4MRB
| Wild Type Human Transthyretin pH 7.5 | 分子名称: | CALCIUM ION, Transthyretin | 著者 | Chen, W.J, Wood, S.P. | 登録日 | 2013-09-17 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Proc.Natl.Acad.Sci.USA, 111, 2014
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4MLQ
| Crystal structure of Bacillus megaterium porphobilinogen deaminase | 分子名称: | 3-[(5S)-5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]propanoic acid, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, ACETIC ACID, ... | 著者 | Azim, N, Deery, E, Warren, M.J, Erskine, P, Cooper, J.B, Coker, A, Wood, S.P, Akhtar, M. | 登録日 | 2013-09-06 | 公開日 | 2014-04-02 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Structural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of the Bacillus megaterium enzyme at near-atomic resolution. Acta Crystallogr.,Sect.D, 70, 2014
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4MRC
| Human Transthyretin Ser52Pro Mutant | 分子名称: | CALCIUM ION, Transthyretin | 著者 | Chen, W.J, Wood, S.P. | 登録日 | 2013-09-17 | 公開日 | 2014-01-08 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Proc.Natl.Acad.Sci.USA, 111, 2014
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4EGH
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4EGK
| Human Hsp90-alpha ATPase domain bound to Radicicol | 分子名称: | Heat shock protein HSP 90-alpha, RADICICOL | 著者 | Chen, W.J, Wood, S.P. | 登録日 | 2012-03-31 | 公開日 | 2012-05-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Fragment screening using capillary electrophoresis (CEfrag) for hit identification of heat shock protein 90 ATPase inhibitors. J Biomol Screen, 17, 2012
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4EGI
| Hsp90-alpha ATPase domain in complex with 2-Amino-4-ethylthio-6-methyl-1,3,5-triazine | 分子名称: | 4-(ethylsulfanyl)-6-methyl-1,3,5-triazin-2-amine, Heat shock protein HSP 90-alpha | 著者 | Chen, W.J, Wood, S.P. | 登録日 | 2012-03-31 | 公開日 | 2012-05-23 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Fragment screening using capillary electrophoresis (CEfrag) for hit identification of heat shock protein 90 ATPase inhibitors. J Biomol Screen, 17, 2012
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4NDD
| X-ray structure of a double mutant of calexcitin - a neuronal calcium-signalling protein | 分子名称: | CALCIUM ION, Calexcitin | 著者 | Erskine, P.T, Fokas, A, Muriithi, C, Razzall, E, Bowyer, A, Findlow, I.S, Werner, J.M, Wallace, B.A, Wood, S.P, Cooper, J.B. | 登録日 | 2013-10-25 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure-function studies of a neuronal calcium-signalling protein. Acta Crystallogr.,Sect.D, 71, 2015
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4NDC
| X-ray structure of a mutant (T188D) of calexcitin - a neuronal calcium-signalling protein | 分子名称: | CALCIUM ION, Calexcitin | 著者 | Erskine, P.T, Fokas, A, Muriithi, C, Razzall, E, Bowyer, A, Findlow, I.S, Werner, J.M, Wallace, B.A, Wood, S.P, Cooper, J.B. | 登録日 | 2013-10-25 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure-function studies of a neuronal calcium-signalling protein. Acta Crystallogr.,Sect.D, 71, 2015
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4NDB
| X-ray structure of a mutant (T61D) of calexcitin - a neuronal calcium-signalling protein | 分子名称: | CALCIUM ION, Calexcitin | 著者 | Erskine, P.T, Fokas, A, Muriithi, C, Razzall, E, Bowyer, A, Findlow, I.S, Werner, J.M, Wallace, B.A, Wood, S.P, Cooper, J.B. | 登録日 | 2013-10-25 | 公開日 | 2014-10-29 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure-function studies of a neuronal calcium-signalling protein. Acta Crystallogr.,Sect.D, 71, 2015
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3IPB
| Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (11 carbon linker). | 分子名称: | 2,2'-{undecane-1,11-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid, Transthyretin | 著者 | Kolstoe, S.E, Wood, S.P, Pepys, M.B. | 登録日 | 2009-08-17 | 公開日 | 2010-11-17 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proc.Natl.Acad.Sci.USA, 107, 2010
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3IPE
| Human Transthyretin (TTR) complexed with a palindromic bivalent amyloid inhibitor (7 carbon linker). | 分子名称: | 2,2'-{heptane-1,7-diylbis[oxy(3,5-dichlorobenzene-4,1-diyl)imino]}dibenzoic acid, Transthyretin | 著者 | Kolstoe, S.E, Wood, S.P, Pepys, M.B. | 登録日 | 2009-08-17 | 公開日 | 2010-11-17 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Trapping of palindromic ligands within native transthyretin prevents amyloid formation. Proc.Natl.Acad.Sci.USA, 107, 2010
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3KQR
| The structure of serum amyloid p component bound to phosphoethanolamine | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER, ... | 著者 | Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B. | 登録日 | 2009-11-17 | 公開日 | 2010-12-08 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. J.Mol.Recognit., 24, 2011
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3L2Y
| The structure of C-reactive protein bound to phosphoethanolamine | 分子名称: | C-reactive protein, CALCIUM ION, PHOSPHORIC ACID MONO-(2-AMINO-ETHYL) ESTER | 著者 | Mikolajek, H, Kolstoe, S.E, Wood, S.P, Pepys, M.B. | 登録日 | 2009-12-15 | 公開日 | 2010-12-08 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis of ligand specificity in the human pentraxins, C-reactive protein and serum amyloid P component. J.Mol.Recognit., 24, 2011
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