7CXM
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![BU of 7cxm by Molmil](/molmil-images/mine/7cxm) | Architecture of a SARS-CoV-2 mini replication and transcription complex | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | Authors: | Yan, L, Zhang, Y, Ge, J, Zheng, L, Gao, Y, Wang, T, Jia, Z, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | Deposit date: | 2020-09-02 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Architecture of a SARS-CoV-2 mini replication and transcription complex. Nat Commun, 11, 2020
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8X7Z
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7D3C
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5ZUV
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![BU of 5zuv by Molmil](/molmil-images/mine/5zuv) | Crystal Structure of the Human Coronavirus 229E HR1 motif in complex with pan-CoVs inhibitor EK1 | Descriptor: | CHLORIDE ION, Spike glycoprotein,Spike glycoprotein,inhibitor EK1 | Authors: | Yan, L, Yang, B, Wilson, I.A. | Deposit date: | 2018-05-08 | Release date: | 2019-04-10 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.21 Å) | Cite: | A pan-coronavirus fusion inhibitor targeting the HR1 domain of human coronavirus spike. Sci Adv, 5, 2019
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5ZVM
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5ZVK
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8X7X
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![BU of 8x7x by Molmil](/molmil-images/mine/8x7x) | Crystal structure of SADS-CoV fusion core | Descriptor: | CHLORIDE ION, HR1, HR2 | Authors: | Yan, L. | Deposit date: | 2023-11-26 | Release date: | 2024-02-21 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Crystal Structures of Fusion Cores from CCoV-HuPn-2018 and SADS-CoV. Viruses, 16, 2024
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7EIZ
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![BU of 7eiz by Molmil](/molmil-images/mine/7eiz) | Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading | Descriptor: | Helicase, MAGNESIUM ION, Non-structural protein 10, ... | Authors: | Yan, L, Yang, Y.X, Li, M.Y, Zhang, Y, Zheng, L.T, Ge, J, Huang, Y.C, Liu, Z.Y, Wang, T, Gao, S, Zhang, R, Huang, Y.Y, Guddat, L.W, Gao, Y, Rao, Z.H, Lou, Z.Y. | Deposit date: | 2021-04-01 | Release date: | 2021-09-22 | Last modified: | 2023-07-26 | Method: | ELECTRON MICROSCOPY | Cite: | Coupling of N7-methyltransferase and 3'-5' exoribonuclease with SARS-CoV-2 polymerase reveals mechanisms for capping and proofreading Cell, 184, 2021
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5CB2
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![BU of 5cb2 by Molmil](/molmil-images/mine/5cb2) | the structure of candida albicans Sey1p in complex with GMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Protein SEY1 | Authors: | Yan, L, Sun, S, Wang, W, Shi, J, Hu, X, Wang, S, Rao, Z, Hu, J, Lou, Z. | Deposit date: | 2015-06-30 | Release date: | 2015-09-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structures of the yeast dynamin-like GTPase Sey1p provide insight into homotypic ER fusion J.Cell Biol., 210, 2015
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5CA9
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5CA8
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8GW1
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![BU of 8gw1 by Molmil](/molmil-images/mine/8gw1) | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analogue inhibitors | Descriptor: | Helicase, MANGANESE (II) ION, Non-structural protein 7, ... | Authors: | Yan, L, Rao, Z, Lou, Z. | Deposit date: | 2022-09-16 | Release date: | 2023-10-25 | Last modified: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.31 Å) | Cite: | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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7YD3
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![BU of 7yd3 by Molmil](/molmil-images/mine/7yd3) | Single-chain variable fragment of app 3D1 antibody | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Yan, L, Yang, G. | Deposit date: | 2022-07-03 | Release date: | 2023-07-05 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.16 Å) | Cite: | Cross-reactive epitopes between HIV and Coronavirus revealed by 3D1 To Be Published
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7YI6
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5YVD
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5GNU
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![BU of 5gnu by Molmil](/molmil-images/mine/5gnu) | the structure of mini-MFN1 apo | Descriptor: | Mitofusin-1 | Authors: | Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Lou, J. | Deposit date: | 2016-07-25 | Release date: | 2016-11-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (4.113 Å) | Cite: | BDLP-like folding of Mitofusin 1 To Be Published
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5GNT
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![BU of 5gnt by Molmil](/molmil-images/mine/5gnt) | BDLP-like folding of Mitofusin 1 | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1 | Authors: | Yan, L, Yu, C, Ming, Z, Rao, Z, Lou, Z, Hu, J. | Deposit date: | 2016-07-24 | Release date: | 2016-11-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.665 Å) | Cite: | the structure of mini-MFN1 in complex with GDP To Be Published
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5GNR
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![BU of 5gnr by Molmil](/molmil-images/mine/5gnr) | the structure of mini-MFN1 K88A in complex with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Mitofusin-1 | Authors: | Yan, L, Yu, C, Ming, Z, Lou, Z, Rao, Z, Hu, J. | Deposit date: | 2016-07-24 | Release date: | 2016-11-23 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | BDLP-like folding of Mitofusin 1 To Be Published
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5GJK
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![BU of 5gjk by Molmil](/molmil-images/mine/5gjk) | Crystal Structure of BAF47 and BAF155 Complex | Descriptor: | GLYCEROL, PHOSPHATE ION, SWI/SNF complex subunit SMARCC1, ... | Authors: | Yan, L, Qian, C. | Deposit date: | 2016-06-30 | Release date: | 2017-06-07 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.052 Å) | Cite: | Structural Insights into BAF47 and BAF155 Complex Formation. J. Mol. Biol., 429, 2017
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7CYQ
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![BU of 7cyq by Molmil](/molmil-images/mine/7cyq) | Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate state in cap synthesis | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ... | Authors: | Yan, L, Ge, J, Zheng, L, Zhang, Y, Gao, Y, Wang, T, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | Deposit date: | 2020-09-04 | Release date: | 2020-12-09 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (2.83 Å) | Cite: | Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis. Cell, 184, 2021
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7CXN
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![BU of 7cxn by Molmil](/molmil-images/mine/7cxn) | Architecture of a SARS-CoV-2 mini replication and transcription complex | Descriptor: | Helicase, Non-structural protein 7, Non-structural protein 8, ... | Authors: | Yan, L, Zhang, Y, Ge, J, Zheng, L, Gao, Y, Wang, T, Jia, Z, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. | Deposit date: | 2020-09-02 | Release date: | 2020-11-04 | Last modified: | 2024-03-27 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Architecture of a SARS-CoV-2 mini replication and transcription complex. Nat Commun, 11, 2020
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5YEW
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![BU of 5yew by Molmil](/molmil-images/mine/5yew) | Structural basis for GTP hydrolysis and conformational change of mitofusin 1 in mediating mitochondrial fusion | Descriptor: | BERYLLIUM TRIFLUORIDE ION, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Yan, L, Qi, Y, Huang, X, Yu, C. | Deposit date: | 2017-09-20 | Release date: | 2018-01-31 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural basis for GTP hydrolysis and conformational change of MFN1 in mediating membrane fusion Nat. Struct. Mol. Biol., 25, 2018
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6JYT
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8JMY
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6JSJ
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