Yogesha, S.D, Zhang, Y. | | 登録日 | 2013-01-03 | | 公開日 | 2013-08-07 | | 最終更新日 | 2013-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Novel Modifications on C-terminal Domain of RNA Polymerase II Can Fine-tune the Phosphatase Activity of Ssu72.
Acs Chem.Biol., 8, 2013
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4MEX
 | | Crystal structure of Escherichia coli RNA polymerase in complex with salinamide A | | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | | 著者 | Feng, Y, Zhang, Y, Arnold, E, Ebright, R.H. | | 登録日 | 2013-08-27 | | 公開日 | 2014-05-21 | | 最終更新日 | 2014-06-25 | | 実験手法 | X-RAY DIFFRACTION (3.902 Å) | | 主引用文献 | Transcription inhibition by the depsipeptide antibiotic salinamide A.
Elife, 3, 2014
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6O1E
 | | The crystal structure of human MORC3 ATPase-CW in complex with AMPPNP | | 分子名称: | MAGNESIUM ION, MORC family CW-type zinc finger protein 3, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ... | | 著者 | Klein, B.J, Zhang, Y, Kutateladze, T.G. | | 登録日 | 2019-02-19 | | 公開日 | 2019-03-20 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.41 Å) | | 主引用文献 | Mechanism for autoinhibition and activation of the MORC3 ATPase.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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5VRT
 | | Nonheme Iron Replacement in a Biosynthetic Nitric Oxide Reductase Model Performing O2 Reduction to Water: Co-bound FeBMb | | 分子名称: | COBALT (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Reed, J, Shi, Y, Zhu, Q, Chakraborty, S, Mirs, E.N, Petrik, I.D, Bhagi-Damodaran, A, Ross, M, Moenne-Loccoz, P, Zhang, Y, Lu, Y. | | 登録日 | 2017-05-11 | | 公開日 | 2017-08-16 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | | 主引用文献 | Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism.
J. Am. Chem. Soc., 139, 2017
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6JV0
 | | Crystal Structure of N-terminal domain of ArgZ, bound to Product, an arginine dihydrolase from the Ornithine-Ammonia Cycle in Cyanobacteria | | 分子名称: | 1,2-ETHANEDIOL, L-ornithine, Sll1336 protein | | 著者 | Zhuang, N, Li, L, Wu, X, Zhang, Y. | | 登録日 | 2019-04-15 | | 公開日 | 2020-01-15 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.14 Å) | | 主引用文献 | Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
J.Biol.Chem., 295, 2020
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7EPX
 | | S protein of SARS-CoV-2 in complex with GW01 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | | 著者 | Shen, Y.P, Zhang, Y.Y, Yan, R.H, Li, Y.N, Zhou, Q. | | 登録日 | 2021-04-28 | | 公開日 | 2022-05-18 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Novel sarbecovirus bispecific neutralizing antibodies with exceptional breadth and potency against currently circulating SARS-CoV-2 variants and sarbecoviruses.
Cell Discov, 8, 2022
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6JUY
 | | Crystal Structure of ArgZ, apo structure, an Arginine Dihydrolase from the Ornithine-Ammonia Cycle in Cyanobacteria | | 分子名称: | Sll1336 protein | | 著者 | Zhuang, N, Li, L, Wu, X, Zhang, Y. | | 登録日 | 2019-04-15 | | 公開日 | 2020-01-15 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.97 Å) | | 主引用文献 | Crystal structures and biochemical analyses of the bacterial arginine dihydrolase ArgZ suggests a "bond rotation" catalytic mechanism.
J.Biol.Chem., 295, 2020
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3TDB
 | | Human Pin1 bound to trans peptidomimetic inhibitor | | 分子名称: | 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, N-[(1E,2R)-1-[(2R)-2-{[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl}cyclopentylidene]-3-(phosphonooxy)propan-2-yl]-L-phenylalaninamide, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | | 著者 | Zhang, M, Zhang, Y. | | 登録日 | 2011-08-10 | | 公開日 | 2012-06-27 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.267 Å) | | 主引用文献 | Structural and Kinetic Analysis of Prolyl-isomerization/Phosphorylation Cross-Talk in the CTD Code.
Acs Chem.Biol., 7, 2012
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3KPK
 | | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans, C160A mutant | | 分子名称: | DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, HYDROSULFURIC ACID, ... | | 著者 | Cherney, M.M, Zhang, Y, Solomonson, M, Weiner, J.H, James, M.N.G. | | 登録日 | 2009-11-16 | | 公開日 | 2010-04-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Crystal structure of sulfide:quinone oxidoreductase from Acidithiobacillus ferrooxidans: insights into sulfidotrophic respiration and detoxification.
J.Mol.Biol., 398, 2010
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