5XK4
 
 | | Retracted state of S65-phosphorylated ubiquitin | | 分子名称: | Polyubiquitin-B | | 著者 | Dong, X, Gong, Z, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C. | | 登録日 | 2017-05-05 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
5XK5
 | | Relaxed state of S65-phosphorylated ubiquitin | | 分子名称: | Polyubiquitin-B | | 著者 | Xu, D, Zhou, G, Qin, L.Y, Ran, M.L, Zhang, C.L, Liu, K, Liu, Z, Zhang, W.P, Tang, C. | | 登録日 | 2017-05-05 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Ubiquitin S65 phosphorylation engenders a pH-sensitive conformational switch
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
|
|
4Q79
 | | Structure of a HG-derivative CsgG | | 分子名称: | CsgG, MERCURY (II) ION | | 著者 | Huang, Y, Zhang, C.X, Cao, B, Zhao, Y, Kou, Y, Ni, D. | | 登録日 | 2014-04-24 | | 公開日 | 2014-12-17 | | 最終更新日 | 2024-03-20 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Structure of the nonameric bacterial amyloid secretion channel
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
5I3O
 | | Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor | | 分子名称: | BMP-2-inducible protein kinase, N-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1H-indazol-3-yl)cyclopropanecarboxamide, SULFATE ION | | 著者 | Counago, R.M, Sorrell, F.J, Krojer, T, Savitsky, P, Elkins, J.M, Axtman, A, Drewry, D, Wells, C, Zhang, C, Zuercher, W, Willson, T.M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Arruda, P, Gileadi, O, Structural Genomics Consortium (SGC) | | 登録日 | 2016-02-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
To Be Published
|
|
5I3R
 | | Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor | | 分子名称: | BMP-2-inducible protein kinase, N-[6-(3-{[(cyclopropylmethyl)sulfonyl]amino}phenyl)-1H-indazol-3-yl]cyclopropanecarboxamide, PHOSPHATE ION | | 著者 | Counago, R.M, Sorrell, F.J, Krojer, T, Savitsky, P, Elkins, J.M, Axtman, A, Drewry, D, Wells, C, Zhang, C, Zuercher, W, Willson, T.M, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Arruda, P, Gileadi, O, Structural Genomics Consortium (SGC) | | 登録日 | 2016-02-10 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
To Be Published
|
|
1U0B
 | | Crystal structure of cysteinyl-tRNA synthetase binary complex with tRNACys | | 分子名称: | Cysteine--tRNA ligase, ZINC ION, cysteinyl tRNA | | 著者 | Hauenstein, S, Zhang, C.M, Hou, Y.M, Perona, J.J. | | 登録日 | 2004-07-13 | | 公開日 | 2004-11-23 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Shape-selective RNA recognition by cysteinyl-tRNA synthetase
Nat.Struct.Mol.Biol., 11, 2004
|
|
3FCS
 | | Structure of complete ectodomain of integrin aIIBb3 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Zhu, J, Luo, B.-H, Xiao, T, Zhang, C, Nishida, N, Springer, T.A. | | 登録日 | 2008-11-22 | | 公開日 | 2009-01-20 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structure of a complete integrin ectodomain in a physiologic resting state and activation and deactivation by applied forces.
Mol.Cell, 32, 2008
|
|
8IQW
 | |
8IQZ
 | |
7N9A
 | |
3N5B
 | | The complex of PII and PipX from Anabaena | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Asr0485 protein, Nitrogen regulatory protein P-II, ... | | 著者 | Jiang, Y.-L, Zhao, M.-X, Xu, B.-Y, Chen, Y.-X, Zhang, C.-C, Zhou, C.-Z. | | 登録日 | 2010-05-24 | | 公開日 | 2010-09-01 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the cyanobacterial signal transduction protein PII in complex with PipX.
J.Mol.Biol., 402, 2010
|
|
3MA6
 | | Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1 | | 分子名称: | 3-(3-bromobenzyl)-1-tert-butyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine, Calmodulin-domain protein kinase 1 | | 著者 | Wernimont, A.K, Qiu, W, Amani, M, Artz, J.D, Hassani, A.A, Senisterra, G, Vedadi, M, Sibley, L.D, Lourido, S, Shokat, K, Zhang, C, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Hui, R, Lin, Y.H, Structural Genomics Consortium (SGC) | | 登録日 | 2010-03-23 | | 公開日 | 2010-07-21 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structure of kinase domain of TgCDPK1 in presence of 3BrB-PP1
To be Published
|
|
6MXT
 | | Crystal structure of human beta2 adrenergic receptor bound to salmeterol and Nb71 | | 分子名称: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, Endolysin, ... | | 著者 | Masureel, M, Zou, Y, Picard, L.P, van der Westhuizen, E, Mahoney, J.P, Rodrigues, J.P.G.L.M, Mildorf, T.J, Dror, R.O, Shaw, D.E, Bouvier, M, Pardon, E, Steyaert, J, Sunahara, R.K, Weis, W.I, Zhang, C, Kobilka, B.K. | | 登録日 | 2018-10-31 | | 公開日 | 2018-11-14 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.95934224 Å) | | 主引用文献 | Structural insights into binding specificity, efficacy and bias of a beta2AR partial agonist.
