6ZM3

The structure of an E2 ubiquitin-conjugating complex (UBC2-UEV1) essential for Leishmania amastigote differentiation

This is a non-PDB format compatible entry.

Summary for 6ZM3

• Entry DOI: 10.2210/pdb6zm3/pdb
• Descriptor: Putative ubiquitin-conjugating enzyme e2, Ubiquitin-conjugating enzyme-like protein (3 entities in total)
• Functional Keywords: leishmaniasis, differentiation, ubiquitin, conjugation, ubc2-uev1 complex, signaling protein
• Biological source: Leishmania mexicana (strain MHOM/GT/2001/U1103); More
• Total number of polymer chains: 4
• Total formula weight: 67155.03

Authors

Burge, R.J.,Dodson, E.J.,Wilkinson, A.J.,Mottram, J.C. (deposition date: 2020-07-01, release date: 2020-07-22, Last modification date: 2024-01-31)

• Primary citation: Burge, R.J.,Damianou, A.,Wilkinson, A.J.,Rodenko, B.,Mottram, J.C.; Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex.; Plos Pathog., 16:e1008784-e1008784, 2020; PubMed: 33108402; DOI: 10.1371/journal.ppat.1008784

Experimental method

X-RAY DIFFRACTION (1.7 Å)