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PDB: 871 件

2NTF
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Crystal Structure of a Quorum-Quenching Antibody in Complex with an N-Acyl-L-Homoserine Lactone Analog
分子名称: 3-OXO-N-[(3S)-2-OXOPYRROLIDIN-3-YL]DODECANAMIDE, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
著者Debler, E.W, Wilson, I.A.
登録日2006-11-07
公開日2007-05-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.18 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
2OJZ
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Anti-DNA antibody ED10
分子名称: Fab ED10 heavy chain, Fab ED10 light chain
著者Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
登録日2007-01-15
公開日2007-06-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.73 Å)
主引用文献Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
2O5X
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Crystal structure of 1E9 LeuH47Trp/ArgH100Trp, an engineered Diels-Alderase Fab with nM steroid-binding affinity
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, chimeric antibody Fab 1E9-DB3
著者Verdino, P, Wilson, I.A.
登録日2006-12-06
公開日2007-12-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2O5Z
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Crystal structure of the 1E9 LeuH47Trp/ArgH100Trp Fab 5-beta-androstane-3,17-dione complex
分子名称: 5-BETA-ANDROSTANE-3,17-DIONE, SULFATE ION, chimeric antibody Fab 1E9-DB3
著者Verdino, P, Wilson, I.A.
登録日2006-12-06
公開日2007-12-18
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Closely related antibody receptors exploit fundamentally different strategies for steroid recognition.
Proc.Natl.Acad.Sci.Usa, 105, 2008
2OK0
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Fab ED10-DNA complex
分子名称: 5'-D(*TP*C)-3', Fab ED10 heavy chain, Fab ED10 light chain
著者Stanfield, R.L, Sanguineti, S, Wilson, I.A, de Prat-Gay, G.
登録日2007-01-15
公開日2007-06-12
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Specific recognition of a DNA immunogen by its elicited antibody
J.Mol.Biol., 370, 2007
3IMR
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Transthyretin in complex with (E)-2,6-dibromo-4-(2,6-dichlorostyryl)phenol
分子名称: 2,6-dibromo-4-[(E)-2-(2,6-dichlorophenyl)ethenyl]phenol, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
2OQJ
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Crystal structure analysis of Fab 2G12 in complex with peptide 2G12.1
分子名称: Fab 2G12 heavy chain, Fab 2G12 light chain, peptide 2G12.1 (ACPPSHVLDMRSGTCLAAEGK)
著者Calarese, D.A, Stanfield, R.L, Menendez, A, Scott, J.K, Wilson, I.A.
登録日2007-01-31
公開日2008-01-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献A peptide inhibitor of HIV-1 neutralizing antibody 2G12 is not a structural mimic of the natural carbohydrate epitope on gp120.
Faseb J., 22, 2008
3IMW
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Transthyretin in complex with (E)-2,6-dibromo-4-(2,6-dimethoxystyryl)aniline
分子名称: 2,6-dibromo-4-[(E)-2-(2,6-dimethoxyphenyl)ethenyl]aniline, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.31 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
2OP4
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Crystal Structure of Quorum-Quenching Antibody 1G9
分子名称: 1,2-ETHANEDIOL, Murine Antibody Fab RS2-1G9 IGG1 Heavy Chain, Murine Antibody Fab RS2-1G9 Lambda Light Chain
著者Kirchdoerfer, R.N, Debler, E.W, Wilson, I.A.
登録日2007-01-26
公開日2007-05-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Crystal Structures of a Quorum-quenching Antibody.
J.Mol.Biol., 368, 2007
3IMS
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Transthyretin in complex with 2,6-dibromo-4-(2,6-dichlorophenethyl)phenol
分子名称: 2,6-dibromo-4-[2-(2,6-dichlorophenyl)ethyl]phenol, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
2I27
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Crystal Structure Analysis of the Nurse Shark New Antigen Receptor Ancestral variable domain
分子名称: New Antigen Receptor Ancestral
著者Stanfield, R.L, Wilson, I.A.
登録日2006-08-15
公開日2007-03-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.
J.Mol.Biol., 367, 2007
2I24
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BU of 2i24 by Molmil
Crystal structure analysis of the nurse shark New Antigen Receptor PBLA8 variable domain
分子名称: CHLORIDE ION, New Antigen Receptor PBLA8
著者Stanfield, R.L, Wilson, I.A.
登録日2006-08-15
公開日2007-03-06
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding
J.Mol.Biol., 367, 2007
3IMU
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BU of 3imu by Molmil
Transthyretin in complex with (E)-4-(3-aminostyryl)-2,6-dibromoaniline
分子名称: 4-[(E)-2-(3-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
2I26
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BU of 2i26 by Molmil
Crystal structure analysis of the nurse shark new antigen receptor ancestral variable domain in complex with lysozyme
分子名称: Lysozyme C, New Antigen Receptor Ancestral, SULFATE ION
著者Stanfield, R.L, Wilson, I.A.
