2G3F
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![BU of 2g3f by Molmil](/molmil-images/mine/2g3f) | Crystal Structure of imidazolonepropionase complexed with imidazole-4-acetic acid sodium salt, a substrate homologue | Descriptor: | 2H-IMIDAZOL-4-YLACETIC ACID, Imidazolonepropionase, ZINC ION | Authors: | Yu, Y, Liang, Y.H, Su, X.D. | Deposit date: | 2006-02-19 | Release date: | 2006-09-26 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A catalytic mechanism revealed by the crystal structures of the imidazolonepropionase from Bacillus subtilis J.Biol.Chem., 281, 2006
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4GIF
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![BU of 4gif by Molmil](/molmil-images/mine/4gif) | C-terminal coiled-coil domain of transient receptor potential channel TRPP3 (PKD2L1, Polycystin-L) | Descriptor: | Polycystic kidney disease 2-like 1 protein | Authors: | Yu, Y, Ulbrich, M.H, Li, M.-H, Dobbins, S, Zhang, W.K, Tong, L, Isacoff, E.Y, Yang, J. | Deposit date: | 2012-08-08 | Release date: | 2012-12-05 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Molecular mechanism of the assembly of an acid-sensing receptor ion channel complex. Nat Commun, 3, 2012
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7SDE
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![BU of 7sde by Molmil](/molmil-images/mine/7sde) | Cryo-EM structure of Nse5/6 heterodimer | Descriptor: | Non-structural maintenance of chromosome element 5, Ubiquitin-like protein SMT3,DNA repair protein KRE29 chimera | Authors: | Yu, Y, Patel, D.J, Zhao, X.L. | Deposit date: | 2021-09-29 | Release date: | 2021-10-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | The cryo-EM structure of Nse5/6 complex with the C terminal part of Nse5 To Be Published
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7DOR
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![BU of 7dor by Molmil](/molmil-images/mine/7dor) | E. coli GyrB ATPase domain in complex with 4-nitropheno | Descriptor: | 1H-benzimidazol-2-amine, DNA gyrase subunit B, P-NITROPHENOL, ... | Authors: | Yu, Y, Zhou, H. | Deposit date: | 2020-12-16 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
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7DPR
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![BU of 7dpr by Molmil](/molmil-images/mine/7dpr) | |
7DPS
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![BU of 7dps by Molmil](/molmil-images/mine/7dps) | |
7DQH
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![BU of 7dqh by Molmil](/molmil-images/mine/7dqh) | E. coli GyrB ATPase domain in complex with 2-hydroxybenzamide | Descriptor: | 1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ... | Authors: | Yu, Y, Zhou, H. | Deposit date: | 2020-12-23 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
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7DQI
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![BU of 7dqi by Molmil](/molmil-images/mine/7dqi) | E. coli GyrB ATPase domain in complex with Esculetin | Descriptor: | 1H-benzimidazol-2-amine, 6,7-bis(oxidanyl)chromen-2-one, DNA gyrase subunit B, ... | Authors: | Yu, Y, Zhou, H. | Deposit date: | 2020-12-23 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.91 Å) | Cite: | Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
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7DQJ
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![BU of 7dqj by Molmil](/molmil-images/mine/7dqj) | E. coli GyrB ATPase domain in complex with 3,4-Dihydroxyacetophenone | Descriptor: | 1-[3,4-bis(oxidanyl)phenyl]ethanone, 1H-benzimidazol-2-amine, DNA gyrase subunit B, ... | Authors: | Yu, Y, Zhou, H. | Deposit date: | 2020-12-24 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.92 Å) | Cite: | Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
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7DQF
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7DQU
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![BU of 7dqu by Molmil](/molmil-images/mine/7dqu) | E. coli GyrB ATPase domain in complex with methyl 4-hydroxybenzoate | Descriptor: | 1H-benzimidazol-2-amine, 4-HYDROXY-BENZOIC ACID METHYL ESTER, DNA gyrase subunit B, ... | Authors: | Yu, Y, Zhou, H. | Deposit date: | 2020-12-24 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
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7DQL
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![BU of 7dql by Molmil](/molmil-images/mine/7dql) | E. coli GyrB ATPase domain in complex with 4-chlorobenzene-1,2-diol | Descriptor: | 1H-benzimidazol-2-amine, 4-CHLOROBENZENE-1,2-DIOL, DNA gyrase subunit B, ... | Authors: | Yu, Y, Zhou, H. | Deposit date: | 2020-12-24 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
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7DQM
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![BU of 7dqm by Molmil](/molmil-images/mine/7dqm) | E. coli GyrB ATPase domain in complex with Naringenin | Descriptor: | 1H-benzimidazol-2-amine, DNA gyrase subunit B, PHOSPHATE ION, ... | Authors: | Yu, Y, Zhou, H. | Deposit date: | 2020-12-24 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
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7DQS
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![BU of 7dqs by Molmil](/molmil-images/mine/7dqs) | E. coli GyrB ATPase domain in complex with 2-chlorophenol | Descriptor: | 1H-benzimidazol-2-amine, 2-CHLOROPHENOL, DNA gyrase subunit B, ... | Authors: | Yu, Y, Zhou, H. | Deposit date: | 2020-12-24 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
