1NDD
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![BU of 1ndd by Molmil](/molmil-images/mine/1ndd) | STRUCTURE OF NEDD8 | 分子名称: | CHLORIDE ION, PROTEIN (UBIQUITIN-LIKE PROTEIN NEDD8), SULFATE ION | 著者 | Whitby, F.G, Xia, G, Pickart, C.M, Hill, C.P. | 登録日 | 1998-08-21 | 公開日 | 1999-02-23 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Crystal structure of the human ubiquitin-like protein NEDD8 and interactions with ubiquitin pathway enzymes. J.Biol.Chem., 273, 1998
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1FNT
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![BU of 1fnt by Molmil](/molmil-images/mine/1fnt) | CRYSTAL STRUCTURE OF THE 20S PROTEASOME FROM YEAST IN COMPLEX WITH THE PROTEASOME ACTIVATOR PA26 FROM TRYPANOSOME BRUCEI AT 3.2 ANGSTROMS RESOLUTION | 分子名称: | MAGNESIUM ION, PROTEASOME ACTIVATOR PROTEIN PA26, PROTEASOME COMPONENT C1, ... | 著者 | Whitby, F.G, Masters, E, Kramer, L, Knowlton, J.R, Yao, Y, Wang, C.C, Hill, C.P. | 登録日 | 2000-08-23 | 公開日 | 2001-04-11 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for the activation of 20S proteasomes by 11S regulators. Nature, 408, 2000
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1C1G
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![BU of 1c1g by Molmil](/molmil-images/mine/1c1g) | |
7S49
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![BU of 7s49 by Molmil](/molmil-images/mine/7s49) | Crystal Structure of Inhibitor-bound Galactokinase | 分子名称: | (4R)-2-[(1,3-benzoxazol-2-yl)amino]-4-(4-chloro-1H-pyrazol-5-yl)-4,6,7,8-tetrahydroquinazolin-5(1H)-one, Galactokinase, PHOSPHATE ION, ... | 著者 | Whitby, F.G. | 登録日 | 2021-09-08 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
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7S4C
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![BU of 7s4c by Molmil](/molmil-images/mine/7s4c) | Crystal Structure of Inhibitor-bound Galactokinase | 分子名称: | 2-({(4R)-4-(2-chlorophenyl)-2-[(6-fluoro-1,3-benzoxazol-2-yl)amino]-6-methyl-1,4-dihydropyrimidine-5-carbonyl}amino)pyridine-4-carboxylic acid, Galactokinase, PHOSPHATE ION, ... | 著者 | Whitby, F.G. | 登録日 | 2021-09-08 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
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8V14
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![BU of 8v14 by Molmil](/molmil-images/mine/8v14) | Structure of NRAP-1 and its role in NMDAR signaling | 分子名称: | CALCIUM ION, NMDA receptor auxiliary protein | 著者 | Whitby, F.G, Goodell, D.J, Maricq, A.V, Hill, C.P. | 登録日 | 2023-11-19 | 公開日 | 2024-01-31 | 最終更新日 | 2024-08-21 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Mechanistic and structural studies reveal NRAP-1-dependent coincident activation of NMDARs. Cell Rep, 43, 2024
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7RCL
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7RCM
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![BU of 7rcm by Molmil](/molmil-images/mine/7rcm) | Crystal Structure of ADP-bound Galactokinase | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, Galactokinase, ... | 著者 | Whitby, F.G. | 登録日 | 2021-07-07 | 公開日 | 2021-09-29 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure-Based Optimization of Small Molecule Human Galactokinase Inhibitors. J.Med.Chem., 64, 2021
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1AK5
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5ILS
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![BU of 5ils by Molmil](/molmil-images/mine/5ils) | Autoinhibited ETV1 | 分子名称: | ETS translocation variant 1 | 著者 | Whitby, F.G, Currie, S.L. | 登録日 | 2016-03-04 | 公開日 | 2017-02-22 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.399 Å) | 主引用文献 | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
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5ILV
