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PDB: 81 件
3FBD
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BU of 3fbd by Molmil
Crystal structure of the nuclease domain of COLE7(D493Q mutant) in complex with an 18-BP duplex DNA
分子名称: 5'-D(*DGP*DGP*DAP*DAP*DTP*DTP*DCP*DGP*DAP*DTP*DCP*DGP*DAP*DAP*DTP*DTP*DCP*DC)-3', Colicin-E7
著者Wang, Y.T, Doudeva, L.G, Yuan, H.S.
登録日2008-11-19
公開日2009-11-03
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Redesign of high-affinity nonspecific nucleases with altered sequence preference
To be Published
4P5U
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BU of 4p5u by Molmil
Crystal structure of TatD
分子名称: Tat-linked quality control protein TatD
著者Chen, Y, Li, C.-L, Hsiao, Y.-Y, Duh, Y, Yuan, H.S.
登録日2014-03-20
公開日2014-08-27
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure and function of TatD exonuclease in DNA repair.
Nucleic Acids Res., 42, 2014
3NH0
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BU of 3nh0 by Molmil
Crystal structure of RNase T in complex with a non-preferred ssDNA (AAC)
分子名称: 5'-D(*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2010-06-14
公開日2011-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NGZ
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BU of 3ngz by Molmil
Crystal structure of RNase T in complex with a non-preferred ssDNA (GC) with one Mg in the active site
分子名称: 5'-D(P*GP*C)-3', COBALT (II) ION, MAGNESIUM ION, ...
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2010-06-14
公開日2011-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NH2
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BU of 3nh2 by Molmil
Crystal structure of RNase T in complex with a stem DNA with a 3' overhang
分子名称: 5'-D(P*TP*TP*AP*CP*AP*AP*C)-3', Ribonuclease T
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2010-06-14
公開日2011-02-16
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3NGY
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BU of 3ngy by Molmil
Crystal structure of RNase T (E92G mutant)
分子名称: COBALT (II) ION, Ribonuclease T, his tag sequence
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2010-06-14
公開日2011-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.204 Å)
主引用文献Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
3KRN
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BU of 3krn by Molmil
Crystal Structure of C. elegans cell-death-related nuclease 5(CRN-5)
分子名称: Protein C14A4.5, confirmed by transcript evidence
著者Yang, C.-C, Wang, Y.-T, Hsiao, Y.-Y, Doudeva, L.G, Chow, S.Y, Yuan, H.S.
登録日2009-11-19
公開日2010-01-26
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (3.918 Å)
主引用文献Structural and biochemical characterization of CRN-5 and Rrp46: an exosome component participating in apoptotic DNA degradation
Rna, 16, 2010
2IVK
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BU of 2ivk by Molmil
Crystal structure of the periplasmic endonuclease Vvn complexed with a 16-bp DNA
分子名称: 5'-D(*AP*AP*TP*TP*CP*GP*AP*TP*CP*GP *AP*AP*TP*TP*C)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*T)-3', 5'-D(*GP*AP*AP*TP*TP*CP*GP*AP*TP*CP *GP*AP*AP*TP*TP*C)-3', ...
著者Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S.
登録日2006-06-14
公開日2007-01-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases.
Nucleic Acids Res., 35, 2007
2IVH
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BU of 2ivh by Molmil
Crystal structure of the nuclease domain of ColE7 (H545Q mutant) in complex with an 18-bp duplex DNA
分子名称: 5'-D(*GP*GP*AP*AP*TP*TP*CP*GP*AP*TP *CP*GP*AP*AP*TP*TP*CP*C)-3', COLCIN-E7, ZINC ION
著者Wang, Y.T, Yang, W.J, Li, C.L, Doudeva, L.G, Yuan, H.S.
登録日2006-06-13
公開日2007-01-02
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural Basis for Sequence-Dependent DNA Cleavage by Nonspecific Endonucleases.
Nucleic Acids Res., 35, 2007
3NH1
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BU of 3nh1 by Molmil
Crystal structure of RNase T in complex with a preferred ssDNA (TAGG) with two Mg in the active site
分子名称: 5'-D(*TP*TP*AP*TP*AP*GP*G)-3', MAGNESIUM ION, Ribonuclease T
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2010-06-14
公開日2011-02-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.107 Å)
主引用文献Structural basis for RNA trimming by RNase T in stable RNA 3'-end maturation
Nat.Chem.Biol., 7, 2011
2JAZ
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BU of 2jaz by Molmil
CRYSTAL STRUCTURE OF THE MUTANT N560D OF THE NUCLEASE DOMAIN OF COLE7 IN COMPLEX WITH IM7
分子名称: COLICIN E7, COLICIN E7 IMMUNITY PROTEIN, PHOSPHATE ION, ...
著者Huang, H, Yuan, H.S.
登録日2006-12-01
公開日2007-04-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.03 Å)
主引用文献The Conserved Asparagine in the Hnh Motif Serves an Important Structural Role in Metal Finger Endonucleases.
J.Mol.Biol., 368, 2007
5GKP
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BU of 5gkp by Molmil
Crystal structure of the EndoG worm homologue CPS-6 H148A/F122A in complex with DNA
分子名称: DNA (5'-D(*TP*TP*TP*TP*T)-3'), Endonuclease G, mitochondrial, ...
著者Lin, J.L, Yuan, H.S.
登録日2016-07-05
公開日2016-11-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of endonuclease G in complex with DNA reveals how it nonspecifically degrades DNA as a homodimer.
Nucleic Acids Res., 44, 2016
2JBG
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BU of 2jbg by Molmil
crystal structure of the mutant N560A of the nuclease domain of ColE7 in complex with Im7
分子名称: COLICIN E7, COLICIN-E7 IMMUNITY PROTEIN, SULFATE ION, ...
