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PDB: 146 件

7CHF
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Crystal structure of the SARS-CoV-2 RBD in complex with BD-604 Fab and BD-368-2 Fab
分子名称: BD-368-2 Fab heavy chain, BD-368-2 Fab light chain, BD-604 Fab heavy chain, ...
著者Xiao, J, Zhu, Q.
登録日2020-07-05
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.674 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
7CHE
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Crystal structure of the SARS-CoV-2 RBD in complex with BD-236 Fab and BD-368-2 Fab
分子名称: BD-236 Fab heavy chain, BD-236 Fab light chain, BD-368-2 Fab heavy chain, ...
著者Xiao, J, Zhu, Q.
登録日2020-07-05
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.416 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
7CHB
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Crystal structure of the SARS-CoV-2 RBD in complex with BD-236 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BD-236 Fab heavy chain, BD-236 Fab light chain, ...
著者Xiao, J, Zhu, Q.
登録日2020-07-05
公開日2020-09-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.
Cell, 183, 2020
6KVA
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Structure of anti-hCXCR2 abN48-2 in complex with its CXCR2 epitope
分子名称: 1,2-ETHANEDIOL, Peptide from C-X-C chemokine receptor type 2, heavy chain, ...
著者Xiang, J.C, Yan, L, Yang, B, Wilson, I.A.
登録日2019-09-03
公開日2020-09-09
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Selection of a picomolar antibody that targets CXCR2-mediated neutrophil activation and alleviates EAE symptoms.
Nat Commun, 12, 2021
7VN9
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Crystal structure of human coronavirus 229E spike protein receptor-binding domain in complex with C04 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, C04 Fab heavy chain, ...
著者Xiang, J.C, Yang, B.
登録日2021-10-10
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (4.49 Å)
主引用文献Antigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein.
Commun Biol, 5, 2022
7VMZ
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Crystal structure of a human Coronavirus 229E antibody C04 Fab
分子名称: C04 Fab Heavy Chain, C04 Fab Light Chain
著者Xiang, J.C, Yang, B.
登録日2021-10-10
公開日2022-10-12
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Antigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein.
Commun Biol, 5, 2022
7VNG
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BU of 7vng by Molmil
Crystal structure of human coronavirus 229E spike protein receptor-binding domain in complex with S11 Fab
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, S11 Fab heavy chain, S11 Fab light chain, ...
著者Xiang, J.C, Zhao, W.W, Yang, B.
登録日2021-10-11
公開日2022-10-26
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献Antigenic mapping reveals sites of vulnerability on alpha-HCoV spike protein.
Commun Biol, 5, 2022
1U37
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BU of 1u37 by Molmil
Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Conformation of the Tandem PDZ Domains
分子名称: amyloid beta A4 precursor protein-binding, family A, member 1
著者Feng, W, Long, J.-F, Chan, L.-N, He, C, Fu, A, Xia, J, Ip, N.Y, Zhang, M.
登録日2004-07-21
公開日2005-07-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem
Nat.Struct.Mol.Biol., 12, 2005
1U39
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Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Conformation of the Tandem PDZ Domains
分子名称: amyloid beta A4 precursor protein-binding, family A, member 1
著者Feng, W, Long, J.-F, Chan, L.-N, He, C, Fu, A, Xia, J, Ip, N.Y, Zhang, M.
登録日2004-07-21
公開日2005-07-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem
Nat.Struct.Mol.Biol., 12, 2005
1QCR
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CRYSTAL STRUCTURE OF BOVINE MITOCHONDRIAL CYTOCHROME BC1 COMPLEX, ALPHA CARBON ATOMS ONLY
分子名称: PROTOPORPHYRIN IX CONTAINING FE, UBIQUINOL CYTOCHROME C OXIDOREDUCTASE
著者Xia, D, Yu, C.A, Kim, H, Xia, J.Z, Kachurin, A, Zhang, L, Yu, L, Deisenhofer, J.
登録日1997-05-17
公開日1998-10-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria.
Science, 277, 1997
5GJA
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Crystal structure of Arabidopsis thaliana ACO2 in complex with 2-PA
分子名称: 1-aminocyclopropane-1-carboxylate oxidase 2, PYRIDINE-2-CARBOXYLIC ACID, ZINC ION
著者Sun, X.Z, Li, Y.X, He, W.R, Ji, C.G, Xia, P.X, Wang, Y.C, Du, S, Li, H.J, Raikhel, N, Xiao, J.Y, Guo, H.W.
登録日2016-06-28
公開日2017-05-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase.
Nat Commun, 8, 2017
5GJ9
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Crystal structure of Arabidopsis thaliana ACO2 in complex with POA
分子名称: 1-aminocyclopropane-1-carboxylate oxidase 2, PYRAZINE-2-CARBOXYLIC ACID, ZINC ION
著者Sun, X.Z, Li, Y.X, He, W.R, Ji, C.G, Xia, P.X, Wang, Y.C, Du, S, Li, H.J, Raikhel, N, Xiao, J.Y, Guo, H.W.
登録日2016-06-28
公開日2017-05-10
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Pyrazinamide and derivatives block ethylene biosynthesis by inhibiting ACC oxidase.
Nat Commun, 8, 2017
1XJW
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BU of 1xjw by Molmil
The Structure of E. coli Aspartate Transcarbamoylase Q137A Mutant in The R-State
分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ...
著者Stieglitz, K.A, Alam, N, Xia, J, Gourinath, S, Tsuruta, H, Kantrowitz, E.R.
登録日2004-09-25
公開日2005-05-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.71 Å)
主引用文献A Single Amino Acid Substitution in the Active Site of Escherichia coli Aspartate Transcarbamoylase Prevents the Allosteric Transition.
