6JBY
 
 | | Crystal structure of endo-deglycosylated hydroxynitrile lyase isozyme 5 of Prunus communis | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Zheng, Y.C, Li, F.L, Yu, H.L, Xu, J.H. | | 登録日 | 2019-01-27 | | 公開日 | 2020-04-01 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure-Guided Tuning of a Hydroxynitrile Lyase to Accept Rigid Pharmaco Aldehydes.
Acs Catalysis, 2020
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5ZFM
 | | Ketoreductase LbCR mutant - M6 | | 分子名称: | 3-oxoacyl-acyl carrier protein reductase | | 著者 | Gong, X.M, Zheng, G.W, Xu, J.H. | | 登録日 | 2018-03-06 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor
Acs Catalysis, 9, 2019
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5ZI0
 | | Ketoreductase LbCR mutant - M8 | | 分子名称: | 3-oxoacyl-acyl carrier protein reductase | | 著者 | Gong, X.M, Zheng, G.W, Xu, J.H. | | 登録日 | 2018-03-14 | | 公開日 | 2019-01-16 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.302 Å) | | 主引用文献 | Development of an Engineered Ketoreductase with Simultaneously Improved Thermostability and Activity for Making a Bulky Atorvastatin Precursor
Acs Catalysis, 9, 2019
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5YWL
 | | SsCR_L211H | | 分子名称: | Protein induced by osmotic stress | | 著者 | Shang, Y.P, Chen, Q, Li, A.T, Yu, H.L, Xu, J.H. | | 登録日 | 2017-11-29 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.098 Å) | | 主引用文献 | Attenuated substrate inhibition of a haloketone reductase via structure-guided loop engineering.
J.Biotechnol., 308, 2020
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5YWN
 | | SsCR_L211H-NADP+ | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Protein induced by osmotic stress | | 著者 | Shang, Y.P, Chen, Q, Yu, H.L, Xu, J.H. | | 登録日 | 2017-11-29 | | 公開日 | 2019-03-06 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (2.039 Å) | | 主引用文献 | Attenuated substrate inhibition of a haloketone reductase via structure-guided loop engineering.
J.Biotechnol., 308, 2020
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5YW4
 | | Structure-Guided Engineering of Reductase: Efficient Attenuating Substrate Inhibition in Asymmetric Catalysis | | 分子名称: | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Protein induced by osmotic stress | | 著者 | Shang, Y.P, Chen, Q, Li, A.T, Yu, H.L, Xu, J.H. | | 登録日 | 2017-11-28 | | 公開日 | 2019-03-06 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.047 Å) | | 主引用文献 | Attenuated substrate inhibition of a haloketone reductase via structure-guided loop engineering.
J.Biotechnol., 308, 2020
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7XDU
 | | TtherAmDH-NAD+ | | 分子名称: | 4-hydroxy-tetrahydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Chen, C, Qian, Y.Y, Pan, J, Bai, Y.P, Xu, J.H. | | 登録日 | 2022-03-28 | | 公開日 | 2023-04-05 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Stereoselective synthesis of chiral lactams via an engineered natural amine dehydrogenase.
To Be Published
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7XWU
 | | Ketoreductase CpKR mutant - M1 | | 分子名称: | DI(HYDROXYETHYL)ETHER, Epimerase domain-containing protein, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Chen, C, Zheng, Y.C, Pan, J, Xu, J.H. | | 登録日 | 2022-05-27 | | 公開日 | 2023-05-31 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Computational Redesign of a robust Ketoreductase for Asymmetric Synthesis of Enantiopure diltiazem precursor.
To Be Published
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7Y0K
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7CG2
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7CG6
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7DUS
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5YQT
 | | Crystal Structure of the L74F/M78V/I80V/L114F mutant of LEH complexed with cyclopentene oxide | | 分子名称: | (1R,5S)-6-oxabicyclo[3.1.0]hexane, Limonene-1,2-epoxide hydrolase | | 著者 | Kong, X.D, Sun, Z.T, Wu, L, Reetz, M.T, Zhou, J.H, Xu, J.H. | | 登録日 | 2017-11-07 | | 公開日 | 2018-06-27 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations.
J. Am. Chem. Soc., 140, 2018
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