1XGL
 
 | | HUMAN INSULIN DISULFIDE ISOMER, NMR, 10 STRUCTURES | | 分子名称: | INSULIN | | 著者 | Hua, Q.X, Gozani, S.N, Chance, R.E, Hoffmann, J.A, Frank, B.H, Weiss, M.A. | | 登録日 | 1996-10-10 | | 公開日 | 1997-04-01 | | 最終更新日 | 2024-10-30 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Structure of a protein in a kinetic trap.
Nat.Struct.Biol., 2, 1995
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1W0D
 | | The high resolution structure of Mycobacterium tuberculosis LeuB (Rv2995c) | | 分子名称: | 3-ISOPROPYLMALATE DEHYDROGENASE, SULFATE ION | | 著者 | Singh, R.K, Kefala, G, Janowski, R, Mueller-Dieckmann, C, Weiss, M.S, TB Structural Genomics Consortium (TBSGC) | | 登録日 | 2004-06-03 | | 公開日 | 2004-12-14 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The High Resolution Structure of Leub (Rv2995C) from Mycobacterium Tuberculosis
J.Mol.Biol., 346, 2005
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5M4J
 | | Crystal Structure of Wild-Type Human Prolidase with GlyPro ligand | | 分子名称: | GLYCEROL, GLYCINE, PROLINE, ... | | 著者 | Wilk, P, Weiss, M.S, Mueller, U, Dobbek, H. | | 登録日 | 2016-10-18 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Substrate specificity and reaction mechanism of human prolidase.
FEBS J., 284, 2017
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5MBY
 | | Crystal Structure of Arg184Gln mutant of Human Prolidase with Mn ions and GlyPro ligand | | 分子名称: | GLYCEROL, GLYCINE, HYDROXIDE ION, ... | | 著者 | Wilk, P, Piwowarczyk, R, Mueller, U, Dobbek, H, Weiss, M.S. | | 登録日 | 2016-11-09 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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5MBZ
 | | Crystal Structure of Ser202Phe mutant of Human Prolidase with Mn ions and GlyPro ligand | | 分子名称: | CHLORIDE ION, GLYCEROL, GLYCINE, ... | | 著者 | Wilk, P, Mueller, U, Dobbek, H, Weiss, M.S. | | 登録日 | 2016-11-09 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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5MC4
 | | Crystal Structure of Gly448Arg mutant of Human Prolidase with Mn ions and GlyPro ligand | | 分子名称: | GLYCEROL, GLYCINE, HYDROXIDE ION, ... | | 著者 | Wilk, P, Mueller, U, Dobbek, H, Weiss, M.S. | | 登録日 | 2016-11-09 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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5MC0
 | | Crystal Structure of delTyr231 mutant of Human Prolidase with Mn ions and GlyPro ligand | | 分子名称: | CHLORIDE ION, GLYCEROL, GLYCINE, ... | | 著者 | Wilk, P, Mueller, U, Dobbek, H, Weiss, M.S. | | 登録日 | 2016-11-09 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.56 Å) | | 主引用文献 | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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5MC2
 | | Crystal Structure of Gly278Asp mutant of Human Prolidase with Mn ions and GlyPro ligand | | 分子名称: | GLYCEROL, GLYCINE, MANGANESE (II) ION, ... | | 著者 | Wilk, P, Mueller, U, Dobbek, H, Weiss, M.S. | | 登録日 | 2016-11-09 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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5M4L
 | | Crystal Structure of Wild-Type Human Prolidase with Mg ions and LeuPro ligand | | 分子名称: | GLYCEROL, HYDROXIDE ION, LEUCINE, ... | | 著者 | Wilk, P, Weiss, M.S, Mueller, U, Dobbek, H. | | 登録日 | 2016-10-18 | | 公開日 | 2017-07-12 | | 最終更新日 | 2020-04-22 | | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | | 主引用文献 | Substrate specificity and reaction mechanism of human prolidase.
FEBS J., 284, 2017
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5MC1
 | | Crystal Structure of Asp276Asn mutant of Human Prolidase with Mn ions and GlyPro ligand | | 分子名称: | GLYCEROL, GLYCINE, MANGANESE (II) ION, ... | | 著者 | Wilk, P, Mueller, U, Dobbek, H, Weiss, M.S. | | 登録日 | 2016-11-09 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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5M4Q
 | | Crystal Structure of Wild-Type Human Prolidase with Mn ions and Pro ligand | | 分子名称: | GLYCEROL, HYDROXIDE ION, MANGANESE (II) ION, ... | | 著者 | Wilk, P, Weiss, M.S, Mueller, U, Dobbek, H. | | 登録日 | 2016-10-18 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | | 主引用文献 | Substrate specificity and reaction mechanism of human prolidase.
FEBS J., 284, 2017
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5M4G
 | | Crystal Structure of Wild-Type Human Prolidase with Mn ions | | 分子名称: | GLYCEROL, HYDROXIDE ION, MANGANESE (II) ION, ... | | 著者 | Wilk, P, Weiss, M.S, Mueller, U, Dobbek, H. | | 登録日 | 2016-10-18 | | 公開日 | 2017-07-12 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Substrate specificity and reaction mechanism of human prolidase.
