1EIK
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![BU of 1eik by Molmil](/molmil-images/mine/1eik) | Solution Structure of RNA Polymerase Subunit RPB5 from Methanobacterium Thermoautotrophicum | Descriptor: | RNA POLYMERASE SUBUNIT RPB5 | Authors: | Yee, A, Booth, V, Dharamsi, A, Engel, A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2000-02-25 | Release date: | 2000-06-21 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of the RNA polymerase subunit RPB5 from Methanobacterium thermoautotrophicum. Proc.Natl.Acad.Sci.USA, 97, 2000
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6FFT
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![BU of 6fft by Molmil](/molmil-images/mine/6fft) | Neutron structure of human transthyretin (TTR) S52P mutant in complex with tafamidis at room temperature to 2A resolution (quasi-Laue) | Descriptor: | 2-(3,5-dichlorophenyl)-1,3-benzoxazole-6-carboxylic acid, Transthyretin | Authors: | Yee, A.W, Moulin, M, Blakeley, M.P, Haertlein, M, Mitchell, E.P, Forsyth, V.T. | Deposit date: | 2018-01-09 | Release date: | 2019-01-02 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (2 Å), X-RAY DIFFRACTION | Cite: | A molecular mechanism for transthyretin amyloidogenesis. Nat Commun, 10, 2019
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8ELJ
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![BU of 8elj by Molmil](/molmil-images/mine/8elj) | SARS-CoV-2 spike glycoprotein in complex with the ICO-hu23 neutralizing antibody Fab fragment | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ICO-hu23 antibody Fab heavy chain, ... | Authors: | Yee, A.W, Morizumi, T, Kim, K, Kuo, A, Ernst, O.P. | Deposit date: | 2022-09-24 | Release date: | 2023-07-19 | Last modified: | 2023-08-16 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates. Plos Pathog., 19, 2023
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5NFE
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![BU of 5nfe by Molmil](/molmil-images/mine/5nfe) | Neutron structure of human transthyretin (TTR) T119M mutant at room temperature to 1.85A resolution | Descriptor: | Transthyretin | Authors: | Yee, A.W, Moulin, M, Blakeley, M.P, Ostermann, A, Cooper, J.B, Haertlein, M, Mitchell, E.P, Forsyth, V.T. | Deposit date: | 2017-03-14 | Release date: | 2019-01-02 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (1.853 Å), X-RAY DIFFRACTION | Cite: | A molecular mechanism for transthyretin amyloidogenesis. Nat Commun, 10, 2019
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5NFW
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![BU of 5nfw by Molmil](/molmil-images/mine/5nfw) | Neutron structure of human transthyretin (TTR) S52P mutant at room temperature to 1.8A resolution (quasi-Laue) | Descriptor: | Transthyretin | Authors: | Yee, A.W, Moulin, M, Blakeley, M.P, Cooper, J.B, Haertlein, M, Mitchell, E.P, Forsyth, V.T. | Deposit date: | 2017-03-16 | Release date: | 2019-01-02 | Last modified: | 2024-05-01 | Method: | NEUTRON DIFFRACTION (1.8 Å), X-RAY DIFFRACTION | Cite: | A molecular mechanism for transthyretin amyloidogenesis. Nat Commun, 10, 2019
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5CN3
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![BU of 5cn3 by Molmil](/molmil-images/mine/5cn3) | X-ray structure of wild-type TTR at 1.30A resolution | Descriptor: | Transthyretin | Authors: | Yee, A.W, Moulin, M, Mossou, E, Haertlein, M, Mitchell, E.P, Cooper, J.B, Forsyth, V.T. | Deposit date: | 2015-07-17 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.3 Å) | Cite: | Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses. Angew.Chem.Int.Ed.Engl., 55, 2016
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5CNH
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![BU of 5cnh by Molmil](/molmil-images/mine/5cnh) | X-ray structure of perdeuterated wild-type TTR at 1.42A resolution | Descriptor: | Transthyretin | Authors: | Yee, A.W, Moulin, M, Mossou, E, Haertlein, M, Mitchell, E.P, Cooper, J.B, Forsyth, V.T. | Deposit date: | 2015-07-17 | Release date: | 2016-07-06 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses. Angew.Chem.Int.Ed.Engl., 55, 2016