著者Huang, H, Yuan, H.S.
登録日2006-12-07
公開日2007-04-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The Conserved Asparagine in the Hnh Motif Serves an Important Structural Role in Metal Finger Endonucleases.
J.Mol.Biol., 368, 2007
2JB0
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BU of 2jb0 by Molmil
CRYSTAL STRUCTURE OF THE MUTANT H573A OF THE NUCLEASE DOMAIN OF COLE7 IN COMPLEX WITH IM7
分子名称: COLICIN E7, COLICIN E7 IMMUNITY PROTEIN, ZINC ION
著者Huang, H, Yuan, H.S.
登録日2006-12-01
公開日2007-04-03
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.91 Å)
主引用文献The Conserved Asparagine in the Hnh Motif Serves an Important Structural Role in Metal Finger Endonucleases.
J.Mol.Biol., 368, 2007
5DK5
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BU of 5dk5 by Molmil
Crystal structure of CRN-4-MES complex
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cell death-related nuclease 4, ISOPROPYL ALCOHOL, ...
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2015-09-03
公開日2016-08-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Identification of Inhibitors for the DEDDh Family of Exonucleases and a Unique Inhibition Mechanism by Crystal Structure Analysis of CRN-4 Bound with 2-Morpholin-4-ylethanesulfonate (MES)
J.Med.Chem., 59, 2016
1ZNS
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BU of 1zns by Molmil
Crystal structure of N-ColE7/12-bp DNA/Zn complex
分子名称: 5'-D(*CP*GP*GP*GP*AP*TP*AP*TP*CP*CP*CP*G)-3', Colicin E7, ZINC ION
著者Doudeva, L.G, Huang, H, Hsia, K.C, Shi, Z, Li, C.L, Shen, Y, Yuan, H.S.
登録日2005-05-12
公開日2006-03-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+
Protein Sci., 15, 2006
1ZNV
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BU of 1znv by Molmil
How a His-metal finger endonuclease ColE7 binds and cleaves DNA with a transition metal ion cofactor
分子名称: Colicin E7, Colicin E7 immunity protein, NICKEL (II) ION, ...
著者Doudeva, L.G, Huang, H, Hsia, K.C, Shi, Z, Li, C.L, Shen, Y, Yuan, H.S.
登録日2005-05-12
公開日2006-03-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structural analysis and metal-dependent stability and activity studies of the ColE7 endonuclease domain in complex with DNA/Zn2+ or inhibitor/Ni2+
Protein Sci., 15, 2006
4IUF
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BU of 4iuf by Molmil
Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA
分子名称: 5'-D(*GP*TP*TP*GP*(XUA)P*GP*CP*GP*T)-3', TAR DNA-binding protein 43
著者Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yang, W.Z, Yuan, H.S.
登録日2013-01-21
公開日2014-01-29
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.752 Å)
主引用文献The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.
Nucleic Acids Res., 42, 2014
4KB1
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BU of 4kb1 by Molmil
Crystal structure of RNase T in complex with a bluge DNA (two nucleotide insertion CT )
分子名称: Bulge DNA, MAGNESIUM ION, Ribonuclease T
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2013-04-23
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
4KAZ
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BU of 4kaz by Molmil
Crystal structure of RNase T in complex with a Y structured DNA
分子名称: DNA (5'-D(*TP*TP*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2013-04-23
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
4KB0
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BU of 4kb0 by Molmil
Crystal structure of RNase T in complex with a bluge DNA (Two nucleotide insertion CC )
分子名称: DNA (5'-D(*GP*GP*CP*CP*CP*TP*CP*TP*TP*TP*AP*GP*GP*GP*CP*CP*CP*C)-3'), MAGNESIUM ION, Ribonuclease T
著者Hsiao, Y.-Y, Yuan, H.S.
登録日2013-04-23
公開日2014-03-05
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Structural insights into DNA repair by RNase T--an exonuclease processing 3' end of structured DNA in repair pathways.
Plos Biol., 12, 2014
1ETO
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BU of 1eto by Molmil
THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT R71L
分子名称: FACTOR FOR INVERSION STIMULATION
著者Cheng, Y.S, Yang, W.Z, Johnson, R.C, Yuan, H.S.
登録日2000-04-13
公開日2000-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of the transcriptional activation on Fis: crystal structures of six Fis mutants with different activation properties.
J.Mol.Biol., 302, 2000
1ETQ
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BU of 1etq by Molmil
THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT R71Y
分子名称: FACTOR FOR INVERSION STIMULATION
著者Cheng, Y.S, Yang, W.Z, Johnson, R.C, Yuan, H.S.
登録日2000-04-13
公開日2000-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural analysis of the transcriptional activation on Fis: crystal structures of six Fis mutants with different activation properties.
J.Mol.Biol., 302, 2000
1ETV
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BU of 1etv by Molmil
THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT G72A
分子名称: FACTOR FOR INVERSION STIMULATION
著者Cheng, Y.S, Yang, W.Z, Johnson, R.C, Yuan, H.S.
登録日2000-04-13
公開日2000-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural analysis of the transcriptional activation on Fis: crystal structures of six Fis mutants with different activation properties.
J.Mol.Biol., 302, 2000
1ETK
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BU of 1etk by Molmil
THE CRYSTAL STRUCTURE OF E. COLI FIS MUTANT Q68A
分子名称: FACTOR FOR INVERSION STIMULATION
著者Cheng, Y.S, Yang, W.Z, Johnson, R.C, Yuan, H.S.
登録日2000-04-13
公開日2000-10-11
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural analysis of the transcriptional activation on Fis: crystal structures of six Fis mutants with different activation properties.
J.Mol.Biol., 302, 2000

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