2H3E

Structure of wild-type E. coli Aspartate Transcarbamoylase in the presence of N-phosphonacetyl-L-isoasparagine at 2.3A resolution

Summary for 2H3E

Entry DOI	10.2210/pdb2h3e/pdb
Related	1D09
Descriptor	Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, (S)-4-AMINO-4-OXO-3-(2-PHOSPHONOACETAMIDO)BUTANOIC ACID, ... (5 entities in total)
Functional Keywords	cooperativity, transferase
Biological source	Escherichia coli More
Total number of polymer chains	4
Total formula weight	103600.55
Authors	Eldo, J.,Cardia, J.P.,O'Day, E.M.,Xia, J.,Tsuruta, H.,Kantrowitz, E.R. (deposition date: 2006-05-22, release date: 2006-10-17, Last modification date: 2023-08-30)
Primary citation	Eldo, J.,Cardia, J.P.,O'day, E.M.,Xia, J.,Tsuruta, H.,Kantrowitz, E.R. N-Phosphonacetyl-l-isoasparagine a Potent and Specific Inhibitor of Escherichia coli Aspartate Transcarbamoylase. J.Med.Chem., 49:5932-5938, 2006 Cited by PubMed: 17004708 DOI: 10.1021/jm0607294 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation