1CAY
 
 | | WILD-TYPE AND E106Q MUTANT CARBONIC ANHYDRASE COMPLEXED WITH ACETATE | | 分子名称: | ACETIC ACID, CARBONIC ANHYDRASE II, ZINC ION | | 著者 | Hakansson, K, Briand, C, Zaitsev, V, Xue, Y, Liljas, A. | | 登録日 | 1993-02-26 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Wild-type and E106Q mutant carbonic anhydrase complexed with acetate.
Acta Crystallogr.,Sect.D, 50, 1994
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1KOQ
 | | NEISSERIA GONORRHOEAE CARBONIC ANHYDRASE | | 分子名称: | CARBONIC ANHYDRASE, ZINC ION | | 著者 | Huang, S, Xue, Y, Chirica, L, Lindskog, S, Jonsson, B.-H. | | 登録日 | 1998-03-22 | | 公開日 | 1998-12-09 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of carbonic anhydrase from Neisseria gonorrhoeae and its complex with the inhibitor acetazolamide.
J.Mol.Biol., 283, 1998
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1CAZ
 | | WILD-TYPE AND E106Q MUTANT CARBONIC ANHYDRASE COMPLEXED WITH ACETATE | | 分子名称: | ACETIC ACID, CARBONIC ANHYDRASE II, ZINC ION | | 著者 | Hakansson, K, Briand, C, Zaitsev, V, Xue, Y, Liljas, A. | | 登録日 | 1993-02-26 | | 公開日 | 1993-10-31 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Wild-type and E106Q mutant carbonic anhydrase complexed with acetate.
Acta Crystallogr.,Sect.D, 50, 1994
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1M61
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1MX9
 | | Crystal Structure of Human Liver Carboxylesterase in complexed with naloxone methiodide, a heroin analogue | | 分子名称: | (5A,17R)-4,5-EPOXY-3,14-DIHYDROXY-17-METHYL-6-OXO-17-(2-PROPENYL)-MORPHINANIUM, 2-acetamido-2-deoxy-beta-D-glucopyranose, liver Carboxylesterase I | | 著者 | Bencharit, S, Morton, C.L, Xue, Y, Potter, P.M, Redinbo, M.R. | | 登録日 | 2002-10-01 | | 公開日 | 2003-04-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structural Basis of Heroin and Cocaine Metabolism by a Promiscuous Human Drug-Processing Enzyme
Nat.Struct.Biol., 10, 2003
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1MZZ
 | | Crystal Structure of Mutant (M182T)of Nitrite Reductase | | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase | | 著者 | Guo, H, Olesen, K, Xue, Y, Shapliegh, J, Sjolin, L. | | 登録日 | 2002-10-10 | | 公開日 | 2004-09-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The High resolution Crystal Structures of Nitrite Reductase and its mutant Met182Thr from Rhodobacter Sphaeroides Reveal a Gating Mechanism for the Electron Transfer to the Type 1 Copper Center
To be Published
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1MX5
 | | Crystal Structure of Human Liver Carboxylesterase in complexed with homatropine, a cocaine analogue | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, HOMOTROPINE, ... | | 著者 | Bencharit, S, Morton, C.L, Xue, Y, Potter, P.M, Redinbo, M.R. | | 登録日 | 2002-10-01 | | 公開日 | 2003-04-08 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural Basis of Heroin and Cocaine Metabolism by a Promiscuous Human Drug-Processing Enzyme
Nat.Struct.Biol., 10, 2003
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1MZY
 | | Crystal Structure of Nitrite Reductase | | 分子名称: | COPPER (II) ION, Copper-containing nitrite reductase, MAGNESIUM ION | | 著者 | Guo, H, Olesen, K, Xue, Y, Shapliegh, J, Sjolin, L. | | 登録日 | 2002-10-10 | | 公開日 | 2004-09-28 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | The High resolution Crystal Structures of Nitrite Reductase and its mutant Met182Thr from Rhodobacter Sphaeroides Reveal a Gating Mechanism for the Electron Transfer to the Type 1 Copper Center
To be Published
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3JUG
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1OPS
 | | ICE-BINDING SURFACE ON A TYPE III ANTIFREEZE PROTEIN FROM OCEAN POUT | | 分子名称: | TYPE III ANTIFREEZE PROTEIN | | 著者 | Yang, D.S.C, Hon, W.-C, Bubanko, S, Xue, Y, Seetharaman, J, Hew, C.L, Sicheri, F. | | 登録日 | 1997-11-17 | | 公開日 | 1998-05-20 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Identification of the ice-binding surface on a type III antifreeze protein with a "flatness function" algorithm.
