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PDB: 1157 results

5V57
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BU of 5v57 by Molmil
3.0A SYN structure of the multi-domain human smoothened receptor in complex with TC114
Descriptor: (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, FLAVIN MONONUCLEOTIDE, N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamide, ...
Authors:Zhang, X, Zhao, F, Wu, Y, Yang, J, Han, G.W, Zhao, S, Ishchenko, A, Ye, L, Lin, X, Ding, K, Dharmarajan, V, Griffin, P.R, Gati, C, Nelson, G, Hunter, M.S, Hanson, M.A, Cherezov, V, Stevens, R.C, Tan, W, Tao, H, Xu, F.
Deposit date:2017-03-13
Release date:2017-05-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3 Å)
Cite:Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.
Nat Commun, 8, 2017
5V56
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BU of 5v56 by Molmil
2.9A XFEL structure of the multi-domain human smoothened receptor (with E194M mutation) in complex with TC114
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN MONONUCLEOTIDE, N-methyl-N-[1-[4-(2-methylpyrazol-3-yl)phthalazin-1-yl]piperidin-4-yl]-4-nitro-2-(trifluoromethyl)benzamide, ...
Authors:Zhang, X, Zhao, F, Wu, Y, Yang, J, Han, G.W, Zhao, S, Ishchenko, A, Ye, L, Lin, X, Ding, K, Dharmarajan, V, Griffin, P.R, Gati, C, Nelson, G, Hunter, M.S, Hanson, M.A, Cherezov, V, Stevens, R.C, Tan, W, Tao, H, Xu, F.
Deposit date:2017-03-13
Release date:2017-05-24
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Crystal structure of a multi-domain human smoothened receptor in complex with a super stabilizing ligand.
Nat Commun, 8, 2017
4DSB
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BU of 4dsb by Molmil
Complex Structure of Abscisic Acid Receptor PYL3 with (+)-ABA in Spacegroup of I 212121 at 2.70A
Descriptor: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL3
Authors:Zhang, X, Zhang, Q, Chen, Z.
Deposit date:2012-02-18
Release date:2012-06-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Complex Structures of the Abscisic Acid Receptor PYL3/RCAR13 Reveal a Unique Regulatory Mechanism
Structure, 20, 2012
4O67
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BU of 4o67 by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with GAMP
Descriptor: Cyclic GMP-AMP synthase, ZINC ION, cGAMP
Authors:Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.444 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O68
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BU of 4o68 by Molmil
Structure of human cyclic GMP-AMP synthase (cGAS)
Descriptor: Cyclic GMP-AMP synthase, ZINC ION
Authors:Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.436 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O69
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BU of 4o69 by Molmil
Human cyclic GMP-AMP synthase (cGAS) in complex with sulfate ion
Descriptor: Cyclic GMP-AMP synthase, SULFATE ION, ZINC ION
Authors:Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.252 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
4O6A
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BU of 4o6a by Molmil
Mouse cyclic GMP-AMP synthase (cGAS) in complex with DNA
Descriptor: Cyclic GMP-AMP synthase, DNA1, DNA2, ...
Authors:Zhang, X, Chen, Z, Zhang, X.W, Chen, Z.J.
Deposit date:2013-12-20
Release date:2014-02-05
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.859 Å)
Cite:The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop.
Cell Rep, 6, 2014
5VJJ
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BU of 5vjj by Molmil
Crystal structure of the flax-rust effector AvrP
Descriptor: Avirulence protein AvrP123, ZINC ION
Authors:Zhang, X, Ericsson, D.J, Williams, S.J, Kobe, B.
Deposit date:2017-04-19
Release date:2017-08-30
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:Crystal structure of the Melampsora lini effector AvrP reveals insights into a possible nuclear function and recognition by the flax disease resistance protein P.
Mol. Plant Pathol., 19, 2018
3KL1
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BU of 3kl1 by Molmil
Crystal structure of abscisic acid receptor PYL2 at 1.55 A
Descriptor: Putative uncharacterized protein At2g26040
Authors:Zhang, X, Wang, G, Chen, Z.
Deposit date:2009-11-06
Release date:2010-11-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Complex Structures of the Abscisic Acid Receptor PYL3/RCAR13 Reveal a Unique Regulatory Mechanism
Structure, 20, 2012
4DS8
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BU of 4ds8 by Molmil
Complex structure of abscisic acid receptor PYL3-(+)-ABA-HAB1 in the presence of Mn2+
Descriptor: (2Z,4E)-5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxocyclohex-2-en-1-yl]-3-methylpenta-2,4-dienoic acid, Abscisic acid receptor PYL3, GLYCEROL, ...
Authors:Zhang, X, Zhang, Q, Wang, G, Chen, Z.
Deposit date:2012-02-18
Release date:2012-06-06
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Complex Structures of the Abscisic Acid Receptor PYL3/RCAR13 Reveal a Unique Regulatory Mechanism
Structure, 20, 2012
3KLX
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BU of 3klx by Molmil
Crystal structure of native abscisic acid receptor PYL3
Descriptor: F3N23.20 protein, SULFATE ION
Authors:Zhang, X, Wang, G, Chen, Z.
Deposit date:2009-11-09
Release date:2010-11-10
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Complex Structures of the Abscisic Acid Receptor PYL3/RCAR13 Reveal a Unique Regulatory Mechanism
Structure, 20, 2012
6IWI
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BU of 6iwi by Molmil
Crystal structure of PDE5A in complex with a novel inhibitor
Descriptor: MAGNESIUM ION, N-[3-(4,5-diethyl-6-oxo-1,6-dihydropyrimidin-2-yl)-4-propoxyphenyl]-2-(4-methylpiperazin-1-yl)acetamide, ZINC ION, ...
Authors:Zhang, X.L, Xu, Y.C.
Deposit date:2018-12-05
Release date:2019-12-11
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (2.155 Å)
