5LOE
 
 | | Structure of full length Cody from Bacillus subtilis in complex with Ile | | Descriptor: | GTP-sensing transcriptional pleiotropic repressor CodY, ISOLEUCINE | | Authors: | Wilkinson, A.J, Levdikov, V.M, Blagova, E.V. | | Deposit date: | 2016-08-09 | | Release date: | 2017-01-11 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the Branched-chain Amino Acid and GTP-sensing Global Regulator, CodY, from Bacillus subtilis.
J. Biol. Chem., 292, 2017
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5LOJ
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5LNH
 | | Structure of full length Unliganded CodY from Bacillus subtilis | | Descriptor: | GTP-sensing transcriptional pleiotropic repressor CodY, SULFATE ION | | Authors: | Wilkinson, A.J, Levdikov, V.M, Blagova, E.V. | | Deposit date: | 2016-08-04 | | Release date: | 2017-01-11 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structure of the Branched-chain Amino Acid and GTP-sensing Global Regulator, CodY, from Bacillus subtilis.
J. Biol. Chem., 292, 2017
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5LOO
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2GX5
 | | N-terminal GAF domain of transcriptional pleiotropic repressor CodY | | Descriptor: | CYCLIC GUANOSINE MONOPHOSPHATE, GLYCEROL, GTP-sensing transcriptional pleiotropic repressor codY, ... | | Authors: | Wilkinson, A.J, Levdikov, V.M, Blagova, E.V. | | Deposit date: | 2006-05-08 | | Release date: | 2007-04-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | The structure of CodY, a GTP- and isoleucine-responsive regulator of stationary phase and virulence in gram-positive bacteria.
J.Biol.Chem., 281, 2006
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2HGV
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8BPT
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2FYI
 | | Crystal Structure of the Cofactor-Binding Domain of the Cbl Transcriptional Regulator | | Descriptor: | HTH-type transcriptional regulator cbl | | Authors: | Stec, E, Neumann, P, Wilkinson, A.J, Brzozowski, A.M, Bujacz, G.D. | | Deposit date: | 2006-02-08 | | Release date: | 2006-02-21 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | Structural Basis of the Sulphate Starvation Response in E. coli: Crystal Structure and Mutational Analysis of the Cofactor-binding Domain of the Cbl Transcriptional Regulator.
J.Mol.Biol., 364, 2006
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2TGF
 | | THE SOLUTION STRUCTURE OF HUMAN TRANSFORMING GROWTH FACTOR ALPHA | | Descriptor: | TRANSFORMING GROWTH FACTOR-ALPHA | | Authors: | Harvey, T.S, Wilkinson, A.J, Tappin, M.J, Cooke, R.M, Campbell, I.D. | | Deposit date: | 1991-01-23 | | Release date: | 1993-04-15 | | Last modified: | 2017-11-29 | | Method: | SOLUTION NMR | | Cite: | The solution structure of human transforming growth factor alpha.
Eur.J.Biochem., 198, 1991
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1XE3
 | | Crystal Structure of purine nucleoside phosphorylase DeoD from Bacillus anthracis | | Descriptor: | CHLORIDE ION, purine nucleoside phosphorylase | | Authors: | Grenha, R, Levdikov, V.M, Fogg, M, Blagova, E.V, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S, Structural Proteomics in Europe (SPINE) | | Deposit date: | 2004-09-09 | | Release date: | 2004-10-26 | | Last modified: | 2023-08-23 | | Method: | X-RAY DIFFRACTION (2.24 Å) | | Cite: | Structure of purine nucleoside phosphorylase (DeoD) from Bacillus anthracis.
Acta Crystallogr.,Sect.F, 61, 2005
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4UFW
 | | Plasmodium vivax N-myristoyltransferase in complex with a pyridyl inhibitor (compound 22) | | Descriptor: | 2-oxopentadecyl-CoA, 4-chloranyl-N-[2-(3-methoxyphenyl)ethanimidoyl]-2-piperidin-4-yloxy-benzamide, CHLORIDE ION, ... | | Authors: | Yu, Z, Brannigan, J.A, Rangachari, K, Heal, W.P, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | | Deposit date: | 2015-03-19 | | Release date: | 2016-02-03 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Discovery of Pyridyl-Based Inhibitors of Plasmodium Falciparum N-Myristoyltransferase
Medchemcomm, 6, 2015
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4UFX
 | | Plasmodium vivax N-myristoyltransferase in complex with a pyridyl inhibitor (compound 19) | | Descriptor: | 2-oxopentadecyl-CoA, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | Authors: | Yu, Z, Brannigan, J.A, Rangachari, K, Heal, W.P, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | | Deposit date: | 2015-03-19 | | Release date: | 2016-02-03 | | Last modified: | 2024-05-08 | | Method: | X-RAY DIFFRACTION (1.49 Å) | | Cite: | Discovery of Pyridyl-Based Inhibitors of Plasmodium Falciparum N-Myristoyltransferase
Medchemcomm, 6, 2015
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4UFV
 | | Plasmodium vivax N-myristoyltransferase in complex with a pyridyl inhibitor (compound 18) | | Descriptor: | 2-oxopentadecyl-CoA, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | Authors: | Yu, Z, Brannigan, J.A, Rangachari, K, Heal, W.P, Wilkinson, A.J, Holder, A.A, Tate, E.W, Leatherbarrow, R.J. | | Deposit date: | 2015-03-19 | | Release date: | 2016-02-03 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Discovery of Pyridyl-Based Inhibitors of Plasmodium Falciparum N-Myristoyltransferase
Medchemcomm, 6, 2015
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5AEO
 | | Virulence-associated protein VapG from the intracellular pathogen Rhodococcus equi | | Descriptor: | POTASSIUM ION, R. EQUI VAPG PROTEIN | | Authors: | Okoko, T, Blagova, E.V, Whittingham, J.L, Dover, L.G, Wilkinson, A.J. | | Deposit date: | 2015-01-07 | | Release date: | 2015-03-25 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural Characterisation of the Virulence-Associated Protein Vapg from the Horse Pathogen Rhodococcus Equi.
