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PDB: 597 件

2WIN
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C3 convertase (C3bBb) stabilized by SCIN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, COMPLEMENT C3 BETA CHAIN, ...
著者Wu, J, Janssen, B.J, Gros, P.
登録日2009-05-13
公開日2009-06-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.9 Å)
主引用文献Structural and functional implications of the alternative complement pathway C3 convertase stabilized by a staphylococcal inhibitor.
Nat. Immunol., 10, 2009
5HVZ
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Crystal structure of smAKAP AKB domain bound RIa dimerization/docking (D/D) complex at 2.0 A resolution
分子名称: Small membrane A-kinase anchor protein, cAMP-dependent protein kinase type I-alpha regulatory subunit
著者Wu, J, Burgers, P.P, Bruystens, J, Heck, A.J.R, Taylor, S.S.
登録日2016-01-28
公開日2016-04-20
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of smAKAP and its regulation by PKA-mediated phosphorylation.
Febs J., 283, 2016
1MR1
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Crystal Structure of a Smad4-Ski Complex
分子名称: Mothers against decapentaplegic homolog 4, Ski oncogene, ZINC ION
著者Wu, J.-W, Krawitz, A.R, Chai, J, Li, W, Zhang, F, Luo, K, Shi, Y.
登録日2002-09-17
公開日2003-01-21
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural Mechanism of Smad4 Recognition by the Nuclear Oncoprotein Ski: Insights on Ski-mediated Repression of TGF-beta Signaling
Cell(Cambridge,Mass.), 111, 2002
2QVS
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BU of 2qvs by Molmil
Crystal Structure of Type IIa Holoenzyme of cAMP-dependent Protein Kinase
分子名称: cAMP-dependent protein kinase type II-alpha regulatory subunit, cAMP-dependent protein kinase, alpha-catalytic subunit
著者Wu, J, Brown, S.H.J, von Daake, S, Taylor, S.S.
登録日2007-08-08
公開日2007-10-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献PKA type IIalpha holoenzyme reveals a combinatorial strategy for isoform diversity.
Science, 318, 2007
7YRE
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Crystal structure of a bright green fluorescent protein (StayGold) with triple mutations (N137A, Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus
分子名称: 1,2-ETHANEDIOL, staygold(N137A,Q140S,Y187F)
著者Wu, J, Wang, F, Gui, W, Cheng, W, Yang, Y.
登録日2022-08-09
公開日2023-08-16
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a bright green fluorescent protein (StayGold) with triple mutations (N137A, Q140S, Y187F) in jellyfish Cytaeis uchidae from Biortus
To Be Published
1YKS
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Crystal structure of yellow fever virus NS3 helicase
分子名称: Genome polyprotein [contains: Flavivirin protease NS3 catalytic subunit]
著者Wu, J, Bera, A.K, Kuhn, R.J, Smith, J.L.
登録日2005-01-18
公開日2005-08-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of the flavivirus helicase: implications for catalytic activity, protein interactions, and proteolytic processing.
J.Virol., 79, 2005
8FSE
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BU of 8fse by Molmil
Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain
分子名称: Integrin beta-2,Talin-1
著者Wu, J, Gao, T.
登録日2023-01-09
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation
Biorxiv, 2024
8FTB
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Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with a K306Q mutation
分子名称: Integrin beta-2,Talin-1
著者Wu, J, Gao, T.
登録日2023-01-11
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation
Biorxiv, 2024
8T0D
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Crystal structure of integrin beta-2 tail bound to the FERM-folded talin head domain with E269A/Y270A/K306Q triple mutation
分子名称: Integrin beta-2,Talin-1
著者Wu, J, Gao, T.