FEBS J., 284, 2017
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5MC5
 | | Crystal Structure of delGlu452 mutant of Human Prolidase with Mn ions and GlyPro ligand | | 分子名称: | GLYCEROL, GLYCINE, HYDROXIDE ION, ... | | 著者 | Wilk, P, Mueller, U, Dobbek, H, Weiss, M.S. | | 登録日 | 2016-11-09 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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5MC3
 | | Crystal Structure of Glu412Lys mutant of Human Prolidase with Mn ions and GlyPro ligand | | 分子名称: | GLYCEROL, GLYCINE, HYDROXIDE ION, ... | | 著者 | Wilk, P, Mueller, U, Dobbek, H, Weiss, M.S. | | 登録日 | 2016-11-09 | | 公開日 | 2017-12-20 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.52 Å) | | 主引用文献 | Structural basis for prolidase deficiency disease mechanisms.
FEBS J., 285, 2018
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1COI
 | | DESIGNED TRIMERIC COILED COIL-VALD | | 分子名称: | COIL-VALD, SULFATE ION | | 著者 | Ogihara, N.L, Weiss, M.S, Degrado, W.F, Eisenberg, D. | | 登録日 | 1996-08-10 | | 公開日 | 1997-02-12 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The crystal structure of the designed trimeric coiled coil coil-VaLd: implications for engineering crystals and supramolecular assemblies.
Protein Sci., 6, 1997
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2MPI
 | | Solution structure of B24G insulin | | 分子名称: | insulin chain A, insulin chain B | | 著者 | Yang, Y, Wickramasinghe, N.P, Hua, Q, Weiss, M.A. | | 登録日 | 2014-05-19 | | 公開日 | 2014-12-24 | | 最終更新日 | 2023-06-14 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Protective hinge in insulin opens to enable its receptor engagement.
Proc.Natl.Acad.Sci.USA, 111, 2014
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5NHG
 | | Crystal structure of the human dihydrolipoamide dehydrogenase | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dihydrolipoyl dehydrogenase, ... | | 著者 | Szabo, E, Mizsei, R, Wilk, P, Zambo, Z, Torocsik, B, Weiss, M.S, Adam-Vizi, V, Ambrus, A. | | 登録日 | 2017-03-21 | | 公開日 | 2018-05-16 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | | 主引用文献 | Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase.
Free Radic. Biol. Med., 124, 2018
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8OGN
 | | PanDDA analysis group deposition -- CdaA in complex with fragment F2X-Entry A09 | | 分子名称: | Cyclic di-AMP synthase CdaA, MAGNESIUM ION, [1,2]thiazolo[5,4-b]pyridin-3-amine | | 著者 | Garbers, T.B, Neumann, P, Wollenhaupt, J, Weiss, M.S, Ficner, R. | | 登録日 | 2023-03-20 | | 公開日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | | 主引用文献 | CdaA in complex with fragment F2X-Entry A09
To Be Published
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8OGM
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1LPV
 | | DROSOPHILA MELANOGASTER DOUBLESEX (DSX), NMR, 18 STRUCTURES | | 分子名称: | Doublesex protein, ZINC ION | | 著者 | Zhu, L, Wilken, J, Phillips, N, Narendra, U, Chan, G, Stratton, S, Kent, S, Weiss, M.A. | | 登録日 | 2002-05-08 | | 公開日 | 2002-10-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Sexual dimorphism in diverse metazoans is regulated by a novel class of intertwined zinc fingers.
Genes Dev., 14, 2000
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2KQP
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2Q27
 | | Crystal structure of oxalyl-coA decarboxylase from Escherichia coli | | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ... | | 著者 | Werther, T, Zimmer, A, Wille, G, Hubner, G, Weiss, M.S, Konig, S. | | 登録日 | 2007-05-26 | | 公開日 | 2008-06-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | New insights into structure-function relationships of oxalyl CoA decarboxylase from Escherichia coli.
Febs J., 277, 2010
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2KJI
 | | A divergent ins protein in c. elegans structurally resemble insulin and activates the human insulin receptor | | 分子名称: | Probable insulin-like peptide beta-type 5 | | 著者 | Hua, Q.X, Nakarawa, S.H, Wilken, R, Ramos, R.R, Jia, W.H, Bass, J, Weiss, M.A. | | 登録日 | 2009-05-28 | | 公開日 | 2009-06-16 | | 最終更新日 | 2024-10-16 | | 実験手法 | SOLUTION NMR | | 主引用文献 | A divergent INS protein in Caenorhabditis elegans structurally resembles human insulin and activates the human insulin receptor.
Genes Dev., 17, 2003
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4Y4G
 | | Endothiapepsin in complex with fragment B53 | | 分子名称: | ACETATE ION, DIMETHYL SULFOXIDE, Endothiapepsin, ... | | 著者 | Huschmann, F.U, Linnik, J, Weiss, M.S, Mueller, U. | | 登録日 | 2015-02-10 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.439 Å) | | 主引用文献 | Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library.
Acta Crystallogr.,Sect.F, 72, 2016
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4Y3Y
 | | Endothiapepsin in complex with fragment B42 | | 分子名称: | 2-AMINO-4-METHYL-PENTAN-1-OL, ACETATE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Huschmann, F.U, Linnik, J, Weiss, M.S, Mueller, U. | | 登録日 | 2015-02-10 | | 公開日 | 2016-02-17 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.346 Å) | | 主引用文献 | Structures of endothiapepsin-fragment complexes from crystallographic fragment screening using a novel, diverse and affordable 96-compound fragment library.
Acta Crystallogr.,Sect.F, 72, 2016
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