7DTJ
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3PWR
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![BU of 3pwr by Molmil](/molmil-images/mine/3pwr) | HIV-1 Protease Mutant L76V complexed with Saquinavir | 分子名称: | (2S)-N-[(2S,3R)-4-[(2S,3S,4aS,8aS)-3-(tert-butylcarbamoyl)-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-2-yl]-3-hydroxy-1 -phenyl-butan-2-yl]-2-(quinolin-2-ylcarbonylamino)butanediamide, CHLORIDE ION, GLYCEROL, ... | 著者 | Zhang, Y, Weber, I.T. | 登録日 | 2010-12-08 | 公開日 | 2011-04-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | The L76V Drug Resistance Mutation Decreases the Dimer Stability and Rate of Autoprocessing of HIV-1 Protease by Reducing Internal Hydrophobic Contacts. Biochemistry, 50, 2011
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3TG1
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1RBZ
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![BU of 1rbz by Molmil](/molmil-images/mine/1rbz) | Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid | 分子名称: | N-{4-4-(2,4-DIAMINO-6-OXO-1,6-DIHYDRO-PYRIMIDIN-5-YL)-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXY-ETHYL)-BUT-2-YL-BENZOYL}-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GAMMA-GLUTAMYL-GLUTAMIC ACID, PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | 著者 | Zhang, Y, Desharnais, J, Boger, D.L, Wilson, I.A. | 登録日 | 2003-11-03 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Human GAR Tfase complex structure To be Published
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3TKZ
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![BU of 3tkz by Molmil](/molmil-images/mine/3tkz) | Structure of the SHP-2 N-SH2 domain in a 1:2 complex with RVIpYFVPLNR peptide | 分子名称: | PROTEIN (RVIpYFVPLNR peptide), Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Zhang, Y, Zhang, J, Yuan, C, Hard, R.L, Park, I.H, Li, C, Bell, C.E, Pei, D. | 登録日 | 2011-08-29 | 公開日 | 2011-10-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry, 50, 2011
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3TL0
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![BU of 3tl0 by Molmil](/molmil-images/mine/3tl0) | Structure of SHP2 N-SH2 domain in complex with RLNpYAQLWHR peptide | 分子名称: | RLNpYAQLWHR peptide, SULFATE ION, Tyrosine-protein phosphatase non-receptor type 11 | 著者 | Zhang, Y, Zhang, J, Yuan, C, Hard, R.L, Park, I.H, Li, C, Bell, C.E, Pei, D. | 登録日 | 2011-08-29 | 公開日 | 2011-09-28 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | Simultaneous binding of two peptidyl ligands by a SRC homology 2 domain. Biochemistry, 50, 2011
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2GHQ
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1RBQ
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![BU of 1rbq by Molmil](/molmil-images/mine/1rbq) | Human GAR Tfase complex structure with 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid | 分子名称: | N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID, PHOSPHATE ION, PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | 著者 | Zhang, Y, Desharnais, J, Boger, D.L, Wilson, I.A. | 登録日 | 2003-11-03 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.104 Å) | 主引用文献 | Human GAR Tfase complex structure with polyglutamated
10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid To be Published
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1NCR
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![BU of 1ncr by Molmil](/molmil-images/mine/1ncr) | The structure of Rhinovirus 16 when complexed with pleconaril, an antiviral compound | 分子名称: | 3-{3,5-DIMETHYL-4-[3-(3-METHYL-ISOXAZOL-5-YL)-PROPOXY]-PHENYL}-5-TRIFLUOROMETHYL-[1,2,4]OXADIAZOLE, MYRISTIC ACID, ZINC ION, ... | 著者 | Zhang, Y, Simpson, A.A, Bator, C.M, Chakravarty, S, Pevear, D.C, Skochko, G.A, Tull, T.M, Diana, G, Rossmann, M.G. | 登録日 | 2002-12-05 | 公開日 | 2003-12-16 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural and virological studies of the stages of virus replication that are affected by antirhinovirus compounds J.Virol., 78, 2004
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4HBG
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2GHT
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7W7V
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![BU of 7w7v by Molmil](/molmil-images/mine/7w7v) | 'late' E2P of SERCA2b | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-12-06 | 公開日 | 2022-12-14 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
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7W7U
