1RBQ

Human GAR Tfase complex structure with 10-(trifluoroacetyl)-5,10-dideazaacyclic-5,6,7,8-tetrahydrofolic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE	polymer	209	22678.9	4	UniProt (P22102) Pfam (PF00551) In PDB	Homo sapiens (human)	GART; GAR transformylase; 5'-phosphoribosylglycinamide transformylase
2	A, B, C, D	PHOSPHATE ION	non-polymer		95.0	6	Chemie (PO4)
3	A, B, C, D	N-{4-[(1R)-4-[(2R,4R,5S)-2,4-DIAMINO-6-OXOHEXAHYDROPYRIMIDIN-5-YL]-1-(2,2,2-TRIFLUORO-1,1-DIHYDROXYETHYL)BUTYL]BENZOYL}-D-GLUTAMIC ACID	non-polymer		549.5	4	Chemie (KEU)
4		water	water		18.0	365	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 203 (UniProt: P22102)

PDB	External Database	Details
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	90715.8
Non-Polymers*	Number of molecules	10
	Total formula weight	2767.8
All*	Total formula weight	93483.6

*Water molecules are not included.