Cite:Pharmacokinetics-Driven Optimization of 4(3 H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension.
J.Med.Chem., 62, 2019
7DYA
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BU of 7dya by Molmil
Crystal structure of TmFtn with calcium ions
Descriptor: CALCIUM ION, FE (III) ION, Ferritin
Authors:Zhang, X, Zhao, G.
Deposit date:2021-01-20
Release date:2021-09-01
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:Protein interface redesign facilitates the transformation of nanocage building blocks to 1D and 2D nanomaterials.
Nat Commun, 12, 2021
8HYR
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BU of 8hyr by Molmil
Crystal structure of human KARS apo
Descriptor: Lysine--tRNA ligase
Authors:Zhang, X, Wang, Y.
Deposit date:2023-01-07
Release date:2024-07-10
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of human KARS apo
To Be Published
6IM6
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BU of 6im6 by Molmil
Crystal structure of PDE4D complexed with a novel inhibitor
Descriptor: 1,2-ETHANEDIOL, 7-ethoxy-6-methoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, MAGNESIUM ION, ...
Authors:Zhang, X.L, Su, H.X, Xu, Y.C.
Deposit date:2018-10-22
Release date:2019-10-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.702 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
5YB2
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BU of 5yb2 by Molmil
Crystal structure of LP-11/N44
Descriptor: Envelope glycoprotein, LP-11
Authors:Zhang, X, Wang, X, He, Y.
Deposit date:2017-09-03
Release date:2018-02-28
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Structural Insights into the Mechanisms of Action of Short-Peptide HIV-1 Fusion Inhibitors Targeting the Gp41 Pocket
Front Cell Infect Microbiol, 8, 2018
169L
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BU of 169l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Zhang, X.-J, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995
3JB7
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BU of 3jb7 by Molmil
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
Descriptor: CPV RNA-dependent RNA polymerase, CYTIDINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H.
Deposit date:2015-08-03
Release date:2015-10-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (4 Å)
Cite:In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
4JDL
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BU of 4jdl by Molmil
Crystal structure of native abscisic acid receptor PYL5 at 2.65 Angstrom
Descriptor: Abscisic acid receptor PYL5, GLYCEROL
Authors:Zhang, X, Zhang, Q, Chen, Z.
Deposit date:2013-02-25
Release date:2013-03-13
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structural Insights into the Abscisic Acid Stereospecificity by the ABA Receptors PYR/PYL/RCAR
Plos One, 8, 2013
5GQH
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BU of 5gqh by Molmil
Cryo-EM structure of PaeCas3-AcrF3 complex
Descriptor: CRISPR-associated nuclease/helicase Cas3 subtype I-F/YPEST, anti-CRISPR protein 3
Authors:Zhang, X, Ma, J, Wang, Y, Wang, J.
Deposit date:2016-08-07
Release date:2016-09-21
Last modified:2024-03-20
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:A CRISPR evolutionary arms race: structural insights into viral anti-CRISPR/Cas responses
Cell Res., 26, 2016
3JB6
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BU of 3jb6 by Molmil
In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus
Descriptor: GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, VP1 CSP, ...
Authors:Zhang, X, Ding, K, Yu, X.K, Chang, W, Sun, J.C, Zhou, Z.H.
Deposit date:2015-08-02
Release date:2015-10-28
Last modified:2024-05-15
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:In situ structures of the segmented genome and RNA polymerase complex inside a dsRNA virus.
Nature, 527, 2015
6IMR
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BU of 6imr by Molmil
Crystal structure of PDE4D complexed with a novel inhibitor
Descriptor: (1S)-1-[3-(1H-indol-3-yl)propyl]-6,7-dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbaldehyde, 1,2-ETHANEDIOL, MAGNESIUM ION, ...
Authors:Zhang, X.L, Su, H.X, Xu, Y.C.
Deposit date:2018-10-23
Release date:2019-10-23
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.503 Å)
Cite:Structure-Aided Identification and Optimization of Tetrahydro-isoquinolines as Novel PDE4 Inhibitors Leading to Discovery of an Effective Antipsoriasis Agent.
J.Med.Chem., 62, 2019
151L
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BU of 151l by Molmil
CONSERVATION OF SOLVENT-BINDING SITES IN 10 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: PHOSPHATE ION, T4 LYSOZYME
Authors:Zhang, X.-J, Matthews, B.W.
Deposit date:1994-01-25
Release date:1994-04-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Conservation of solvent-binding sites in 10 crystal forms of T4 lysozyme.
Protein Sci., 3, 1994
5T2C
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BU of 5t2c by Molmil
CryoEM structure of the human ribosome at 3.6 Angstrom resolution
Descriptor: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
Authors:Zhang, X, Lai, M, Zhou, Z.H.
Deposit date:2016-08-23
Release date:2017-01-25
Last modified:2023-08-16
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Structures and stabilization of kinetoplastid-specific split rRNAs revealed by comparing leishmanial and human ribosomes.
Nat Commun, 7, 2016
168L
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BU of 168l by Molmil
PROTEIN FLEXIBILITY AND ADAPTABILITY SEEN IN 25 CRYSTAL FORMS OF T4 LYSOZYME
Descriptor: T4 LYSOZYME
Authors:Zhang, X.-J, Matthews, B.W.
Deposit date:1995-03-24
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Protein flexibility and adaptability seen in 25 crystal forms of T4 lysozyme.
J.Mol.Biol., 250, 1995

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数据于2024-07-17公开中

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