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7DQW
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![BU of 7dqw by Molmil](/molmil-images/mine/7dqw) | E. coli GyrB ATPase domain in complex with 4-chlorophenol | Descriptor: | 1H-benzimidazol-2-amine, 4-chlorophenol, DNA gyrase subunit B, ... | Authors: | Yu, Y, Zhou, H. | Deposit date: | 2020-12-24 | Release date: | 2021-10-27 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.88 Å) | Cite: | Identification of new building blocks by fragment screening for discovering GyrB inhibitors. Bioorg.Chem., 114, 2021
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5JWA
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![BU of 5jwa by Molmil](/molmil-images/mine/5jwa) | the structure of malaria PfNDH2 | Descriptor: | ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, FRAGMENT OF TRITON X-100, ... | Authors: | Yu, Y, Yang, Y.Q, Li, X.L, Yu, J, Ge, J.P, Li, J, Rao, Y, Yang, M.J. | Deposit date: | 2016-05-11 | Release date: | 2017-03-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.162 Å) | Cite: | Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria J. Med. Chem., 60, 2017
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5JWC
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![BU of 5jwc by Molmil](/molmil-images/mine/5jwc) | Structure of NDH2 from plasmodium falciparum in complex with RYL-552 | Descriptor: | 5-fluoro-3-methyl-2-{4-[4-(trifluoromethoxy)benzyl]phenyl}quinolin-4(1H)-one, FLAVIN-ADENINE DINUCLEOTIDE, FRAGMENT OF TRITON X-100, ... | Authors: | Yu, Y. | Deposit date: | 2016-05-12 | Release date: | 2017-03-22 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.051 Å) | Cite: | Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria J. Med. Chem., 60, 2017
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5JWB
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![BU of 5jwb by Molmil](/molmil-images/mine/5jwb) | Structure of NDH2 from plasmodium falciparum in complex with NADH | Descriptor: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | Authors: | Yu, Y, Li, X.L. | Deposit date: | 2016-05-12 | Release date: | 2017-03-29 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Target Elucidation by Cocrystal Structures of NADH-Ubiquinone Oxidoreductase of Plasmodium falciparum (PfNDH2) with Small Molecule To Eliminate Drug-Resistant Malaria J. Med. Chem., 60, 2017
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1O5T
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![BU of 1o5t by Molmil](/molmil-images/mine/1o5t) | Crystal structure of the aminoacylation catalytic fragment of human tryptophanyl-tRNA synthetase | Descriptor: | Tryptophanyl-tRNA synthetase | Authors: | Yu, Y, Liu, Y, Shen, N, Xu, X, Jia, J, Jin, Y, Arnold, E, Ding, J. | Deposit date: | 2003-10-05 | Release date: | 2004-07-06 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal Structure of Human Tryptophanyl-tRNA Synthetase Catalytic Fragment J.BIOL.CHEM., 279, 2004
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8T64
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![BU of 8t64 by Molmil](/molmil-images/mine/8t64) | Apo Cam1(42-206) | Descriptor: | Cam1 | Authors: | Yu, Y, Patel, D.J. | Deposit date: | 2023-06-15 | Release date: | 2024-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature, 625, 2024
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8T66
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![BU of 8t66 by Molmil](/molmil-images/mine/8t66) | cA6 bound Cam1 | Descriptor: | Cam1, RNA (5'-R(P*AP*AP*AP*AP*A)-3') | Authors: | Yu, Y, Patel, D.J. | Deposit date: | 2023-06-15 | Release date: | 2024-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature, 625, 2024
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8T65
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![BU of 8t65 by Molmil](/molmil-images/mine/8t65) | cA4 bound Cam1 | Descriptor: | Cam1, RNA (5'-R(P*AP*AP*AP*A)-3') | Authors: | Yu, Y, Patel, D.J. | Deposit date: | 2023-06-15 | Release date: | 2024-01-10 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | The CRISPR effector Cam1 mediates membrane depolarization for phage defence. Nature, 625, 2024
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1XTQ
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![BU of 1xtq by Molmil](/molmil-images/mine/1xtq) | Structure of small GTPase human Rheb in complex with GDP | Descriptor: | GTP-binding protein Rheb, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION | Authors: | Yu, Y, Ding, J. | Deposit date: | 2004-10-24 | Release date: | 2005-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structural Basis for the Unique Biological Function of Small GTPase RHEB J.Biol.Chem., 280, 2005
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1XTS
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![BU of 1xts by Molmil](/molmil-images/mine/1xts) | Structure of small GTPase human Rheb in complex with GTP | Descriptor: | GTP-binding protein Rheb, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | Authors: | Yu, Y, Ding, J. | Deposit date: | 2004-10-24 | Release date: | 2005-03-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Basis for the Unique Biological Function of Small GTPase RHEB J.Biol.Chem., 280, 2005
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1XTR
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![BU of 1xtr by Molmil](/molmil-images/mine/1xtr) | |