5YQT

Crystal Structure of the L74F/M78V/I80V/L114F mutant of LEH complexed with cyclopentene oxide

Summary for 5YQT

Entry DOI	10.2210/pdb5yqt/pdb
Descriptor	Limonene-1,2-epoxide hydrolase, (1R,5S)-6-oxabicyclo[3.1.0]hexane (3 entities in total)
Functional Keywords	epoxide hydrolase, hydrolase
Biological source	Rhodococcus erythropolis (Arthrobacter picolinophilus)
Total number of polymer chains	8
Total formula weight	139375.63
Authors	Kong, X.D.,Sun, Z.T.,Wu, L.,Reetz, M.T.,Zhou, J.H.,Xu, J.H. (deposition date: 2017-11-07, release date: 2018-06-27, Last modification date: 2023-11-22)
Primary citation	Sun, Z.,Wu, L.,Bocola, M.,Chan, H.C.S.,Lonsdale, R.,Kong, X.D.,Yuan, S.,Zhou, J.,Reetz, M.T. Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations. J. Am. Chem. Soc., 140:310-318, 2018 Cited by PubMed: 29232125 DOI: 10.1021/jacs.7b10278 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation