3UIT
 
 | | Overall structure of Patj/Pals1/Mals complex | | Descriptor: | ACETATE ION, InaD-like protein, MAGUK p55 subfamily member 5, ... | | Authors: | Zhang, J, Yang, X, Long, J, Shen, Y. | | Deposit date: | 2011-11-06 | | Release date: | 2012-02-22 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structure of an L27 domain heterotrimer from cell polarity complex Patj/Pals1/Mals2 reveals mutually independent L27 domain assembly mode
J.Biol.Chem., 287, 2012
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7Y7J
 | | SARS-CoV-2 S trimer in complex with 1F Fab | | Descriptor: | 1F VH, 1F VL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | Authors: | Zhao, S, Liu, F, Yang, X, Zhong, G. | | Deposit date: | 2022-06-22 | | Release date: | 2023-02-22 | | Method: | ELECTRON MICROSCOPY (4.8 Å) | | Cite: | A core epitope targeting antibody of SARS-CoV-2.
Protein Cell, 14, 2023
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7Y7K
 | | SARS-CoV-2 RBD in complex with 1F Fab | | Descriptor: | 1F VH, 1F VL, Spike protein S1 | | Authors: | Zhao, S, Liu, F, Yang, X, Zhong, G. | | Deposit date: | 2022-06-22 | | Release date: | 2023-02-22 | | Method: | ELECTRON MICROSCOPY (4.4 Å) | | Cite: | A core epitope targeting antibody of SARS-CoV-2.
Protein Cell, 14, 2023
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5IWZ
 | | Synaptonemal complex protein | | Descriptor: | Synaptonemal complex protein 2 | | Authors: | Feng, J, Fu, S, Cao, X, Wu, H, Lu, J, Zeng, M, Liu, L, Yang, X, Shen, Y. | | Deposit date: | 2016-03-23 | | Release date: | 2017-03-29 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.098 Å) | | Cite: | Structure of synaptonemal complexes protein at 2.6 angstroms resolution
To Be Published
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5IZ8
 | | Protein-protein interaction | | Descriptor: | ACE-ALA-GLY-GLU-ALA-LEU-ALA-ASP-NH2, Adenomatous polyposis coli protein, TRIETHYLENE GLYCOL | | Authors: | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | | Deposit date: | 2016-03-25 | | Release date: | 2017-07-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (3.06 Å) | | Cite: | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
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5IZ6
 | | Protein-protein interaction | | Descriptor: | Adenomatous polyposis coli protein, DI(HYDROXYETHYL)ETHER, PHQ-ALA-GLY-GLU-ALA-LEU-TYR-GLU-NH2, ... | | Authors: | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | | Deposit date: | 2016-03-25 | | Release date: | 2017-07-05 | | Last modified: | 2024-04-17 | | Method: | X-RAY DIFFRACTION (2.15 Å) | | Cite: | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
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5IZA
 | | Protein-protein interaction | | Descriptor: | ACE-GLY-GLY-GLU-ALA-LEU-ALA-TRP-NH2, Adenomatous polyposis coli protein | | Authors: | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | | Deposit date: | 2016-03-25 | | Release date: | 2017-07-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
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5J0A
 | | Crystal structure of PDZ-binding kinase | | Descriptor: | 4'-HYDROXYCINNAMIC ACID, Lymphokine-activated killer T-cell-originated protein kinase, SULFATE ION | | Authors: | Zou, Q.W, Zhou, H, Yang, X. | | Deposit date: | 2016-03-28 | | Release date: | 2016-09-07 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.74 Å) | | Cite: | The crystal structure of an inactive dimer of PDZ-binding kinase
Biochem.Biophys.Res.Commun., 476, 2016
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5Z0V
 | | Structural insight into the Zika virus capsid encapsulating the viral genome | | Descriptor: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | | Deposit date: | 2017-12-21 | | Release date: | 2018-04-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.913 Å) | | Cite: | Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
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5IZ9
 | | Protein-protein interaction | | Descriptor: | ACE-GLY-GLY-GLU-ALA-LEU-ALA-ASP-NH2, Adenomatous polyposis coli protein | | Authors: | Zhao, Y, Jiang, H, Yang, X, Jiang, F, Song, K, Zhang, J. | | Deposit date: | 2016-03-25 | | Release date: | 2017-07-05 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.93 Å) | | Cite: | Peptidomimetic inhibitors of APC-Asef interaction block colorectal cancer migration.