登録日2023-05-31
公開日2024-07-03
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structure of Talin Bound to beta 2 Integrin Unveils the Molecular Mechanism of Species-Specific Integrin Activation
Biorxiv, 2024
1ZTQ
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Crystal structure of the catalytic domain of MMP-13 complexed with WAY-033
分子名称: CALCIUM ION, Collagenase 3, N-({4'-[(1-BENZOFURAN-2-YLCARBONYL)AMINO]-1,1'-BIPHENYL-4-YL}SULFONYL)-L-VALINE, ...
著者Wu, J, Rush III, T.S, Hotchandani, R, Du, X, Geck, M, Collins, E, Xu, Z.B, Skotnicki, J, Levin, J.I, Lovering, F.
登録日2005-05-27
公開日2006-05-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of potent and selective MMP-13 inhibitors
Bioorg.Med.Chem.Lett., 15, 2005
3H0R
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Structure of trna-dependent amidotransferase gatcab from aquifex aeolicus
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ASPARAGINE, ...
著者Wu, J, Bu, W, Sheppard, K, Kitabatake, M, Soll, D, Smith, J.L.
登録日2009-04-10
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
J.Mol.Biol., 391, 2009
1M2M
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Crystal structure of E44A/E48A/E56A/D60A mutant of cytochrome b5
分子名称: PROTOPORPHYRIN IX CONTAINING FE, cytochrome b5
著者Wu, J, Wang, Y.-H, Gan, J.-H, Wang, W.-H, Sun, B.-Y, Huang, Z.-X, Xia, Z.-X.
登録日2002-06-24
公開日2003-03-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of Cytochrome b5 Mutated at the Charged Surface-Residues and Their Interactions with Cytochrome c
Chin.J.Chem., 20, 2002
3H0M
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Structure of trna-dependent amidotransferase gatcab from aquifex aeolicus
分子名称: Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, GLUTAMINE, Glutamyl-tRNA(Gln) amidotransferase subunit A, ...
著者Wu, J, Bu, W, Sheppard, K, Kitabatake, M, Soll, D, Smith, J.L.
登録日2009-04-09
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
J.Mol.Biol., 391, 2009
3H0L
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BU of 3h0l by Molmil
Structure of trna-dependent amidotransferase gatcab from aquifex aeolicus
分子名称: ADENOSINE-5'-DIPHOSPHATE, ASPARAGINE, Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B, ...
著者Wu, J, Bu, W, Sheppard, K, Kitabatake, M, Soll, D, Smith, J.L.
登録日2009-04-09
公開日2009-07-21
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Insights into tRNA-Dependent Amidotransferase Evolution and Catalysis from the Structure of the Aquifex aeolicus Enzyme
J.Mol.Biol., 391, 2009
1NE4
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BU of 1ne4 by Molmil
Crystal Structure of Rp-cAMP Binding R1a Subunit of cAMP-dependent Protein Kinase
分子名称: 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, cAMP-dependent protein kinase type I-alpha regulatory chain
著者Wu, J, Jones, J.M, Xuong, N.H, Taylor, S.S.
登録日2002-12-10
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
3D94
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Crystal structure of the insulin-like growth factor-1 receptor kinase in complex with PQIP
分子名称: 3-[cis-3-(4-methylpiperazin-1-yl)cyclobutyl]-1-(2-phenylquinolin-7-yl)imidazo[1,5-a]pyrazin-8-amine, CALCIUM ION, Insulin-like growth factor 1 receptor beta chain
著者Wu, J, Li, W, Miller, W.T, Hubbard, S.R.
登録日2008-05-26
公開日2008-07-29
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Small-molecule inhibition and activation-loop trans-phosphorylation of the IGF1 receptor
Embo J., 27, 2008
1JD6
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Crystal Structure of DIAP1-BIR2/Hid Complex
分子名称: APOPTOSIS 1 INHIBITOR, ZINC ION, head involution defective protein
著者Wu, J.W, Cocina, A.E, Chai, J, Hay, B.A, Shi, Y.
登録日2001-06-12
公開日2001-12-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides.