Vet.Microbiol., 179, 2015
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2OLB
 | | OLIGOPEPTIDE BINDING PROTEIN (OPPA) COMPLEXED WITH TRI-LYSINE | | Descriptor: | ACETATE ION, OLIGO-PEPTIDE BINDING PROTEIN, TRIPEPTIDE LYS-LYS-LYS, ... | | Authors: | Tame, J, Wilkinson, A.J. | | Deposit date: | 1995-09-10 | | Release date: | 1996-01-29 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | The crystal structures of the oligopeptide-binding protein OppA complexed with tripeptide and tetrapeptide ligands.
Structure, 3, 1995
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6TAA
 | | STRUCTURE AND MOLECULAR MODEL REFINEMENT OF ASPERGILLUS ORYZAE (TAKA) ALPHA-AMYLASE: AN APPLICATION OF THE SIMULATED-ANNEALING METHOD | | Descriptor: | ALPHA-AMYLASE, CALCIUM ION | | Authors: | Swift, H.J, Brady, L, Derewenda, Z.S, Dodson, E.J, Turkenburg, J.P, Wilkinson, A.J. | | Deposit date: | 1992-08-21 | | Release date: | 1993-10-31 | | Last modified: | 2024-06-05 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structure and molecular model refinement of Aspergillus oryzae (TAKA) alpha-amylase: an application of the simulated-annealing method.
Acta Crystallogr.,Sect.B, 47, 1991
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3O6Q
 | | The Structure of SpoIISA and SpoIISB, a Toxin - Antitoxin System | | Descriptor: | Stage II sporulation protein SA, Stage II sporulation protein SB | | Authors: | Levdikov, V.M, Blagova, E.V, Lebedev, A.A, Wilkinson, A.J, Florek, P, Barak, I. | | Deposit date: | 2010-07-29 | | Release date: | 2010-12-08 | | Last modified: | 2011-07-13 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | The structure and interactions of SpoIISA and SpoIISB, a toxin-antitoxin system in Bacillus subtilis.
J.Biol.Chem., 161, 2010
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3O9P
 | | The structure of the Escherichia coli murein tripeptide binding protein MppA | | Descriptor: | L-ALA-GAMMA-D-GLU-MESO-DIAMINOPIMELIC ACID, Periplasmic murein peptide-binding protein, ZINC ION | | Authors: | Maqbool, A, Levdikov, V.M, Blagova, E.V, Wilkinson, A.J, Thomas, G.H. | | Deposit date: | 2010-08-04 | | Release date: | 2011-07-06 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Compensating Stereochemical Changes Allow Murein Tripeptide to Be Accommodated in a Conventional Peptide-binding Protein.
J.Biol.Chem., 286, 2011
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7ATR
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6ZM3
 | | The structure of an E2 ubiquitin-conjugating complex (UBC2-UEV1) essential for Leishmania amastigote differentiation | | Descriptor: | Putative ubiquitin-conjugating enzyme e2, Ubiquitin-conjugating enzyme-like protein | | Authors: | Burge, R.J, Dodson, E.J, Wilkinson, A.J, Mottram, J.C. | | Deposit date: | 2020-07-01 | | Release date: | 2020-07-22 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex.
Plos Pathog., 16, 2020
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3DD6
 | | Crystal structure of Rph, an exoribonuclease from Bacillus anthracis at 1.7 A resolution | | Descriptor: | Ribonuclease PH, SULFATE ION | | Authors: | Rawlings, A.E, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Wilson, K.S, Wilkinson, A.J, Structural Proteomics in Europe 2 (SPINE-2) | | Deposit date: | 2008-06-05 | | Release date: | 2009-02-10 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.702 Å) | | Cite: | The structure of Rph, an exoribonuclease from Bacillus anthracis, at 1.7 A resolution.
Acta Crystallogr.,Sect.F, 65, 2009
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2PFM
 | | Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis | | Descriptor: | Adenylosuccinate lyase, MALONATE ION | | Authors: | Levdikov, V.M, Blagova, E.V, Baumgart, M, Moroz, O.V, Wilkinson, A.J, Wilson, K.S. | | Deposit date: | 2007-04-05 | | Release date: | 2007-04-17 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis
To be Published
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1YCB
 | | DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY | | Descriptor: | MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R. | | Deposit date: | 1993-08-10 | | Release date: | 1994-01-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
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1YCA
 | | DISTAL POCKET POLARITY IN LIGAND BINDING TO MYOGLOBIN: DEOXY AND CARBONMONOXY FORMS OF A THREONINE68 (E11) MUTANT INVESTIGATED BY X-RAY CRYSTALLOGRAPHY AND INFRARED SPECTROSCOPY | | Descriptor: | CARBON MONOXIDE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE | | Authors: | Cameron, A.D, Smerdon, S.J, Wilkinson, A.J, Habash, J, Helliwell, J.R. | | Deposit date: | 1993-08-10 | | Release date: | 1994-01-31 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Distal pocket polarity in ligand binding to myoglobin: deoxy and carbonmonoxy forms of a threonine68(E11) mutant investigated by X-ray crystallography and infrared spectroscopy.
Biochemistry, 32, 1993
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1QKA
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