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5CM1
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![BU of 5cm1 by Molmil](/molmil-images/mine/5cm1) | X-ray structure of perdeuterated TTR mutant - T119M at 1.22A | Descriptor: | Transthyretin | Authors: | Yee, A.W, Moulin, M, Mossou, E, Haertlein, M, Mitchell, E.P, Cooper, J.B, Forsyth, V.T. | Deposit date: | 2015-07-16 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | X-ray structure of perdeuterated TTR mutant - T119M at 1.22A To Be Published
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1RYJ
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![BU of 1ryj by Molmil](/molmil-images/mine/1ryj) | Solution NMR Structure of Protein Mth1743 from Methanobacterium thermoautotrophicum. Ontario Centre for Structural Proteomics target MTH1743_1_70; Northeast Structural Genomics Consortium Target TT526. | Descriptor: | unknown | Authors: | Yee, A, Chang, X, Pineda-Lucena, A, Wu, B, Semesi, A, Le, B, Ramelot, T, Lee, G.M, Bhattacharyya, S, Gutierrez, P, Denisov, A, Lee, C.H, Cort, J.R, Kozlov, G, Liao, J, Finak, G, Chen, L, Wishart, D, Lee, W, McIntosh, L.P, Gehring, K, Kennedy, M.A, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2003-12-22 | Release date: | 2004-02-24 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | AN NMR APPROACH TO STRUCTURAL PROTEOMICS Proc.Natl.Acad.Sci.USA, 99, 2002
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5CLX
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![BU of 5clx by Molmil](/molmil-images/mine/5clx) | X-ray structure of perdeuterated TTR mutant - S52P at 1.28A resolution | Descriptor: | GLYCEROL, Transthyretin | Authors: | Yee, A.W, Moulin, M, Mossou, E, Haertlein, M, Mitchell, E.P, Cooper, J.B, Forsyth, V.T. | Deposit date: | 2015-07-16 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.28 Å) | Cite: | X-ray structure of perdeuterated TTR mutant - S52P at 1.28A resolution To Be Published
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5CLY
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![BU of 5cly by Molmil](/molmil-images/mine/5cly) | X-ray structure of TTR mutant - S52P at 1.23A resolution | Descriptor: | GLYCEROL, Transthyretin | Authors: | Yee, A.W, Moulin, M, Mossou, E, Haertlein, M, Mitchell, E.P, Cooper, J.B, Forsyth, V.T. | Deposit date: | 2015-07-16 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | X-ray structure of TTR mutant - S52P at 1.23A resolution To Be Published
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5CLZ
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![BU of 5clz by Molmil](/molmil-images/mine/5clz) | X-ray structure of TTR mutant - T119M at 1.22A resolution | Descriptor: | Transthyretin | Authors: | Yee, A.W, Moulin, M, Mossou, E, Cooper, J.B, Haertlein, M, Mitchell, E.P, Forsyth, V.T. | Deposit date: | 2015-07-16 | Release date: | 2016-07-27 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.22 Å) | Cite: | X-ray structure of TTR mutant - T119M at 1.22A resolution To Be Published
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1JE3
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![BU of 1je3 by Molmil](/molmil-images/mine/1je3) | Solution Structure of EC005 from Escherichia coli | Descriptor: | HYPOTHETICAL 8.6 KDA PROTEIN IN AMYA-FLIE INTERGENIC REGION | Authors: | Yee, A, Gutierrez, P, Kozlov, G, Denisov, A, Gehring, K, Arrowsmith, C. | Deposit date: | 2001-06-15 | Release date: | 2002-03-06 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | An NMR approach to structural proteomics. Proc.Natl.Acad.Sci.USA, 99, 2002
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2RN7
