1XJW

The Structure of E. coli Aspartate Transcarbamoylase Q137A Mutant in The R-State

Summary for 1XJW

Entry DOI	10.2210/pdb1xjw/pdb
Related	1D09
Descriptor	Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N-(PHOSPHONACETYL)-L-ASPARTIC ACID, ... (5 entities in total)
Functional Keywords	allosteric enzyme, polar contacts, electrostatics, small angle x-ray scattering, domain closure, intersubunit interactions, transferase-transferase regulator complex, transferase/transferase regulator
Biological source	Escherichia coli More
Total number of polymer chains	4
Total formula weight	103488.42
Authors	Stieglitz, K.A.,Alam, N.,Xia, J.,Gourinath, S.,Tsuruta, H.,Kantrowitz, E.R. (deposition date: 2004-09-25, release date: 2005-05-24, Last modification date: 2023-08-23)
Primary citation	Stieglitz, K.A.,Pastra-Landis, S.C.,Xia, J.,Tsuruta, H.,Kantrowitz, E.R. A Single Amino Acid Substitution in the Active Site of Escherichia coli Aspartate Transcarbamoylase Prevents the Allosteric Transition. J.Mol.Biol., 349:413-423, 2005 Cited by PubMed: 15890205 DOI: 10.1016/j.jmb.2005.03.073 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.71 Å)

Structure validation