Nat. Chem. Biol., 13, 2017
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5Z0R
 | | Structural insight into the Zika virus capsid encapsulating the viral genome | | Descriptor: | Extracellular solute-binding protein family 1,viral genome protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | | Authors: | Li, T, Zhao, Q, Yang, X, Chen, C, Yang, K, Wu, C, Zhang, T, Duan, Y, Xue, X, Mi, K, Ji, X, Wang, Z, Yang, H. | | Deposit date: | 2017-12-20 | | Release date: | 2018-04-11 | | Last modified: | 2023-11-22 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural insight into the Zika virus capsid encapsulating the viral genome.
Cell Res., 28, 2018
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5T4D
 | | Cryo-EM structure of Polycystic Kidney Disease protein 2 (PKD2), residues 198-703 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, hPKD:198-703, Polycystin-2 | | Authors: | Shen, P.S, Yang, X, DeCaen, P.G, Liu, X, Bulkley, D, Clapham, D.E, Cao, E. | | Deposit date: | 2016-08-29 | | Release date: | 2016-11-02 | | Last modified: | 2020-07-29 | | Method: | ELECTRON MICROSCOPY (3 Å) | | Cite: | The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs.
Cell, 167, 2016
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4Q2J
 | | A novel structure-based mechanism for DNA-binding of SATB1 | | Descriptor: | DNA-binding protein SATB1 | | Authors: | Wang, Z, Long, J, Yang, X, Shen, Y. | | Deposit date: | 2014-04-08 | | Release date: | 2015-03-11 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.603 Å) | | Cite: | Crystal structure of the ubiquitin-like domain-CUT repeat-like tandem of special AT-rich sequence binding protein 1 (SATB1) reveals a coordinating DNA-binding mechanism.
J.Biol.Chem., 289, 2014
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6VOC
 | | icosahedral symmetry reconstruction of brome mosaic virus (RNA 3+4) | | Descriptor: | Capsid protein | | Authors: | Beren, C, Cui, Y.X, Chakravarty, A, Yang, X, Rao, A.L.N, Knobler, C.M, Zhou, Z.H, Gelbart, W.M. | | Deposit date: | 2020-01-30 | | Release date: | 2020-05-20 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (3.1 Å) | | Cite: | Genome organization and interaction with capsid protein in a multipartite RNA virus.
Proc.Natl.Acad.Sci.USA, 117, 2020
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5D2N
 | | Crystal structure of C25-NLV-HLA-A2 complex | | Descriptor: | ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C25 alpha, ... | | Authors: | Mariuzza, R.A, Yang, X. | | Deposit date: | 2015-08-05 | | Release date: | 2015-10-07 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.099 Å) | | Cite: | Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015
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1Y2I
 | | Crystal Structure of MCSG Target APC27401 from Shigella flexneri | | Descriptor: | Hypothetical Protein S0862 | | Authors: | Brunzelle, J.S, Minasov, G, Yang, X, Shuvalova, L, Collart, F.R, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | | Deposit date: | 2004-11-22 | | Release date: | 2005-01-04 | | Last modified: | 2017-10-11 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Crystal Structure of MCSG Target APC27401 from Shigella flexneri
To be Published
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2A4G
 | | Hepatitis C Protease NS3-4A serine protease with Ketoamide Inhibitor SCH225724 Bound | | Descriptor: | ({1-[1-CARBAMOYL-PHENYL-METHYL)-CARBAMOYL]-METHYL}-AMINOOXALYL)-BUTYLCARBAMOYL)-3-METHYL-BUTYLCARBAMOYL)-CYCLOHEXYL-METHYL)-CARBAMIC ACID ISOBUTYL ESTER, NS3 protease/helicase, NS4a peptide, ... | | Authors: | Arasappan, A, Njoroge, F.G, Chan, T.Y, Bennett, F, Bogen, S.L, Chen, K, Gu, H, Hong, L, Jao, E, Liu, Y.T, Lovey, R.G, Parekh, T, Pike, R.E, Pinto, P, Santhanam, B, Venkatraman, S, Vaccaro, H, Wang, H, Yang, X, Zhu, Z, Mckittrick, B, Saksena, A.K, Girijavallabhan, V, Pichardo, J, Butkiewicz, N, Ingram, R, Malcolm, B, Prongay, A.J, Yao, N, Marten, B, Madison, V, Kemp, S, Levy, O, Lim-Wilby, M, Tamura, S, Ganguly, A.K. | | Deposit date: | 2005-06-28 | | Release date: | 2006-07-04 | | Last modified: | 2024-10-09 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Hepatitis C virus NS3-4a serine protease inhibitors. SAR of P2' moiety with improved potency.