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![BU of 2rn7 by Molmil](/molmil-images/mine/2rn7) | NMR solution structure of TnpE protein from Shigella flexneri. Northeast Structural Genomics Target SfR125 | Descriptor: | IS629 orfA | Authors: | Ramelot, T.A, Cort, J.R, Semesi, A, Garcia, M, Yee, A.A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2007-12-08 | Release date: | 2008-01-15 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | NMR solution structure of TnpE protein from Shigella flexneri. Northeast
Structural Genomics Target SfR125 To be Published
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1LV3
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![BU of 1lv3 by Molmil](/molmil-images/mine/1lv3) | Solution NMR Structure of Zinc Finger Protein yacG from Escherichia coli. Northeast Structural Genomics Consortium Target ET92. | Descriptor: | HYPOTHETICAL PROTEIN YacG, ZINC ION | Authors: | Ramelot, T.A, Cort, J.R, Yee, A.A, Semesi, A, Edwards, A.M, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2002-05-24 | Release date: | 2002-09-11 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR structure of the Escherichia coli protein YacG: a novel sequence motif in the zinc-finger family of proteins. Proteins, 49, 2002
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2GRG
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![BU of 2grg by Molmil](/molmil-images/mine/2grg) | Solution NMR Structure of Protein YNR034W-A from Saccharomyces cerevisiae. Northeast Structural Genomics Consortium Target YT727; Ontario Center for Structural Proteomics Target yst6499. | Descriptor: | hypothetical protein; Ynr034w-ap | Authors: | Wu, B, Yee, A, Ramelot, T, Lemak, A, Semesi, A, Kennedy, M, Edward, A, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2006-04-24 | Release date: | 2006-05-23 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of hypothetical protein yst6499 from Saccharomyces cerevisiae/ Northeast Structural Genomics Consortium Target YT727/ Ontario Center for Structural Proteomics Target yst6499 To be Published
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2G1E
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![BU of 2g1e by Molmil](/molmil-images/mine/2g1e) | Solution Structure of TA0895 | Descriptor: | hypothetical protein Ta0895 | Authors: | Yeo, I.Y, Hong, E, Jung, J, Lee, W, Yee, A, Arrowsmith, C.H. | Deposit date: | 2006-02-14 | Release date: | 2006-12-26 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of TA0895, a MoaD homologue from Thermoplasma acidophilum Proteins, 65, 2006
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2FQH
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![BU of 2fqh by Molmil](/molmil-images/mine/2fqh) | NMR structure of hypothetical protein TA0938 from Termoplasma acidophilum | Descriptor: | Hypothetical protein TA0938 | Authors: | Monleon, D, Esteve, V, Yee, A, Arrowsmith, C, Celda, B, Ontario Centre for Structural Proteomics (OCSP) | Deposit date: | 2006-01-18 | Release date: | 2007-01-09 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | NMR structure of hypothetical protein TA0938 from Thermoplasma acidophilum. Proteins, 67, 2007
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1YWU
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![BU of 1ywu by Molmil](/molmil-images/mine/1ywu) | Solution NMR structure of Pseudomonas Aeruginosa protein PA4608. Northeast Structural Genomics target PaT7 | Descriptor: | hypothetical protein PA4608 | Authors: | Ramelot, T.A, Yee, A.A, Cort, J.R, Semesi, A, Arrowsmith, C.H, Kennedy, M.A, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2005-02-18 | Release date: | 2005-03-29 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR structure and binding studies confirm that PA4608 from Pseudomonas aeruginosa is a PilZ domain and a c-di-GMP binding protein. Proteins, 66, 2007
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2X8N