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![BU of 5ilv by Molmil](/molmil-images/mine/5ilv) | Uninhibited ETV5 | 分子名称: | ETS translocation variant 5 | 著者 | Whitby, F.G, Currie, S.L. | 登録日 | 2016-03-04 | 公開日 | 2017-02-22 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
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5ILU
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![BU of 5ilu by Molmil](/molmil-images/mine/5ilu) | Autoinhibited ETV4 | 分子名称: | ETS translocation variant 4 | 著者 | Whitby, F.G, Currie, S.L. | 登録日 | 2016-03-04 | 公開日 | 2017-02-22 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (1.101 Å) | 主引用文献 | Structured and disordered regions cooperatively mediate DNA-binding autoinhibition of ETS factors ETV1, ETV4 and ETV5. Nucleic Acids Res., 45, 2017
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1LC3
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![BU of 1lc3 by Molmil](/molmil-images/mine/1lc3) | Crystal Structure of a Biliverdin Reductase Enzyme-Cofactor Complex | 分子名称: | Biliverdin Reductase A, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION | 著者 | Whitby, F.G, Phillips, J.D, Hill, C.P, McCoubrey, W, Maines, M.D. | 登録日 | 2002-04-05 | 公開日 | 2002-07-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex. J.Mol.Biol., 319, 2002
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1LC0
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![BU of 1lc0 by Molmil](/molmil-images/mine/1lc0) | Structure of Biliverdin Reductase and the Enzyme-NADH Complex | 分子名称: | Biliverdin Reductase A, PHOSPHATE ION | 著者 | Whitby, F.G, Phillips, J.D, Hill, C.P, McCoubrey, W, Maines, M.D. | 登録日 | 2002-04-04 | 公開日 | 2002-07-17 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | 主引用文献 | Crystal structure of a biliverdin IXalpha reductase enzyme-cofactor complex. J.Mol.Biol., 319, 2002
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1URO
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![BU of 1uro by Molmil](/molmil-images/mine/1uro) | UROPORPHYRINOGEN DECARBOXYLASE | 分子名称: | BETA-MERCAPTOETHANOL, PROTEIN (UROPORPHYRINOGEN DECARBOXYLASE) | 著者 | Whitby, F.G, Phillips, J.D, Kushner, J.P, Hill, C.P. | 登録日 | 1998-08-21 | 公開日 | 1998-08-26 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of human uroporphyrinogen decarboxylase. EMBO J., 17, 1998
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4V7O
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![BU of 4v7o by Molmil](/molmil-images/mine/4v7o) | Proteasome Activator Complex | 分子名称: | Proteasome activator BLM10, Proteasome component C1, Proteasome component C11, ... | 著者 | Hill, C.P, Whitby, F.G. | 登録日 | 2009-12-22 | 公開日 | 2014-07-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.005 Å) | 主引用文献 | Structure of a Blm10 complex reveals common mechanisms for proteasome binding and gate opening. Mol.Cell, 37, 2010
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6PSA
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![BU of 6psa by Molmil](/molmil-images/mine/6psa) | PIE12 D-PEPTIDE AGAINST HIV ENTRY (IN COMPLEX WITH IQN17 Q577R RESISTANCE MUTANT) | 分子名称: | CHLORIDE ION, IQN17, PIE12 D-peptide | 著者 | Hill, C.P, Whitby, F.G, Kay, M, Weinstock, M. | 登録日 | 2019-07-12 | 公開日 | 2020-02-05 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Characterization of resistance to a potent D-peptide HIV entry inhibitor. Retrovirology, 16, 2019
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2HTH
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![BU of 2hth by Molmil](/molmil-images/mine/2hth) | Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain | 分子名称: | Ubiquitin, Vacuolar protein sorting protein 36 | 著者 | Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I. | 登録日 | 2006-07-25 | 公開日 | 2006-10-24 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat.Struct.Mol.Biol., 13, 2006
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4R0R