J.Mol.Biol., 349, 2005
2PKU
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Solution structure of PICK1 PDZ in complex with the carboxyl tail peptide of GluR2
分子名称: PRKCA-binding protein, peptide (GLU)(SER)(VAL)(LYS)(ILE)
著者Pan, L, Wu, H, Shen, C, Shi, Y, Xia, J, Zhang, M.
登録日2007-04-18
公開日2007-11-20
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes
Embo J., 26, 2007
7EQ4
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BU of 7eq4 by Molmil
Crystal Structure of the N-terminus of Nonstructural protein 1 from SARS-CoV-2
分子名称: Host translation inhibitor nsp1
著者Liu, Y, Ke, Z, Hu, H, Zhao, K, Xiao, J, Xia, Y, Li, Y.
登録日2021-04-29
公開日2021-06-09
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Structural Basis and Function of the N Terminus of SARS-CoV-2 Nonstructural Protein 1.
Microbiol Spectr, 9, 2021
1U38
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BU of 1u38 by Molmil
Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Conformation of the Tandem PDZ Domains
分子名称: PVYI, amyloid beta A4 precursor protein-binding, family A, ...
著者Feng, W, Long, J.-F, Chan, L.-N, He, C, Fu, A, Xia, J, Ip, N.Y, Zhang, M.
登録日2004-07-21
公開日2005-07-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem
Nat.Struct.Mol.Biol., 12, 2005
1U3B
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BU of 1u3b by Molmil
Auto-inhibition Mechanism of X11s/Mints Family Scaffold Proteins Revealed by the Closed Conformation of the Tandem PDZ Domains
分子名称: amyloid beta A4 precursor protein-binding, family A, member 1
著者Feng, W, Long, J.-F, Chan, L.-N, He, C, Fu, A, Xia, J, Ip, N.Y, Zhang, M.
登録日2004-07-21
公開日2005-07-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Autoinhibition of X11/Mint scaffold proteins revealed by the closed conformation of the PDZ tandem
Nat.Struct.Mol.Biol., 12, 2005
3D7S
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BU of 3d7s by Molmil
Crystal structure of Wild-Type E. Coli Asparate Transcarbamoylase at pH 8.5 at 2.80 A Resolution
分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ZINC ION
著者Stieglitz, K.A, Xia, J, Kantrowitz, E.R.
登録日2008-05-21
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The first high pH structure of Escherichia coli aspartate transcarbamoylase.
Proteins, 74, 2008
2H3E
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BU of 2h3e by Molmil
Structure of wild-type E. coli Aspartate Transcarbamoylase in the presence of N-phosphonacetyl-L-isoasparagine at 2.3A resolution
分子名称: (S)-4-AMINO-4-OXO-3-(2-PHOSPHONOACETAMIDO)BUTANOIC ACID, Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ...
著者Eldo, J, Cardia, J.P, O'Day, E.M, Xia, J, Tsuruta, H, Kantrowitz, E.R.
登録日2006-05-22
公開日2006-10-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献N-Phosphonacetyl-l-isoasparagine a Potent and Specific Inhibitor of Escherichia coli Aspartate Transcarbamoylase.
J.Med.Chem., 49, 2006
2FZC
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The Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.10 Resolution
分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Heng, S, Stieglitz, K.A, Eldo, J, Xia, J, Cardia, J.P, Kantrowitz, E.R.
登録日2006-02-09
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献T-state Inhibitors of E. coli Aspartate Transcarbamoylase that Prevent the Allosteric Transition.
Biochemistry, 45, 2006
2FZG
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The Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.25 Resolution
分子名称: Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, CYTIDINE-5'-TRIPHOSPHATE, ...
著者Heng, S, Stieglitz, K.A, Eldo, J, Xia, J, Cardia, J.P, Kantrowitz, E.R.
登録日2006-02-09
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献T-state Inhibitors of E. coli Aspartate Transcarbamoylase that Prevent the Allosteric Transition.
Biochemistry, 45, 2006
2FZK
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The Structure of Wild-Type E. Coli Aspartate Transcarbamoylase in Complex with Novel T State Inhibitors at 2.50 Resolution
分子名称: 3,5-BIS[(PHOSPHONOACETYL)AMINO]BENZOIC ACID, Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ...
著者Heng, S, Stieglitz, K.A, Eldo, J, Xia, J, Cardia, J.P, Kantrowitz, E.R.
登録日2006-02-09
公開日2006-08-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献T-state Inhibitors of E. coli Aspartate Transcarbamoylase that Prevent the Allosteric Transition.
Biochemistry, 45, 2006
2IPO
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E. coli Aspartate Transcarbamoylase complexed with N-phosphonacetyl-L-asparagine
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, ...
著者Cardia, J.P, Eldo, J, Xia, J, O'Day, E.M, Tsuruta, H, Kantrowitz, E.R.
登録日2006-10-12
公開日2007-08-28
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Use of L-asparagine and N-phosphonacetyl-L-asparagine to investigate the linkage of catalysis and homotropic cooperativity in E. coli aspartate transcarbomoylase.
Proteins, 71, 2008
8JH5
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Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the Naproxen-bound state
分子名称: (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid, Auxin efflux carrier component 1, nanobody
著者Sun, L, Liu, X, Yang, Z, Xia, J.
登録日2023-05-22
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the Naproxen-bound state
To be published
7Y9V
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Structure of the auxin exporter PIN1 in Arabidopsis thaliana in the IAA-bound state
分子名称: 1H-INDOL-3-YLACETIC ACID, Auxin efflux carrier component 1, nanobody
著者Sun, L, Liu, X, Yang, Z, Xia, J.
登録日2022-06-26
公開日2022-09-07
最終更新日2022-09-28
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into auxin recognition and efflux by Arabidopsis PIN1.
Nature, 609, 2022

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