1RBQ
Human GAR Tfase complex structure with 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE | polymer | 209 | 22678.9 | 4 | UniProt (P22102) Pfam (PF00551) | Homo sapiens (human) | GART; GAR transformylase; 5'-phosphoribosylglycinamide transformylase |
| 2 | E, F, H, I, K... (A, B, C, D) | PHOSPHATE ION | non-polymer | 95.0 | 6 | Chemie (PO4) | |||
| 3 | G, J, L, N (A, B, C, D) | N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID | non-polymer | 549.5 | 4 | Chemie (KEU) | |||
| 4 | O, P, Q, R (A, B, C, D) | water | water | 18.0 | 365 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 203 (UniProt: P22102)
| PDB | External Database | Details |
|---|---|---|
| His 204 | - | expression tag |
| His 205 | - | expression tag |
| His 206 | - | expression tag |
| His 207 | - | expression tag |
| His 208 | - | expression tag |
| His 209 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 90715.8 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2767.8 | |
| All* | Total formula weight | 93483.6 |