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![BU of 4r0r by Molmil](/molmil-images/mine/4r0r) | Ebolavirus GP Prehairpin Intermediate Mimic | 分子名称: | eboIZN21 | 著者 | Clinton, T.R, Weinstock, M.T, Jacobsen, M.T, Szabo-Fresnais, N, Pandya, M.J, Whitby, F.G, Herbert, A.S, Prugar, L.I, McKinnon, R, Hill, C.P, Welch, B.D, Dye, J.M, Eckert, D.M, Kay, M.S. | 登録日 | 2014-08-01 | 公開日 | 2014-10-22 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | Design and characterization of ebolavirus GP prehairpin intermediate mimics as drug targets. Protein Sci., 24, 2015
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3C3R
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![BU of 3c3r by Molmil](/molmil-images/mine/3c3r) | ALIX BRO1 CHMP4C complex | 分子名称: | Charged multivesicular body protein 4c peptide, GLYCEROL, Programmed cell death 6-interacting protein | 著者 | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | 登録日 | 2008-01-28 | 公開日 | 2008-06-10 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2.02 Å) | 主引用文献 | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3C3O
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![BU of 3c3o by Molmil](/molmil-images/mine/3c3o) | ALIX Bro1-domain:CHMIP4A co-crystal structure | 分子名称: | Charged multivesicular body protein 4a peptide, GLYCEROL, Programmed cell death 6-interacting protein | 著者 | McCullough, J.B, Fisher, R.D, Whitby, F.G, Sundquist, W.I, Hill, C.P. | 登録日 | 2008-01-28 | 公開日 | 2008-06-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | 主引用文献 | ALIX-CHMP4 interactions in the human ESCRT pathway. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3L35
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![BU of 3l35 by Molmil](/molmil-images/mine/3l35) | PIE12 D-peptide against HIV entry | 分子名称: | GP41 N-PEPTIDE, HIV ENTRY INHIBITOR PIE12 | 著者 | Welch, B.D, Redman, J.S, Paul, S, Whitby, F.G, Weinstock, M.T, Reeves, J.D, Lie, Y.S, Eckert, D.M, Hill, C.P, Root, M.J, Kay, M.S. | 登録日 | 2009-12-16 | 公開日 | 2010-11-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance. J.Virol., 84, 2010
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3L36
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![BU of 3l36 by Molmil](/molmil-images/mine/3l36) | PIE12 D-peptide against HIV entry | 分子名称: | 3-CYCLOHEXYL-1-PROPYLSULFONIC ACID, GP41 N-PEPTIDE, HIV ENTRY INHIBITOR PIE12 | 著者 | Welch, B.D, Redman, J.S, Paul, S, Whitby, F.G, Weinstock, M.T, Reeves, J.D, Lie, Y.S, Eckert, D.M, Hill, C.P, Root, M.J, Kay, M.S. | 登録日 | 2009-12-16 | 公開日 | 2010-11-03 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Design of a potent D-peptide HIV-1 entry inhibitor with a strong barrier to resistance. J.Virol., 84, 2010
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8UC6
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![BU of 8uc6 by Molmil](/molmil-images/mine/8uc6) | Calpain-7:IST1 Complex | 分子名称: | Calpain-7, IST1 homolog | 著者 | Paine, E, Whitby, F.G, Hill, C.P, Sunquist, W.I. | 登録日 | 2023-09-25 | 公開日 | 2023-10-25 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.701 Å) | 主引用文献 | The Calpain-7 protease functions together with the ESCRT-III protein IST1 within the midbody to regulate the timing and completion of abscission. Elife, 12, 2023
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7JX4
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![BU of 7jx4 by Molmil](/molmil-images/mine/7jx4) | Crystal Structure of N-Lysine Peptoid-modified Collagen Triple Helix | 分子名称: | Collagen mimetic peptide with N-Lysine guest | 著者 | Yu, M.S, Whitby, F.G, Hill, C.P, Kessler, J.L, Yang, L.D. | 登録日 | 2020-08-26 | 公開日 | 2021-07-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (0.95 Å) | 主引用文献 | Peptoid Residues Make Diverse, Hyperstable Collagen Triple-Helices. J.Am.Chem.Soc., 143, 2021
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