7JUA
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7JTJ
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8GV3
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![BU of 8gv3 by Molmil](/molmil-images/mine/8gv3) | The cryo-EM structure of GSNOR with NYY001 | Descriptor: | (4P)-4-{2-[4-(1H-imidazol-1-yl)phenyl]-5-[3-oxo-3-(2-oxo-1,3-thiazolidin-3-yl)propyl]-1H-pyrrol-1-yl}-3-methylbenzamide, Alcohol dehydrogenase class-3, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | Authors: | Xia, Y, Zhang, Q, Yao, D, Zhao, S, Xie, L, Ji, Y, Cao, Y. | Deposit date: | 2022-09-14 | Release date: | 2023-09-20 | Method: | ELECTRON MICROSCOPY (3.05 Å) | Cite: | The cryo-EM structure of GSNOR with NYY001 To Be Published
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1LKN
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7F3N
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![BU of 7f3n by Molmil](/molmil-images/mine/7f3n) | Structure of PopP2 in apo form | Descriptor: | Type III effector protein popp2 | Authors: | Xia, Y, Zhang, Z.M. | Deposit date: | 2021-06-16 | Release date: | 2021-11-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.351856 Å) | Cite: | Secondary-structure switch regulates the substrate binding of a YopJ family acetyltransferase. Nat Commun, 12, 2021
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7F32
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7YFK
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![BU of 7yfk by Molmil](/molmil-images/mine/7yfk) | The structure of human pregnane X receptor in complex with an SRC-1 coactivator peptide and a limonoid compound, nomilin | Descriptor: | Nomilin, Nuclear receptor subfamily 1 group I member 2,Nuclear receptor coactivator 1 | Authors: | Xia, Y, Yao, D, Huang, C, Cao, Y. | Deposit date: | 2022-07-08 | Release date: | 2023-06-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Pregnane X receptor agonist nomilin extends lifespan and healthspan in preclinical models through detoxification functions. Nat Commun, 14, 2023
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3CSQ
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3CT0
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7JVB
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![BU of 7jvb by Molmil](/molmil-images/mine/7jvb) | Crystal structure of the SARS-CoV-2 spike receptor-binding domain (RBD) with nanobody Nb20 | Descriptor: | CACODYLATE ION, Nanobody Nb20, Spike protein S1 | Authors: | Xiang, Y, Xiao, Z, Liu, H, Sang, Z, Schneidman-Duhovny, D, Zhang, C, Shi, Y. | Deposit date: | 2020-08-20 | Release date: | 2020-12-02 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.287 Å) | Cite: | Versatile and multivalent nanobodies efficiently neutralize SARS-CoV-2. Science, 370, 2020
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1P9G
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![BU of 1p9g by Molmil](/molmil-images/mine/1p9g) | Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Ecommia ulmoides Oliver at atomic resolution | Descriptor: | ACETATE ION, EAFP 2 | Authors: | Xiang, Y, Huang, R.H, Liu, X.Z, Wang, D.C. | Deposit date: | 2003-05-12 | Release date: | 2004-06-01 | Last modified: | 2019-12-25 | Method: | X-RAY DIFFRACTION (0.84 Å) | Cite: | Crystal structure of a novel antifungal protein distinct with five disulfide bridges from Eucommia ulmoides Oliver at an atomic resolution. J.Struct.Biol., 148, 2004
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6A5B
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8TGO
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![BU of 8tgo by Molmil](/molmil-images/mine/8tgo) | Crystal structure of the BG505 triple tandem trimer gp140 HIV-1 Env in complex with PGT124 and 35O22 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35O22 scFv, ... | Authors: | Xian, Y, Yuan, M, Wilson, I.A. | Deposit date: | 2023-07-12 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (5.75 Å) | Cite: | Triple tandem trimer immunogens for HIV-1 and influenza nucleic acid-based vaccines. Npj Vaccines, 9, 2024
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8IP0
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![BU of 8ip0 by Molmil](/molmil-images/mine/8ip0) | Cryo-EM structure of type I-B Cascade bound to a PAM-containing dsDNA target at 3.6 angstrom resolution | Descriptor: | CRISPR associated protein Cas11b, DNA (41-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), ... | Authors: | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | Deposit date: | 2023-03-13 | Release date: | 2024-03-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and genome editing of type I-B CRISPR-Cas. Nat Commun, 15, 2024
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8IKX
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![BU of 8ikx by Molmil](/molmil-images/mine/8ikx) | An Arabidopsis polygalacturonase PGLR | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Pectin lyase-like superfamily protein, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Xiao, Y, Chai, J. | Deposit date: | 2023-03-01 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | A plant mechanism of hijacking pathogen virulence factors to trigger innate immunity. Science, 383, 2024
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8IKW
