2IPO

E. coli Aspartate Transcarbamoylase complexed with N-phosphonacetyl-L-asparagine

Summary for 2IPO

Entry DOI	10.2210/pdb2ipo/pdb
Related	1D09 2IQE
Descriptor	Aspartate carbamoyltransferase catalytic chain, Aspartate carbamoyltransferase regulatory chain, N~2~-(PHOSPHONOACETYL)-L-ASPARAGINE, ... (7 entities in total)
Functional Keywords	aspartate transcarbamoylase, allosteric, inhibitor design, domain closure, transferase
Biological source	Escherichia coli More
Total number of polymer chains	4
Total formula weight	104069.04
Authors	Cardia, J.P.,Eldo, J.,Xia, J.,O'Day, E.M.,Tsuruta, H.,Kantrowitz, E.R. (deposition date: 2006-10-12, release date: 2007-08-28, Last modification date: 2023-08-30)
Primary citation	Cardia, J.P.,Eldo, J.,Xia, J.,O'Day, E.M.,Tsuruta, H.,Gryncel, K.R.,Kantrowitz, E.R. Use of L-asparagine and N-phosphonacetyl-L-asparagine to investigate the linkage of catalysis and homotropic cooperativity in E. coli aspartate transcarbomoylase. Proteins, 71:1088-1096, 2008 Cited by PubMed: 18004787 DOI: 10.1002/prot.21760 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.6 Å)

Structure validation