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PDB: 146 件

7DH3
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The co-crystal structure of DYRK2 with a small molecule inhibitor 5
分子名称: 2,7-dimethoxy-9-piperidin-4-ylsulfanyl-acridine, Dual specificity tyrosine-phosphorylation-regulated kinase 2
著者Wei, T, Xiao, J.
登録日2020-11-12
公開日2021-11-17
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献The co-crystal structure of DYRK2 with a small molecule inhibitor 5
To Be Published
4U7T
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Crystal structure of DNMT3A-DNMT3L in complex with histone H3
分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Guo, X, Wang, L, Yin, X, Li, J, Xiao, J, He, S, Wang, J, Xu, Y.
登録日2014-07-31
公開日2014-11-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
4U7P
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Crystal structure of DNMT3A-DNMT3L complex
分子名称: DNA (cytosine-5)-methyltransferase 3-like, DNA (cytosine-5)-methyltransferase 3A, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Wang, L, Guo, X, Li, J, Xiao, J, Yin, X, He, S, Wang, J, Xu, Y.
登録日2014-07-31
公開日2014-11-12
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (3.821 Å)
主引用文献Structural insight into autoinhibition and histone H3-induced activation of DNMT3A
Nature, 517, 2015
8Z0T
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Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Du, S, Deng, M.J, Xiao, J.Y.
登録日2024-04-10
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Structure of the human ige-fc bound to its high affinity receptor fc(epsilon)
To Be Published
8Y81
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Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ...
著者Du, S, Deng, M.J, Xiao, J.Y.
登録日2024-02-05
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Structure of the ige-fc bound to its high affinity receptor fc(epsilon)ri
To Be Published
5Y96
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Crystal structure of ANXUR1 extracellular domain from Arabidopsis thaliana
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-like protein kinase ANXUR1
著者Du, S, Xiao, J.Y.
登録日2017-08-22
公開日2018-02-28
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structures of the extracellular domains of the CrRLK1L receptor-like kinases ANXUR1 and ANXUR2
Protein Sci., 27, 2018
5YH0
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The structure of DrFam20C1
分子名称: DrFam20C1
著者Zhang, H, Xiao, J.
登録日2017-09-27
公開日2018-04-11
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
8K2O
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Crystal structure of Fhb7-M10
分子名称: Fhb7-M10
著者Yang, J, Lei, X.G, Xiao, J.Y.
登録日2023-07-13
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7.
Jacs Au, 4, 2024
8K2P
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Crystal structure of CtGST-F76A
分子名称: Glutathione S-transferase
著者Yang, J, Xiao, J.Y, Lei, X.G.
登録日2023-07-13
公開日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Enzymatic Degradation of Deoxynivalenol with the Engineered Detoxification Enzyme Fhb7.
Jacs Au, 4, 2024
7E88
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Crystal structure of the SARS-CoV-2 S RBD in complex with BD-515 Fab
分子名称: BD-515 Fab Heavy Chain, BD-515 Fab Light Chain, Spike protein S1
著者Gao, C, Wei, Y, Xiao, J.
登録日2021-03-01
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.14 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
8Y84
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Structure of the high affinity receptor fc(epsilon)ri TM
分子名称: CHOLESTEROL HEMISUCCINATE, High affinity immunoglobulin epsilon receptor subunit alpha, High affinity immunoglobulin epsilon receptor subunit beta, ...
著者Du, S, Deng, M.J, Xiao, J.Y.
登録日2024-02-05
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (2.98 Å)
主引用文献Structure of the high affinity receptor fc(epsilon)ri TM
To Be Published
5ZTN
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The crystal structure of human DYRK2 in complex with Curcumin
分子名称: (1Z,4Z,6E)-5-hydroxy-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,4,6-trien-3-one, Dual specificity tyrosine-phosphorylation-regulated kinase 2
著者Ji, C.G, Xiao, J.Y.
登録日2018-05-04
公開日2018-07-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.496 Å)
主引用文献Ancient drug curcumin impedes 26S proteasome activity by direct inhibition of dual-specificity tyrosine-regulated kinase 2.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
6LXW
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BU of 6lxw by Molmil
Cryo-EM structure of human secretory immunoglobulin A in complex with the N-terminal domain of SpsA
分子名称: Immunoglobulin J chain, Interleukin-2,Immunoglobulin heavy constant alpha 1, Polymeric immunoglobulin receptor, ...
