1RBQ

Human GAR Tfase complex structure with 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid

Summary for 1RBQ

• Entry DOI: 10.2210/pdb1rbq/pdb
• Related: 1MEJ 1MEO 1NJS 1RBM 1RBY 1RBZ 1RC0 1RC1
• Descriptor: PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE, PHOSPHATE ION, N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID, ... (4 entities in total)
• Functional Keywords: protein-cofactor analogue complex, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 93483.58

Authors

Zhang, Y.,Desharnais, J.,Boger, D.L.,Wilson, I.A. (deposition date: 2003-11-03, release date: 2005-06-14, Last modification date: 2023-08-23)

• Primary citation: Zhang, Y.,Desharnais, J.,Boger, D.L.,Wilson, I.A.; Human GAR Tfase complex structure with polyglutamated 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid; To be Published,

Experimental method

X-RAY DIFFRACTION (2.104 Å)