1MX5
Crystal Structure of Human Liver Carboxylesterase in complexed with homatropine, a cocaine analogue
Summary for 1MX5
Entry DOI | 10.2210/pdb1mx5/pdb |
Related | 1MX1 1MX9 |
Descriptor | liver Carboxylesterase I, 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, ... (6 entities in total) |
Functional Keywords | esterase, hydrolase, cocaine |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 6 |
Total formula weight | 368919.26 |
Authors | Bencharit, S.,Morton, C.L.,Xue, Y.,Potter, P.M.,Redinbo, M.R. (deposition date: 2002-10-01, release date: 2003-04-08, Last modification date: 2020-07-29) |
Primary citation | Bencharit, S.,Morton, C.L.,Xue, Y.,Potter, P.M.,Redinbo, M.R. Structural Basis of Heroin and Cocaine Metabolism by a Promiscuous Human Drug-Processing Enzyme Nat.Struct.Biol., 10:349-356, 2003 Cited by PubMed: 12679808DOI: 10.1038/nsb919 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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