著者Wang, Y, Wang, G, Li, Y, Xiao, J.
登録日2020-02-12
公開日2020-05-27
最終更新日2020-07-22
実験手法ELECTRON MICROSCOPY (3.27 Å)
主引用文献Structural insights into secretory immunoglobulin A and its interaction with a pneumococcal adhesin.
Cell Res., 30, 2020
5X83
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Structure of DCC FN456 domains
分子名称: Netrin receptor DCC
著者Finci, F.I, Xiao, J, Wang, J.
登録日2017-02-28
公開日2017-09-06
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.997 Å)
主引用文献Structure of unliganded membrane-proximal domains FN4-FN5-FN6 of DCC
Protein Cell, 8, 2017
5Y92
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Crystal structure of ANXUR2 extracellular domain from Arabidopsis thaliana
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Receptor-like protein kinase ANXUR2, ...
著者Du, S, Xiao, J.Y.
登録日2017-08-22
公開日2018-02-28
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.004 Å)
主引用文献Crystal structures of the extracellular domains of the CrRLK1L receptor-like kinases ANXUR1 and ANXUR2
Protein Sci., 27, 2018
5YH3
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The structure of hFam20C and hFam20A complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Extracellular serine/threonine protein kinase FAM20C, Pseudokinase FAM20A
著者Zhu, Q, Xiao, J.
登録日2017-09-27
公開日2018-04-25
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
5YH2
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The structure of DrFam20C1 and hFam20A complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Family with sequence similarity 20, member Ca, ...
著者Zhang, H, Xiao, J.
登録日2017-09-27
公開日2018-04-11
最終更新日2018-04-25
実験手法X-RAY DIFFRACTION (3.55 Å)
主引用文献Structure and evolution of the Fam20 kinases
Nat Commun, 9, 2018
7E7Y
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BU of 7e7y by Molmil
Crystal structure of the SARS-CoV-2 S RBD in complex with BD-623 Fab
分子名称: BD-623 Fab H, BD-623 Fab L, Spike protein S1
著者Wei, Y, Xiao, J.
登録日2021-02-28
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E8C
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SARS-CoV-2 S-6P in complex with 9 Fabs
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.16 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
8JFK
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PhK holoenzyme in inactive state, muscle isoform
分子名称: Calmodulin-1, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ...
著者Yang, X.K, Xiao, J.Y.
登録日2023-05-18
公開日2024-04-03
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Architecture and activation of human muscle phosphorylase kinase.
Nat Commun, 15, 2024
8JFL
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PhK holoenzyme in active state, muscle isoform
分子名称: ADENOSINE-5'-DIPHOSPHATE, FARNESYL, Phosphorylase b kinase gamma catalytic chain, ...
著者Yang, X.K, Xiao, J.Y.
登録日2023-05-18
公開日2024-04-03
最終更新日2024-04-10
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Architecture and activation of human muscle phosphorylase kinase.
Nat Commun, 15, 2024
5Z5K
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Structure of the DCC-Draxin complex
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Draxin, ...
著者Liu, Y, Xiao, J, Wang, J.
登録日2018-01-18
公開日2018-06-20
最終更新日2021-03-10
実験手法X-RAY DIFFRACTION (2.493 Å)
主引用文献Structural Basis for Draxin-Modulated Axon Guidance and Fasciculation by Netrin-1 through DCC.
Neuron, 97, 2018
7E7X
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SARS-CoV-2 Spike Protein N terminal domain in Complex with N11 Fab
分子名称: N11 Fab Light chain, N11 Fab heavy chain, Spike protein S1
著者Zhang, Z, Shuo, D, Xiao, J.
登録日2021-02-28
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E8F
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SARS-CoV-2 NTD in complex with N9 Fab
分子名称: 368-2 H, 368-2 L, 604 H, ...
著者Du, S, Xiao, J, Zhang, Z.
登録日2021-03-01
公開日2021-06-09
最終更新日2021-07-14
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021
7E86
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Crystal structure of the SARS-CoV-2 S RBD in complex with BD-508 Fab
分子名称: BD-508 Fab Heavy Chain, BD-508 Fab Light Chain, Spike protein S1
著者Gao, C, Xiao, J.
登録日2021-03-01
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Humoral immune response to circulating SARS-CoV-2 variants elicited by inactivated and RBD-subunit vaccines.
Cell Res., 31, 2021

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