登録日2006-08-15
公開日2007-03-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding.
J.Mol.Biol., 367, 2007
3IMV
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BU of 3imv by Molmil
Transthyretin in complex with (E)-4-(4-aminostyryl)-2,6-dibromoaniline
分子名称: 4-[(E)-2-(4-aminophenyl)ethenyl]-2,6-dibromoaniline, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2009-08-11
公開日2010-01-12
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献A substructure combination strategy to create potent and selective transthyretin kinetic stabilizers that prevent amyloidogenesis and cytotoxicity.
J.Am.Chem.Soc., 132, 2010
2I25
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BU of 2i25 by Molmil
Crystal structure analysis of the nurse shark New antigen Receptor PBLA8 variable domain in complex with lysozyme
分子名称: Lysozyme C, New Antigen Receptor PBLA8
著者Stanfield, R.L, Wilson, I.A.
登録日2006-08-15
公開日2007-03-06
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Maturation of Shark Single-domain (IgNAR) Antibodies: Evidence for Induced-fit Binding
J.Mol.Biol., 367, 2007
3J5M
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BU of 3j5m by Molmil
Cryo-EM structure of the BG505 SOSIP.664 HIV-1 Env trimer with 3 PGV04 Fabs
分子名称: BG505 SOSIP gp120, BG505 SOSIP gp41, PGV04 heavy chain, ...
著者Lyumkis, D, Julien, J.-P, Wilson, I.A, Ward, A.B.
登録日2013-10-26
公開日2013-11-13
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (5.8 Å)
主引用文献Cryo-EM structure of a fully glycosylated soluble cleaved HIV-1 envelope trimer.
Science, 342, 2013
2PRT
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BU of 2prt by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(*CP*AP*GP*AP*CP*GP*CP*CP*CP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*CP*GP*CP*GP*GP*GP*GP*GP*CP*GP*TP*CP*TP*G)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-05-04
公開日2008-03-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structure of the Wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2Q7Y
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Structure of the endogenous iNKT cell ligand iGb3 bound to mCD1d
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ...
著者Zajonc, D.M, Wilson, I.A, Teyton, L.
登録日2007-06-07
公開日2008-04-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structures of Mouse CD1d-iGb3 Complex and its Cognate Valpha14 T Cell Receptor Suggest a Model for Dual Recognition of Foreign and Self Glycolipids.
J.Mol.Biol., 377, 2008
2JP9
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Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DGP*DCP*DGP*DC)-3'), DNA (5'-D(P*DGP*DCP*DGP*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-04-30
公開日2007-10-30
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2QGE
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Human transthyretin (TTR) complexed with 2-(3,5-Dimethylphenyl)benzoxazole
分子名称: 2-(3,5-DIMETHYLPHENYL)-1,3-BENZOXAZOLE, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2007-06-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2JPA
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BU of 2jpa by Molmil
Structure of the Wilms Tumor Suppressor Protein Zinc Finger Domain Bound to DNA
分子名称: DNA (5'-D(P*DCP*DAP*DGP*DAP*DCP*DGP*DCP*DCP*DCP*DCP*DCP*DGP*DCP*DG)-3'), DNA (5'-D(P*DCP*DGP*DCP*DGP*DGP*DGP*DGP*DGP*DCP*DGP*DTP*DCP*DTP*DG)-3'), Wilms tumor 1, ...
著者Stoll, R, Lee, B.M, Debler, E.W, Laity, J.H, Wilson, I.A, Dyson, H.J, Wright, P.E.
登録日2007-05-01
公開日2007-10-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Structure of the wilms tumor suppressor protein zinc finger domain bound to DNA
J.Mol.Biol., 372, 2007
2QGB
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Human transthyretin (TTR) in Apo-form
分子名称: Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2007-06-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
2QGD
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Human transthyretin (TTR) complexed with 2-(3,5-Dibromo-4-hydroxyphenyl)benzoxazole
分子名称: 4-(1,3-BENZOXAZOL-2-YL)-2,6-DIBROMOPHENOL, Transthyretin
著者Connelly, S, Wilson, I.A.
登録日2007-06-28
公開日2008-02-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Biochemical and structural evaluation of highly selective 2-arylbenzoxazole-based transthyretin amyloidogenesis inhibitors.
J.Med.Chem., 51, 2008
3KU3
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Crystal structure of a H2N2 influenza virus hemagglutinin, avian like
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Xu, R, Wilson, I.A.
登録日2009-11-26
公開日2010-01-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structure, receptor binding, and antigenicity of influenza virus hemagglutinins from the 1957 H2N2 pandemic.
J.Virol., 84, 2010

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