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![BU of 8ikw by Molmil](/molmil-images/mine/8ikw) | A complex structure of PGIP-PG | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Endo-polygalacturonase, ... | Authors: | Xiao, Y, Chai, J. | Deposit date: | 2023-03-01 | Release date: | 2024-02-07 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.94 Å) | Cite: | A plant mechanism of hijacking pathogen virulence factors to trigger innate immunity. Science, 383, 2024
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1T7B
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![BU of 1t7b by Molmil](/molmil-images/mine/1t7b) | Crystal structure of mutant Lys8Gln of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | Descriptor: | Alpha-like neurotoxin BmK-I | Authors: | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | Deposit date: | 2004-05-09 | Release date: | 2004-09-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins J.Mol.Biol., 341, 2004
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5KKB
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![BU of 5kkb by Molmil](/molmil-images/mine/5kkb) | Structure of mouse Golgi alpha-1,2-mannosidase IA and Man9GlcNAc2-PA complex | Descriptor: | 1,4-BUTANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 3-PYRIDINIUM-1-YLPROPANE-1-SULFONATE, ... | Authors: | Xiang, Y, Moremen, K.W. | Deposit date: | 2016-06-21 | Release date: | 2016-12-07 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (1.774 Å) | Cite: | Substrate recognition and catalysis by GH47 alpha-mannosidases involved in Asn-linked glycan maturation in the mammalian secretory pathway. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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1T7A
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![BU of 1t7a by Molmil](/molmil-images/mine/1t7a) | Crystal structure of mutant Lys8Asp of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | Descriptor: | Alpha-like neurotoxin BmK-I | Authors: | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | Deposit date: | 2004-05-08 | Release date: | 2004-09-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins J.Mol.Biol., 341, 2004
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1T7E
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![BU of 1t7e by Molmil](/molmil-images/mine/1t7e) | Crystal structure of mutant Pro9Ser of scorpion alpha-like neurotoxin BmK M1 from Buthus martensii Karsch | Descriptor: | Alpha-like neurotoxin BmK-I, PHOSPHATE ION | Authors: | Xiang, Y, Guan, R.J, He, X.L, Wang, C.G, Wang, M, Zhang, Y, Sundberg, E.J, Wang, D.C. | Deposit date: | 2004-05-09 | Release date: | 2004-09-07 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Structural Mechanism Governing Cis and Trans Isomeric States and an Intramolecular Switch for Cis/Trans Isomerization of a Non-proline Peptide Bond Observed in Crystal Structures of Scorpion Toxins J.Mol.Biol., 341, 2004
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2MXU
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![BU of 2mxu by Molmil](/molmil-images/mine/2mxu) | 42-Residue Beta Amyloid Fibril | Descriptor: | Amyloid beta A4 protein | Authors: | Xiao, Y, Ma, B, McElheny, D, Parthasarathy, S, Long, F, Hoshi, M, Nussinov, R, Ishii, Y. | Deposit date: | 2015-01-14 | Release date: | 2015-05-06 | Last modified: | 2024-05-01 | Method: | SOLID-STATE NMR | Cite: | A beta (1-42) fibril structure illuminates self-recognition and replication of amyloid in Alzheimer's disease. Nat.Struct.Mol.Biol., 22, 2015
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8H7Q
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![BU of 8h7q by Molmil](/molmil-images/mine/8h7q) | Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution | Descriptor: | CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ... | Authors: | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | Deposit date: | 2022-10-20 | Release date: | 2023-10-25 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM structure of Synechocystis sp. PCC6714 Cascade at 3.8 angstrom resolution To Be Published
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8H67
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![BU of 8h67 by Molmil](/molmil-images/mine/8h67) | type I-B Cascade bound to a PAM-containing dsDNA target at 3.8 angstrom resolution. | Descriptor: | CRISPR RNA, CRISPR associated protein Cas11b, CRISPR associated protein Cas5, ... | Authors: | Xiao, Y, Lu, M, Yu, C, Zhang, Y. | Deposit date: | 2022-10-15 | Release date: | 2024-05-01 | Last modified: | 2024-05-22 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Structure and genome editing of type I-B CRISPR-Cas. Nat Commun, 15, 2024
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8D6J
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8D71
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![BU of 8d71 by Molmil](/molmil-images/mine/8d71) | Human Ago2 bound to miR122(21nt) | Descriptor: | MAGNESIUM ION, Protein argonaute-2, miR-122-21nt | Authors: | Xiao, Y, MacRae, I. | Deposit date: | 2022-06-07 | Release date: | 2023-05-03 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength. Embo Rep., 24, 2023
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