8JFL

PhK holoenzyme in active state, muscle isoform

Summary for 8JFL

Entry DOI	10.2210/pdb8jfl/pdb
EMDB information	36213
Descriptor	Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform, Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform, Phosphorylase b kinase regulatory subunit beta, ... (5 entities in total)
Functional Keywords	glycogen phosphorylase b kinase, muscle isoform, ca2+ active state, cytosolic protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	12
Total formula weight	1233707.96
Authors	Yang, X.K.,Xiao, J.Y. (deposition date: 2023-05-18, release date: 2024-04-03, Last modification date: 2024-04-10)
Primary citation	Yang, X.,Zhu, M.,Lu, X.,Wang, Y.,Xiao, J. Architecture and activation of human muscle phosphorylase kinase. Nat Commun, 15:2719-2719, 2024 Cited by PubMed: 38548794 DOI: 10.1038/s41467-024-47049-2 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.9 Å)

Structure validation