Nat. Chem. Biol., 14, 2018
|
|
8IQX
 | |
3FBV
 | | Crystal structure of the oligomer formed by the kinase-ribonuclease domain of Ire1 | | 分子名称: | N~2~-1H-benzimidazol-5-yl-N~4~-(3-cyclopropyl-1H-pyrazol-5-yl)pyrimidine-2,4-diamine, Serine/threonine-protein kinase/endoribonuclease IRE1 | | 著者 | Korennykh, A.V, Egea, P.F, Korostelev, A.A, Finer-Moore, J, Zhang, C, Shokat, K.M, Stroud, R.M, Walter, P. | | 登録日 | 2008-11-19 | | 公開日 | 2008-12-16 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | The unfolded protein response signals through high-order assembly of Ire1.
Nature, 457, 2009
|
|
8J0N
 | | cryo-EM structure of human EMC | | 分子名称: | ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | | 著者 | Li, M, Zhang, C, Wu, J, Lei, M. | | 登録日 | 2023-04-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.47 Å) | | 主引用文献 | Structural insights into human EMC and its interaction with VDAC.
Aging (Albany NY), 16, 2024
|
|
8J0O
 | | cryo-EM structure of human EMC and VDAC | | 分子名称: | ER membrane protein complex subunit 1, ER membrane protein complex subunit 10, ER membrane protein complex subunit 2, ... | | 著者 | Li, M, Zhang, C, Wu, J, Lei, M. | | 登録日 | 2023-04-11 | | 公開日 | 2024-04-03 | | 最終更新日 | 2024-04-17 | | 実験手法 | ELECTRON MICROSCOPY (3.32 Å) | | 主引用文献 | Structural insights into human EMC and its interaction with VDAC.
Aging (Albany NY), 16, 2024
|
|
7DHS
 | | Crystal Structure Analysis of the BRD4 | | 分子名称: | 6-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[(1R)-1-phenylethyl]benzo[cd]indol-2-one, Bromodomain-containing protein 4 | | 著者 | Wu, T, Xiang, Q, Wang, C, Wu, C, Zhang, C, Zhang, M, Liu, Z, Zhang, Y, Xiao, L, Xu, Y. | | 登録日 | 2020-11-17 | | 公開日 | 2021-09-15 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Y06014 is a selective BET inhibitor for the treatment of prostate cancer.
Acta Pharmacol.Sin., 42, 2021
|
|
1ZXF
 | | Solution structure of a self-sacrificing resistance protein, CalC from Micromonospora echinospora | | 分子名称: | CalC | | 著者 | Singh, S, Hager, M.H, Zhang, C, Griffith, B.R, Lee, M.S, Hallenga, K, Markley, J.L, Thorson, J.S, Center for Eukaryotic Structural Genomics (CESG) | | 登録日 | 2005-06-08 | | 公開日 | 2005-12-13 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structural insight into the self-sacrifice mechanism of enediyne resistance.
Acs Chem.Biol., 1, 2006
|
|
2FUC
 | | Human alpha-Phosphomannomutase 1 with Mg2+ cofactor bound | | 分子名称: | MAGNESIUM ION, Phosphomannomutase 1 | | 著者 | Silvaggi, N.R, Zhang, C, Lu, Z, Dunaway-Mariano, D, Allen, K.N. | | 登録日 | 2006-01-26 | | 公開日 | 2006-03-21 | | 最終更新日 | 2017-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The X-ray crystal structures of human alpha-phosphomannomutase 1 reveal the structural basis of congenital disorder of glycosylation type 1a.
J.Biol.Chem., 281, 2006
|
|
7L12
 | | CRYSTAL STRUCTURE OF THE SARS-COV-2(2019-NCOV) MAIN PROTEASE IN COMPLEX WITH COMPOUND 14 | | 分子名称: | (5S)-5-{3-[3-(benzyloxy)-5-chlorophenyl]-2-oxo[2H-[1,3'-bipyridine]]-5-yl}pyrimidine-2,4(3H,5H)-dione, 3C-like proteinase | | 著者 | Deshmukh, M.G, Ippolito, J.A, Zhang, C.H, Jorgensen, W.L, Anderson, K.S. | | 登録日 | 2020-12-14 | | 公開日 | 2021-03-03 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations.
Acs Cent.Sci., 7, 2021
|
|
8IQY
 | |
8IQV
 | |
4IH9
 | | Crystal structure of rice DWARF14 (D14) | | 分子名称: | Dwarf 88 esterase | | 著者 | Zhou, X.E, Zhao, L.-H, Wu, Z.-S, Yi, W, Li, S, Li, Y, Xu, Y, Xu, T.-H, Liu, Y, Chen, R.-Z, Kovach, A, Kang, Y, Hou, L, He, Y, Zhang, C, Melcher, K, Xu, H.E. | | 登録日 | 2012-12-18 | | 公開日 | 2013-01-30 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structures of two phytohormone signal-transducing alpha / beta hydrolases: karrikin-signaling KAI2 and strigolactone-signaling DWARF14.
Cell Res., 23, 2013
|
|
8IR0
 | |
