8BPT
Crystal structure of the second bromodomain of BRD5 from Leishmania donovani
Summary for 8BPT
| Entry DOI | 10.2210/pdb8bpt/pdb |
| Descriptor | Bromo domain-containing protein (2 entities in total) |
| Functional Keywords | leishmaniasis, general transcription, lysine acetylation, transcription |
| Biological source | Leishmania donovani BPK282A1 |
| Total number of polymer chains | 2 |
| Total formula weight | 31659.94 |
| Authors | Wilkinson, A.J.,Dodson, E.J.,Jones, N.G.,Borgia, J. (deposition date: 2022-11-17, release date: 2023-09-27, Last modification date: 2023-11-22) |
| Primary citation | Russell, C.N.,Carter, J.L.,Borgia, J.M.,Bush, J.,Calderon, F.,Gabarro, R.,Conway, S.J.,Mottram, J.C.,Wilkinson, A.J.,Jones, N.G. Bromodomain Factor 5 as a Target for Antileishmanial Drug Discovery. Acs Infect Dis., 9:2340-2357, 2023 Cited by PubMed: 37906637DOI: 10.1021/acsinfecdis.3c00431 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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