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![BU of 2x8n by Molmil](/molmil-images/mine/2x8n) | Solution NMR structure of uncharacterized protein CV0863 from Chromobacterium violaceum. NORTHEAST STRUCTURAL GENOMICS TARGET (NESG) target CvT3. OCSP target CV0863. | Descriptor: | CV0863 | Authors: | Gutmanas, A, Fares, C, Yee, A, Lemak, A, Semesi, A, Arrowsmith, C.H, Ontario Centre for Structural Proteomics (OCSP), Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2010-03-10 | Release date: | 2010-04-28 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Solution NMR Structure of Uncharacterized Protein Cv0863 from Chromobacterium Violaceum To be Published
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2M2J
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![BU of 2m2j by Molmil](/molmil-images/mine/2m2j) | Solution NMR structure of the N-terminal domain of STM1478 from Salmonella typhimurium LT2: Target STR147A of the Northeast Structural Genomics consortium (NESG), and APC101565 of the Midwest Center for Structural Genomics (MCSG). | Descriptor: | Putative periplasmic protein | Authors: | Houliston, S, Yee, A, Lemak, A, Garcia, M, Wu, B, Savchenko, A, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-12-21 | Release date: | 2013-05-08 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Structural and Functional Characterization of DUF1471 Domains of Salmonella Proteins SrfN, YdgH/SssB, and YahO. Plos One, 9, 2014
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2NNZ
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![BU of 2nnz by Molmil](/molmil-images/mine/2nnz) | Solution structure of the hypothetical protein AF2241 from Archaeoglobus fulgidus | Descriptor: | Hypothetical protein | Authors: | Ai, X, Semesib, A, Yee, A, Arrowsmith, C.H, Li, S.S.C, Choy, W.Y, Ontario Centre for Structural Proteomics (OCSP) | Deposit date: | 2006-10-24 | Release date: | 2007-08-28 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Hypothetical protein AF2241 from Archaeoglobus fulgidus adopts a cyclophilin-like fold. J.Biomol.Nmr, 38, 2007
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1HYW
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![BU of 1hyw by Molmil](/molmil-images/mine/1hyw) | SOLUTION STRUCTURE OF BACTERIOPHAGE LAMBDA GPW | Descriptor: | HEAD-TO-TAIL JOINING PROTEIN W | Authors: | Maxwell, K.L, Yee, A.A, Booth, V, Arrowsmith, C.H, Gold, M, Davidson, A.R. | Deposit date: | 2001-01-22 | Release date: | 2001-04-25 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | The solution structure of bacteriophage lambda protein W, a small morphogenetic protein possessing a novel fold. J.Mol.Biol., 308, 2001
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1WPI
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![BU of 1wpi by Molmil](/molmil-images/mine/1wpi) | Solution NMR Structure of Protein YKR049C from Saccharomyces cerevisiae. Ontario Centre for Structural Proteomics target YST0250_1_133; Northeast Structural Genomics Consortium YTYst250 | Descriptor: | Hypothetical 15.6 kDa protein in NAP1-TRK2 intergenic region | Authors: | Jung, J.W, Yee, A, Arrowsmith, C.H, Lee, W, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2004-09-03 | Release date: | 2005-09-13 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structure of YKR049C, a putative redox protein from Saccharomyces cerevisiae J.Biochem.Mol.Biol., 38, 2005
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2M4E
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![BU of 2m4e by Molmil](/molmil-images/mine/2m4e) | Solution NMR structure of VV2_0175 from Vibrio vulnificus, NESG target VnR1 and CSGID target IDP91333 | Descriptor: | Putative uncharacterized protein | Authors: | Wu, B, Yee, A, Houliston, S, Lemak, A, Garcia, M, Savchenko, A, Arrowsmith, C.H, Anderson, W.F, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP), Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2013-02-04 | Release date: | 2013-03-13 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution NMR structure of VV2_0175 from Vibrio vulnificus, NESG target VnR1 and CSGID target IDP91333 To be Published
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