8D4R
 
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8D01
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8H67
 | | type I-B Cascade bound to a PAM-containing dsDNA target at 3.8 angstrom resolution. | | Descriptor: | CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ... | | Authors: | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | | Deposit date: | 2022-10-15 | | Release date: | 2024-05-01 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure and genome editing of type I-B CRISPR-Cas.
Nat Commun, 15, 2024
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2AMN
 | | Solution structure of Fowlicidin-1, a novel Cathelicidin antimicrobial peptide from chicken | | Descriptor: | cathelicidin | | Authors: | Xiao, Y, Dai, H, Bommineni, Y.R, Prakash, O, Zhang, G. | | Deposit date: | 2005-08-09 | | Release date: | 2006-07-18 | | Last modified: | 2024-05-08 | | Method: | SOLUTION NMR | | Cite: | Structure-activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken.
Febs J., 273, 2006
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6A5A
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6A5E
 | | Crystal structure of plant peptide RALF23 in complex with FER and LLG2 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GPI-anchored protein LLG2, ... | | Authors: | Xiao, Y, Chai, J. | | Deposit date: | 2018-06-23 | | Release date: | 2019-06-26 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.766 Å) | | Cite: | Mechanisms of RALF peptide perception by a heterotypic receptor complex.
Nature, 572, 2019
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6A5B
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2MXU
 | | 42-Residue Beta Amyloid Fibril | | Descriptor: | Amyloid beta A4 protein | | Authors: | Xiao, Y, Ma, B, McElheny, D, Parthasarathy, S, Long, F, Hoshi, M, Nussinov, R, Ishii, Y. | | Deposit date: | 2015-01-14 | | Release date: | 2015-05-06 | | Last modified: | 2024-05-01 | | Method: | SOLID-STATE NMR | | Cite: | A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease.
Nat.Struct.Mol.Biol., 22, 2015
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6A5C
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6A5D
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5Y66
 | | Crystal structure of Pseudomonas fluorescens Kynurenine 3-monooxygenase in complex with L-KYN and Ro61-8048 | | Descriptor: | (2S)-2-amino-4-(2-aminophenyl)-4-oxobutanoic acid, 3,4-dimethoxy-N-[4-(3-nitrophenyl)-1,3-thiazol-2-yl]benzenesulfonamide, FLAVIN-ADENINE DINUCLEOTIDE, ... | | Authors: | Xiang, Y, Gao, J.J, Zhu, D.Y. | | Deposit date: | 2017-08-10 | | Release date: | 2017-12-27 | | Last modified: | 2024-03-27 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Biochemistry and structural studies of kynurenine 3-monooxygenase reveal allosteric inhibition by Ro 61-8048
FASEB J., 32, 2018
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5Y7A
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5Y77
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5XVN
 | | E. far Cas1-Cas2/prespacer binary complex | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | | Authors: | Xiao, Y, Ng, S, Nam, K.H, Ke, A. | | Deposit date: | 2017-06-28 | | Release date: | 2017-10-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3.25 Å) | | Cite: | How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
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5XVO
 | | E. fae Cas1-Cas2/prespacer/target ternary complex revealing DNA sampling and half-integration states | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (28-MER), ... | | Authors: | Xiao, Y, Ng, S, Nam, K.H, Ke, A. | | Deposit date: | 2017-06-28 | | Release date: | 2017-10-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
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5XVP
 | | E. fae Cas1-Cas2/prespacer/target ternary complex revealing the fully integrated states | | Descriptor: | CRISPR-associated endonuclease Cas1, CRISPR-associated endoribonuclease Cas2, DNA (5'-D(P*TP*TP*CP*TP*CP*CP*GP*AP*G)-3'), ... | | Authors: | Xiao, Y, Ng, S, Nam, K.H, Ke, A. | | Deposit date: | 2017-06-28 | | Release date: | 2017-10-04 | | Last modified: | 2024-05-22 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | How type II CRISPR-Cas establish immunity through Cas1-Cas2-mediated spacer integration.
Nature, 550, 2017
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5U0A
 | | CRISPR RNA-guided surveillance complex | | Descriptor: | CRISPR-associated protein, Cas5e family, Cse1 family, ... | | Authors: | Xiao, Y, Luo, M, Hayes, R.P, Kim, J, Ng, S, Ding, F, Liao, M, Ke, A. | | Deposit date: | 2016-11-23 | | Release date: | 2017-08-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
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5U07
 | | CRISPR RNA-guided surveillance complex | | Descriptor: | CRISPR-associated protein, Cas5e family, Cse1 family, ... | | Authors: | Xiao, Y, Luo, M, Hayes, R.P, Kim, J, Ng, S, Ding, F, Liao, M, Ke, A. | | Deposit date: | 2016-11-23 | | Release date: | 2017-08-09 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure Basis for Directional R-loop Formation and Substrate Handover Mechanisms in Type I CRISPR-Cas System.
Cell, 170, 2017
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8J1V
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8J1T
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6C66
 | | CRISPR RNA-guided surveillance complex, pre-nicking | | Descriptor: | CRISPR-associated helicase, Cas3 family, CRISPR-associated protein, ... | | Authors: | Xiao, Y, Luo, M, Liao, M, Ke, A. | | Deposit date: | 2018-01-17 | | Release date: | 2018-06-27 | | Last modified: | 2023-11-29 | | Method: | ELECTRON MICROSCOPY (3.66 Å) | | Cite: | Structure basis for RNA-guided DNA degradation by Cascade and Cas3.
Science, 361, 2018
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3UB0
 | | Crystal structure of the nonstructural protein 7 and 8 complex of Feline Coronavirus | | Descriptor: | Non-structural protein 6, nsp6,, Non-structural protein 7, ... | | Authors: | Xiao, Y, Hilgenfeld, R, Ma, Q. | | Deposit date: | 2011-10-22 | | Release date: | 2012-02-22 | | Last modified: | 2017-11-08 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Nonstructural proteins 7 and 8 of feline coronavirus form a 2:1 heterotrimer that exhibits primer-independent RNA polymerase activity.
J.Virol., 86, 2012
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3OY2
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3SUC
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3OY7
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