Biophys.J., 74, 1998
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1Q07
 | | Crystal structure of the Au(I) form of E. coli CueR, a copper efflux regulator | | 分子名称: | GOLD ION, Transcriptional regulator cueR | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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1Q06
 | | Crystal structure of the Ag(I) form of E. coli CueR, a copper efflux regulator | | 分子名称: | SILVER ION, Transcriptional regulator cueR | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.07 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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1Q09
 | | Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator (space group I4122) | | 分子名称: | SULFATE ION, ZINC ION, Zn(II)-responsive regulator of zntA | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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1Q08
 | | Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator, at 1.9 A resolution (space group P212121) | | 分子名称: | MAGNESIUM ION, PHOSPHATE ION, ZINC ION, ... | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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1Q05
 | | Crystal structure of the Cu(I) form of E. coli CueR, a copper efflux regulator | | 分子名称: | COPPER (I) ION, Transcriptional regulator cueR | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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1Q0A
 | | Crystal structure of the Zn(II) form of E. coli ZntR, a zinc-sensing transcriptional regulator (space group C222) | | 分子名称: | SULFATE ION, ZINC ION, Zn(II)-responsive regulator of zntA | | 著者 | Changela, A, Chen, K, Xue, Y, Holschen, J, Outten, C.E, O'Halloran, T.V, Mondragon, A. | | 登録日 | 2003-07-15 | | 公開日 | 2003-09-16 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Molecular basis of metal-ion selectivity and zeptomolar sensitivity by CueR
Science, 301, 2003
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1SKX
 | | Structural Disorder in the Complex of Human PXR and the Macrolide Antibiotic Rifampicin | | 分子名称: | Orphan nuclear receptor PXR, RIFAMPICIN | | 著者 | Chrencik, J.E, Xue, Y, Orans, J.O, Redinbo, M.R. | | 登録日 | 2004-03-05 | | 公開日 | 2005-03-08 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural disorder in the complex of human pregnane x receptor and the macrolide antibiotic rifampicin
Mol.Endocrinol., 19, 2005
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2YOP
 | | Long wavelength S-SAD structure of FAM3B PANDER | | 分子名称: | GLYCEROL, PROTEIN FAM3B | | 著者 | Johansson, P, Bernstrom, J, Gorman, T, Oster, L, Backstrom, S, Schweikart, F, Xu, B, Xue, Y, Holmberg Schiavone, L. | | 登録日 | 2012-10-26 | | 公開日 | 2013-01-30 | | 最終更新日 | 2013-02-20 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Fam3B Pander and Fam3C Ilei Represent a Distinct Class of Signaling Molecules with a Non-Cytokine-Like Fold.
Structure, 21, 2013
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2YOQ
 | | Structure of FAM3B PANDER E30 construct | | 分子名称: | GLYCEROL, PROTEIN FAM3B | | 著者 | Johansson, P, Bernstrom, J, Gorman, T, Oster, L, Backstrom, S, Schweikart, F, Xu, B, Xue, Y, Holmberg Schiavone, L. | | 登録日 | 2012-10-26 | | 公開日 | 2013-01-30 | | 最終更新日 | 2013-02-20 | | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | | 主引用文献 | Fam3B Pander and Fam3C Ilei Represent a Distinct Class of Signaling Molecules with a Non-Cytokine-Like Fold.
Structure, 21, 2013
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3VMW
 | | Crystal structure of pectate lyase Bsp165PelA from Bacillus sp. N165 in complex with trigalacturonate | | 分子名称: | Pectate lyase, SULFATE ION, alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid-(1-4)-alpha-D-galactopyranuronic acid | | 著者 | Zheng, Y, Huang, C.H, Liu, W, Ko, T.P, Xue, Y, Zhou, C, Zhang, G, Guo, R.T, Ma, Y. | | 登録日 | 2011-12-17 | | 公開日 | 2012-07-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5.
Biochem.Biophys.Res.Commun., 420, 2012
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3VMV
 | | Crystal structure of pectate lyase Bsp165PelA from Bacillus sp. N165 | | 分子名称: | Pectate lyase, SULFATE ION | | 著者 | Zheng, Y, Huang, C.H, Liu, W, Ko, T.P, Xue, Y, Zhou, C, Zhang, G, Guo, R.T, Ma, Y. | | 登録日 | 2011-12-16 | | 公開日 | 2012-07-25 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | | 主引用文献 | Crystal structure and substrate-binding mode of a novel pectate lyase from alkaliphilic Bacillus sp. N16-5.
Biochem.Biophys.Res.Commun., 420, 2012
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4ACM
 | | CDK2 IN COMPLEX WITH 3-AMINO-6-(4-{[2-(DIMETHYLAMINO)ETHYL]SULFAMOYL}-PHENYL)-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE | | 分子名称: | 3-AMINO-6-(4-{[2-(DIMETHYLAMINO)ETHYL]SULFAMOYL}PHENYL)-N-PYRIDIN-3-YLPYRAZINE-2-CARBOXAMIDE, CYCLIN-DEPENDENT KINASE 2, GLYCEROL | | 著者 | Berg, S, Bhat, R, Anderson, M, Bergh, M, Brassington, C, Hellberg, S, Jerning, E, Hogdin, K, Lo-Alfredsson, Y, Neelissen, J, Nilsson, Y, Ormo, M, Soderman, P, Stanway, J, Tucker, J, von Berg, S, Weigelt, T, Xue, Y. | | 登録日 | 2011-12-16 | | 公開日 | 2012-05-16 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Discovery of novel potent and highly selective glycogen synthase kinase-3 beta (GSK3 beta ) inhibitors for Alzheimer's disease: design, synthesis, and characterization of pyrazines.
J. Med. Chem., 55, 2012
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5H7O
 | | Crystal structure of DJ-101 in complex with tubulin protein | | 分子名称: | 2-(1H-indol-4-yl)-4-(3,4,5-trimethoxyphenyl)-1H-imidazo[4,5-c]pyridine, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CALCIUM ION, ... | | 著者 | Arnst, K, Wang, Y, Hwang, D.-J, Xue, Y, Costello, T, Hamilton, D, Chen, Q, Yang, J, Park, F, Dalton, J.T, Miller, D.D, Li, W. | | 登録日 | 2016-11-20 | | 公開日 | 2017-12-13 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | A Potent, Metabolically Stable Tubulin Inhibitor Targets the Colchicine Binding Site and Overcomes Taxane Resistance.
Cancer Res., 78, 2018
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7Q3V
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4AU8
 | | Crystal structure of compound 4a in complex with cdk5, showing an unusual binding mode to the hinge region via a water molecule | | 分子名称: | 4-(1,3-benzothiazol-2-yl)thiophene-2-sulfonamide, CYCLIN-DEPENDENT KINASE 5, IMIDAZOLE, ... | | 著者 | Malmstrom, J, Viklund, J, Slivo, C, Costa, A, Maudet, M, Sandelin, C, Hiller, G, Olsson, L.L, Aagaard, A, Geschwindner, S, Xue, Y, Vasange, M. | | 登録日 | 2012-05-14 | | 公開日 | 2013-03-27 | | 最終更新日 | 2024-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Synthesis and Structure-Activity Relationship of 4-(1,3-Benzothiazol-2-Yl)-Thiophene-2-Sulfonamides as Cyclin-Dependent Kinase 5 (Cdk5)/P25 Inhibitors.
Bioorg.Med.Chem.Lett., 22, 2012
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