Mol.Cell, 8, 2001
1JD4
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Crystal Structure of DIAP1-BIR2
分子名称: APOPTOSIS 1 INHIBITOR, ZINC ION
著者Wu, J.W, Cocina, A.E, Chai, J, Hay, B.A, Shi, Y.
登録日2001-06-12
公開日2001-12-05
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides.
Mol.Cell, 8, 2001
1JD5
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Crystal Structure of DIAP1-BIR2/GRIM
分子名称: APOPTOSIS 1 INHIBITOR, ZINC ION, cell death protein GRIM
著者Wu, J.W, Cocina, A.E, Chai, J, Hay, B.A, Shi, Y.
登録日2001-06-12
公開日2001-12-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural analysis of a functional DIAP1 fragment bound to grim and hid peptides.
Mol.Cell, 8, 2001
1NE6
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Crystal structure of Sp-cAMP binding R1a subunit of cAMP-dependent protein kinase
分子名称: 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL, cAMP-dependent protein kinase type I-alpha regulatory chain
著者Wu, J, Jones, J.M, Xuong, N.H, Taylor, S.S.
登録日2002-12-10
公開日2004-01-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.
Biochemistry, 43, 2004
1ES1
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CRYSTAL STRUCTURE OF VAL61HIS MUTANT OF TRYPSIN-SOLUBILIZED FRAGMENT OF CYTOCHROME B5
分子名称: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
著者Wu, J, Gan, J.-H, Xia, Z.-X, Wang, Y.-H, Wang, W.-H, Xue, L.-L, Xie, Y, Huang, Z.-X.
登録日2000-04-07
公開日2000-08-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of recombinant trypsin-solubilized fragment of cytochrome b(5) and the structural comparison with Val61His mutant.
Proteins, 40, 2000
1EHB
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CRYSTAL STRUCTURE OF RECOMBINANT TRYPSIN-SOLUBILIZED FRAGMENT OF CYTOCHROME B5
分子名称: PROTEIN (CYTOCHROME B5), PROTOPORPHYRIN IX CONTAINING FE
著者Wu, J, Gan, J.-H, Xia, Z.-X, Wang, Y.-H, Wang, W.-H, Xue, L.-L, Xie, Y, Huang, Z.-X.
登録日2000-02-20
公開日2000-08-09
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of recombinant trypsin-solubilized fragment of cytochrome b(5) and the structural comparison with Val61His mutant.
Proteins, 40, 2000
8XB2
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Structure of radafaxine-bound state of the human Norepinephrine Transporter
分子名称: (2~{S},3~{S})-2-(3-chlorophenyl)-3,5,5-trimethyl-morpholin-2-ol, 2-acetamido-2-deoxy-beta-D-glucopyranose, GFP-MBP-solute carrier family 6 member 2,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter,Maltose/maltodextrin-binding periplasmic protein,Sodium-dependent noradrenaline transporter
著者Wu, J.X, Ji, W.M.
登録日2023-12-05
公開日2024-07-10
実験手法ELECTRON MICROSCOPY (3.04 Å)
主引用文献Substrate binding and inhibition mechanism of norepinephrine transporter
To Be Published
8XB4
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Structure of apo state of the human Norepinephrine Transporter
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GFP-MBP-solute carrier family 6 member 2
著者Wu, J.X, Ji, W.M.
登録日2023-12-05
公開日2024-06-26
実験手法ELECTRON MICROSCOPY (2.92 Å)
主引用文献Structural mechanism of substrate binding and inhibition of the human Norepinephrine Transporter
To Be Published
5IC0
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Structural analysis of a talin triple domain module
分子名称: 1,2-ETHANEDIOL, Talin-1
著者Wu, J, Chang, Y.-C.E, Zhang, H, Brennan, M.L.
登録日2016-02-22
公開日2016-05-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Structural and Functional Analysis of a Talin Triple-Domain Module Suggests an Alternative Talin Autoinhibitory Configuration.
Structure, 24, 2016

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件を2024-08-21に公開中

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