8KHR
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![BU of 8khr by Molmil](/molmil-images/mine/8khr) | Cryo-EM structure of EBV gH/gL-gp42 in complex with fab 2C1 | Descriptor: | 2C1 heavy chain, 2C1 light chain, Envelope glycoprotein H, ... | Authors: | Fang, X.Y, Zhao, G.X, Zeng, M.S, Liu, Z. | Deposit date: | 2023-08-22 | Release date: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Potent human monoclonal antibodies targeting Epstein-Barr virus gp42 reveal vulnerable sites for virus infection. Cell Rep Med, 5, 2024
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8KFA
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![BU of 8kfa by Molmil](/molmil-images/mine/8kfa) | Cryo-EM structure of HSV-1 gB with D48 Fab complex | Descriptor: | D48 heavy chain, D48 light chain, Envelope glycoprotein B | Authors: | Yang, J, Sun, C, Fang, X, Zeng, M, Liu, Z. | Deposit date: | 2023-08-15 | Release date: | 2024-01-03 | Method: | ELECTRON MICROSCOPY (3.04 Å) | Cite: | The structure of HSV-1 gB bound to a potent neutralizing antibody reveals a conservative antigenic domain across herpesviruses hlife, 2023
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5IZU
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![BU of 5izu by Molmil](/molmil-images/mine/5izu) | |
5IWZ
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![BU of 5iwz by Molmil](/molmil-images/mine/5iwz) | Synaptonemal complex protein | Descriptor: | Synaptonemal complex protein 2 | Authors: | Feng, J, Fu, S, Cao, X, Wu, H, Lu, J, Zeng, M, Liu, L, Yang, X, Shen, Y. | Deposit date: | 2016-03-23 | Release date: | 2017-03-29 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.098 Å) | Cite: | Structure of synaptonemal complexes protein at 2.6 angstroms resolution To Be Published
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7D5Z
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![BU of 7d5z by Molmil](/molmil-images/mine/7d5z) | Crystal structure of EBV gH/gL bound with neutralizing antibody 1D8 | Descriptor: | Envelope glycoprotein H, Envelope glycoprotein L, heavy chain of 1D8, ... | Authors: | Zhu, Q, Shan, S, Yu, J, Wang, X, Zhang, L, Zeng, M. | Deposit date: | 2020-09-28 | Release date: | 2021-10-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (4.2 Å) | Cite: | A Neutralizing Antibody Targeting a New Site of Vulnerability on Epstein-Barr Virus gH/gL Protects against Dual-Tropic Infection To Be Published
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5T35
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![BU of 5t35 by Molmil](/molmil-images/mine/5t35) | The PROTAC MZ1 in complex with the second bromodomain of Brd4 and pVHL:ElonginC:ElonginB | Descriptor: | (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Bromodomain-containing protein 4, Transcription elongation factor B polypeptide 1, ... | Authors: | Gadd, M.S, Zengerle, M, Ciulli, A. | Deposit date: | 2016-08-24 | Release date: | 2017-03-08 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat. Chem. Biol., 13, 2017
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8AQF
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![BU of 8aqf by Molmil](/molmil-images/mine/8aqf) | CRYSTAL STRUCTURE OF HUMAN MONOGLYCERIDE LIPASE WITH COMPOUND LEI-515 | Descriptor: | 1-[(~{R})-[2-chloranyl-4-[(2~{S},3~{S})-4-(3-chlorophenyl)-2,3-dimethyl-piperazin-1-yl]carbonyl-phenyl]sulfinyl]-3,3-bis(fluoranyl)pentan-2-one, Monoglyceride lipase | Authors: | Jiang, M, Huizenga, M, Wirt, J, Paloczi, J, Amedi, A, van der Berg, R, Benz, J, Collin, L, Deng, H, Driever, W, Florea, B, Grether, U, Janssen, A, Heitman, L, Lam, T.W, Mohr, F, Pavlovic, A, Ruf, I, Rutjes, H, Stevens, F, van der Vliet, D, van der Wel, T, Wittwer, M, Boeckel, C, Pacher, P, Hohmann, A, van der Stelt, M. | Deposit date: | 2022-08-12 | Release date: | 2023-08-23 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Discovery of a peripheral restricted, reversible monoacylglycerol lipase inhibitor that reduces liver injury and chemotherapy-induced neuropathy To Be Published
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