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![BU of 7w7u by Molmil](/molmil-images/mine/7w7u) | The 'Ca2+-unbound' BeF3- of SERCA2b | 分子名称: | BERYLLIUM TRIFLUORIDE ION, MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-12-06 | 公開日 | 2022-12-14 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
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7W7W
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![BU of 7w7w by Molmil](/molmil-images/mine/7w7w) | E2 Pi of SERCA2b | 分子名称: | MAGNESIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2, TETRAFLUOROALUMINATE ION | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-12-06 | 公開日 | 2022-12-14 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
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7W7T
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![BU of 7w7t by Molmil](/molmil-images/mine/7w7t) | The E1-BeF3- 2Ca2+ of SERCA2b | 分子名称: | BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, MAGNESIUM ION, ... | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | 登録日 | 2021-12-06 | 公開日 | 2022-12-14 | 最終更新日 | 2023-01-11 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Multiple sub-state structures of SERCA2b reveal conformational overlap at transition steps during the catalytic cycle. Cell Rep, 41, 2022
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3LZC
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![BU of 3lzc by Molmil](/molmil-images/mine/3lzc) | Crystal structure of Dph2 from Pyrococcus horikoshii | 分子名称: | Dph2 | 著者 | Zhang, Y, Zhu, X, Torelli, A.T, Lee, M, Dzikovski, B, Koralewski, R.M, Wang, E, Freed, J, Krebs, C, Lin, H, Ealick, S.E. | 登録日 | 2010-03-01 | 公開日 | 2010-06-23 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.261 Å) | 主引用文献 | Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme. Nature, 465, 2010
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7KHK
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7KHJ
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7KHG
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![BU of 7khg by Molmil](/molmil-images/mine/7khg) | Crystal structure of KIT kinase domain with a small molecule inhibitor, PLX3397 | 分子名称: | 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-{[6-(trifluoromethyl)pyridin-3-yl]methyl}pyridin-2-amine, Mast/stem cell growth factor receptor Kit | 著者 | Zhang, Y. | 登録日 | 2020-10-21 | 公開日 | 2021-07-07 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Association of Combination of Conformation-Specific KIT Inhibitors With Clinical Benefit in Patients With Refractory Gastrointestinal Stromal Tumors: A Phase 1b/2a Nonrandomized Clinical Trial. Jama Oncol, 7, 2021
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2NOX
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![BU of 2nox by Molmil](/molmil-images/mine/2nox) | Crystal structure of tryptophan 2,3-dioxygenase from Ralstonia metallidurans | 分子名称: | PROTOPORPHYRIN IX CONTAINING FE, Tryptophan 2,3-dioxygenase | 著者 | Zhang, Y, Kang, S.A, Mukherjee, T, Bale, S, Crane, B.R, Begley, T.P, Ealick, S.E. | 登録日 | 2006-10-26 | 公開日 | 2006-12-19 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Crystal structure and mechanism of tryptophan 2,3-dioxygenase, a heme enzyme involved in tryptophan catabolism and in quinolinate biosynthesis. Biochemistry, 46, 2007
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4G7H
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1RBY
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![BU of 1rby by Molmil](/molmil-images/mine/1rby) | Human GAR Tfase complex structure with 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid and substrate beta-GAR | 分子名称: | GLYCINAMIDE RIBONUCLEOTIDE, N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID, PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | 著者 | Zhang, Y, Desharnais, J, Boger, D.L, Wilson, I.A. | 登録日 | 2003-11-03 | 公開日 | 2005-06-14 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Human GAR Tfase complex structure To be Published
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5V21
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7WF9
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7WF8
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![BU of 7wf8 by Molmil](/molmil-images/mine/7wf8) | Crystal structure of mouse SNX25 RGS domain in space group P212121 | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Zhang, Y, Xu, J, Liu, J. | 登録日 | 2021-12-26 | 公開日 | 2022-10-26 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structural Studies Reveal Unique Non-canonical Regulators of G Protein Signaling Homology (RH) Domains in Sorting Nexins. J.Mol.Biol., 434, 2022
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