Bioorg.Med.Chem.Lett., 15, 2005
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7KDP
 | | HCMV prefusion gB in complex with fusion inhibitor WAY-174865 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein B, ... | | Authors: | Liu, Y, Heim, P.K, Che, Y, Chi, X, Qiu, X, Han, S, Dormitzer, P.R, Yang, X. | | Deposit date: | 2020-10-09 | | Release date: | 2021-03-17 | | Method: | ELECTRON MICROSCOPY (3.6 Å) | | Cite: | Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion.
Sci Adv, 7, 2021
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7KDD
 | | HCMV postfusion gB in complex with SM5-1 Fab | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Envelope glycoprotein B, ... | | Authors: | Liu, Y, Heim, P.K, Che, Y, Chi, X, Qiu, X, Han, S, Dormitzer, P.R, Yang, X. | | Deposit date: | 2020-10-08 | | Release date: | 2021-03-17 | | Method: | ELECTRON MICROSCOPY (3.5 Å) | | Cite: | Prefusion structure of human cytomegalovirus glycoprotein B and structural basis for membrane fusion.
Sci Adv, 7, 2021
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3Q54
 | | Crystal structure of Escherichia coli BamB | | Descriptor: | Outer membrane assembly lipoprotein YfgL | | Authors: | Dong, C, Hou, H, Yang, X. | | Deposit date: | 2010-12-27 | | Release date: | 2012-05-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.004 Å) | | Cite: | Structure of Escherichia coli BamB and its interaction with POTRA domains of BamA.
Acta Crystallogr.,Sect.D, 68, 2012
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3ULF
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3UE6
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3UIU
 | | Crystal structure of Apo-PKR kinase domain | | Descriptor: | Interferon-induced, double-stranded RNA-activated protein kinase | | Authors: | Li, F, Li, S, Yang, X, Shen, Y, Zhang, T. | | Deposit date: | 2011-11-06 | | Release date: | 2012-11-07 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.903 Å) | | Cite: | Crystal structure of Apo-PKR kinase domain
TO BE PUBLISHED
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3Q5M
 | | Crystal structure of Escherichia coli BamD | | Descriptor: | IODIDE ION, UPF0169 lipoprotein yfiO | | Authors: | Dong, C, Hou, H, Yang, X, Dong, Y, Shen, Y. | | Deposit date: | 2010-12-28 | | Release date: | 2011-12-28 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2.604 Å) | | Cite: | Structure of Escherichia coli BamD and its functional implications in outer membrane protein assembly
Acta Crystallogr.,Sect.D, 68, 2012
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6LPI
 | | Crystal Structure of AHAS holo-enzyme | | Descriptor: | Acetolactate synthase isozyme 1 large subunit, Acetolactate synthase isozyme 1 small subunit, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Zhang, Y, Yang, X, Xi, Z, Shen, Y. | | Deposit date: | 2020-01-10 | | Release date: | 2020-11-18 | | Last modified: | 2023-11-29 | | Method: | X-RAY DIFFRACTION (2.849 Å) | | Cite: | Molecular architecture of the acetohydroxyacid synthase holoenzyme.
Biochem.J., 477, 2020
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