2NW0
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![BU of 2nw0 by Molmil](/molmil-images/mine/2nw0) | Crystal structure of a lysin | Descriptor: | ACETATE ION, PlyB | Authors: | Porter, C.J, Buckle, A.M, Whisstock, J.C. | Deposit date: | 2006-11-14 | Release date: | 2006-12-05 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The 1.6 A Crystal Structure of the Catalytic Domain of PlyB, a Bacteriophage Lysin Active Against Bacillus anthracis. J.Mol.Biol., 366, 2007
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2PEE
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![BU of 2pee by Molmil](/molmil-images/mine/2pee) | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State | Descriptor: | GLYCEROL, SULFATE ION, Serine protease inhibitor | Authors: | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | Deposit date: | 2007-04-02 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | The N terminus of the serpin, tengpin, functions to trap the metastable native state. Embo Rep., 8, 2007
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2OKK
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![BU of 2okk by Molmil](/molmil-images/mine/2okk) | The X-ray crystal structure of the 65kDa isoform of Glutamic Acid Decarboxylase (GAD65) | Descriptor: | GAMMA-AMINO-BUTANOIC ACID, GLYCEROL, Glutamate decarboxylase 2 | Authors: | Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C. | Deposit date: | 2007-01-17 | Release date: | 2007-03-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nat.Struct.Mol.Biol., 14, 2007
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2OKJ
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![BU of 2okj by Molmil](/molmil-images/mine/2okj) | The X-ray crystal structure of the 67kDa isoform of Glutamic Acid Decarboxylase (GAD67) | Descriptor: | 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]BUTANOIC ACID, GAMMA-AMINO-BUTANOIC ACID, Glutamate decarboxylase 1 | Authors: | Buckle, A.M, Fenalti, G, Law, R.H.P, Whisstock, J.C. | Deposit date: | 2007-01-17 | Release date: | 2007-03-27 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop. Nat.Struct.Mol.Biol., 14, 2007
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2PEF
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![BU of 2pef by Molmil](/molmil-images/mine/2pef) | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State | Descriptor: | Serine protease inhibitor | Authors: | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | Deposit date: | 2007-04-03 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The N terminus of the serpin, tengpin, functions to trap the metastable native state. Embo Rep., 8, 2007
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5UGG
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![BU of 5ugg by Molmil](/molmil-images/mine/5ugg) | Protease Inhibitor | Descriptor: | Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(quinolin-2-yl)methyl]-L-tyrosinamide, Plasminogen | Authors: | Law, R.H.P, Wu, G, Whisstock, J.C. | Deposit date: | 2017-01-08 | Release date: | 2017-05-31 | Last modified: | 2020-01-08 | Method: | X-RAY DIFFRACTION (1.2 Å) | Cite: | X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. Blood Adv, 1, 2017
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5UG7
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![BU of 5ug7 by Molmil](/molmil-images/mine/5ug7) | Calcium bound Perforin C2 Domain - T431D | Descriptor: | CALCIUM ION, Perforin-1 | Authors: | Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. | Deposit date: | 2017-01-07 | Release date: | 2018-02-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25, 2018
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5UG6
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![BU of 5ug6 by Molmil](/molmil-images/mine/5ug6) | Perforin C2 Domain - T431D | Descriptor: | IODIDE ION, Perforin-1 | Authors: | Law, R.H.P, Conroy, P.J, Voskoboinik, I, Whisstock, J.C. | Deposit date: | 2017-01-07 | Release date: | 2018-02-07 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Perforin proteostasis is regulated through its C2 domain: supra-physiological cell death mediated by T431D-perforin. Cell Death Differ., 25, 2018
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5UBM
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![BU of 5ubm by Molmil](/molmil-images/mine/5ubm) | Crystal structure of human C1s in complex with inhibitor gigastasin | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C1s subcomponent, Gigastasin | Authors: | Pang, S.S, Whisstock, J.C. | Deposit date: | 2016-12-20 | Release date: | 2017-11-08 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The Structural Basis for Complement Inhibition by Gigastasin, a Protease Inhibitor from the Giant Amazon Leech. J. Immunol., 199, 2017
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5UGD
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![BU of 5ugd by Molmil](/molmil-images/mine/5ugd) | Protease Inhibitor | Descriptor: | Nalpha-[trans-4-(aminomethyl)cyclohexane-1-carbonyl]-N-octyl-O-[(pyridin-4-yl)methyl]-L-tyrosinamide, Plasminogen | Authors: | Law, R.H.P, Wu, G, Whisstock, J.C. | Deposit date: | 2017-01-08 | Release date: | 2017-05-31 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.38 Å) | Cite: | X-ray crystal structure of plasmin with tranexamic acid-derived active site inhibitors. Blood Adv, 1, 2017
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3TI9
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![BU of 3ti9 by Molmil](/molmil-images/mine/3ti9) | Crystal structure of the basic protease BprB from the ovine footrot pathogen, Dichelobacter nodosus | Descriptor: | CALCIUM ION, CHLORIDE ION, GLYCEROL, ... | Authors: | Wong, W, Whisstock, J.C, Porter, C.J. | Deposit date: | 2011-08-20 | Release date: | 2011-10-19 | Last modified: | 2018-01-24 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | S1 Pocket of a Bacterially Derived Subtilisin-like Protease Underpins Effective Tissue Destruction. J.Biol.Chem., 286, 2011
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3UB1
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![BU of 3ub1 by Molmil](/molmil-images/mine/3ub1) | Ntf2 like protein involved in plasmid conjugation | Descriptor: | DI(HYDROXYETHYL)ETHER, ORF13-like protein | Authors: | Porter, C.J, Rosado, C.J, Bantwal, R, Bannam, T.L, Rood, J.I, Whisstock, J.C. | Deposit date: | 2011-10-22 | Release date: | 2012-02-08 | Last modified: | 2012-02-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The conjugation protein TcpC from Clostridium perfringens is structurally related to the type IV secretion system protein VirB8 from Gram-negative bacteria. Mol.Microbiol., 83, 2012
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3TI7
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![BU of 3ti7 by Molmil](/molmil-images/mine/3ti7) | |