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PDB: 1259 件
3UZD
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BU of 3uzd by Molmil
Crystal structure of 14-3-3 GAMMA
分子名称: 14-3-3 protein gamma, Histone deacetylase 4, MAGNESIUM ION, ...
著者Xu, C, Bian, C, MacKenzie, F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2011-12-07
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V2X
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Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
分子名称: Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2
著者Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2011-12-12
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
2FCF
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BU of 2fcf by Molmil
The crystal structure of the 7th PDZ domain of MPDZ (MUPP-1)
分子名称: Multiple PDZ domain protein
著者Papagrigoriou, E, Berridge, G, Johansson, C, Colebrook, S, Salah, E, Burgess, N, Smee, C, Savitsky, P, Bray, J, Schoch, G, Phillips, C, Gileadi, C, Soundarajan, M, Yang, X, Elkins, J.M, Gorrec, F, Turnbull, A, Edwards, A, Arrowsmith, C, Weigelt, J, Sundstrom, M, Doyle, D.A, Structural Genomics Consortium (SGC)
登録日2005-12-12
公開日2006-01-17
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Structure of PICK1 and other PDZ domains obtained with the help of self-binding C-terminal extensions.
Protein Sci., 16, 2007
2FVV
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BU of 2fvv by Molmil
Human Diphosphoinositol polyphosphate phosphohydrolase 1
分子名称: CHLORIDE ION, Diphosphoinositol polyphosphate phosphohydrolase 1, INOSITOL HEXAKISPHOSPHATE, ...
著者Hallberg, B.M, Kursula, P, Ogg, D, Arrowsmith, C, Berglund, H, Edwards, A, Ehn, M, Flodin, S, Graslund, S, Hammarstrom, M, Hogbom, M, Holmberg-Schiavone, L, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Persson, C, Structural Genomics Consortium (SGC)
登録日2006-01-31
公開日2006-03-11
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Crystal structure of human diphosphoinositol phosphatase 1
Proteins, 77, 2009
2OX0
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BU of 2ox0 by Molmil
Crystal structure of JMJD2A complexed with histone H3 peptide dimethylated at Lys9
分子名称: CHLORIDE ION, JmjC domain-containing histone demethylation protein 3A, N-OXALYLGLYCINE, ...
著者Pilka, E.S, Ng, S.S, Kavanagh, K.L, McDonough, M.A, Savitsky, P, von Delft, F, Arrowsmith, C.H, Weigelt, J, Edwards, A, Sundstrom, M, Schofield, C.J, Oppermann, U, Structural Genomics Consortium (SGC)
登録日2007-02-19
公開日2007-03-13
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity.
Nature, 448, 2007
3V2O
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BU of 3v2o by Molmil
Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
分子名称: Ankyrin repeat family A protein 2, Low-density lipoprotein receptor-related protein 2
著者Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2011-12-12
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3V31
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Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human ANKRA2
分子名称: Ankyrin repeat family A protein 2, CHLORIDE ION, Histone deacetylase 4, ...
著者Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2011-12-12
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
3BOR
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BU of 3bor by Molmil
Crystal structure of the DEADc domain of human translation initiation factor 4A-2
分子名称: Human initiation factor 4A-II
著者Dimov, S, Hong, B, Tempel, W, MacKenzie, F, Karlberg, T, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC)
登録日2007-12-17
公開日2008-01-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Comparative Structural Analysis of Human DEAD-Box RNA Helicases.
Plos One, 5, 2010
2FBN
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BU of 2fbn by Molmil
Plasmodium falciparum putative FK506-binding protein PFL2275c, C-terminal TPR-containing domain
分子名称: 70 kDa peptidylprolyl isomerase, putative
著者Dong, A, Lew, J, Koeieradzki, I, Sundararajan, E, Melone, M, Wasney, G, Zhao, Y, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Bochkarev, A, Hui, R, Hills, T, Structural Genomics Consortium (SGC)
登録日2005-12-09
公開日2006-01-24
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Crystallographic structure of the tetratricopeptide repeat domain of Plasmodium falciparum FKBP35 and its molecular interaction with Hsp90 C-terminal pentapeptide.
Protein Sci., 18, 2009
2RJF
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BU of 2rjf by Molmil
Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 12-30), orthorhombic form I
分子名称: Histone H4, Lethal(3)malignant brain tumor-like protein
著者Allali-Hassani, A, Liu, Y, Herzanych, N, Ouyang, H, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J.R, Structural Genomics Consortium (SGC)
登録日2007-10-14
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献L3MBTL1 recognition of mono- and dimethylated histones.
Nat.Struct.Mol.Biol., 14, 2007
2RJE
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BU of 2rje by Molmil
Crystal structure of L3MBTL1 in complex with H4K20Me2 (residues 17-25), orthorhombic form II
分子名称: CHLORIDE ION, Histone H4, Lethal(3)malignant brain tumor-like protein
著者Allali-Hassani, A, Liu, Y, Herzanych, N, Ouyang, H, Mackenzie, F, Crombet, L, Loppnau, P, Kozieradzki, I, Vedadi, M, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J.R, Structural Genomics Consortium (SGC)
登録日2007-10-14
公開日2007-10-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献L3MBTL1 recognition of mono- and dimethylated histones.
Nat.Struct.Mol.Biol., 14, 2007
2UV2
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BU of 2uv2 by Molmil
Crystal Structure Of Human Ste20-Like Kinase Bound To 4-(4-(5- Cyclopropyl-1H-pyrazol-3-ylamino)-quinazolin-2-ylamino)-phenyl)- acetonitrile
分子名称: 1,2-ETHANEDIOL, STE20-LIKE SERINE-THREONINE KINASE, THIOCYANATE ION, ...
著者Pike, A.C.W, Rellos, P, Fedorov, O, Keates, T, Salah, E, Savitsky, P, Papagrigoriou, E, Bunkoczi, G, Debreczeni, J.E, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Sundstrom, M, Knapp, S.
登録日2007-03-08
公開日2007-03-20
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Activation Segment Dimerization: A Mechanism for Kinase Autophosphorylation of Non-Consensus Sites.
Embo J., 27, 2008
2QGX
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BU of 2qgx by Molmil
Ubiquitin-conjugating enzyme E2Q
分子名称: Ubiquitin-conjugating enzyme E2 Q1
著者Neculai, D, Avvakumov, G.V, Xue, S, Walker, J.R, Mackenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Sicheri, F, Dhe-Paganon, S, Structural Genomics Consortium (SGC)
登録日2007-06-29
公開日2008-03-18
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
Mol Cell Proteomics, 11, 2012
2GJT
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BU of 2gjt by Molmil
Crystal structure of the human receptor phosphatase PTPRO
分子名称: CHLORIDE ION, Receptor-type tyrosine-protein phosphatase PTPRO
著者Barr, A, Ugochukwu, E, Eswaran, J, Das, S, Niesen, F, Savitsky, P, Turnbull, A, Sundstrom, M, Arrowsmith, C, Edwards, A, Weigelt, J, von Delft, F, Papagrigoriou, E, Knapp, S, Structural Genomics Consortium (SGC)
登録日2006-03-31
公開日2006-05-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Large-scale structural analysis of the classical human protein tyrosine phosphatome.
Cell(Cambridge,Mass.), 136, 2009
3TYY
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BU of 3tyy by Molmil
Crystal Structure of Human Lamin-B1 Coil 2 Segment
分子名称: Lamin-B1
著者Lam, R, Xu, C, Bian, C.B, Mackenzie, F, Walker, J.R, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2011-09-26
公開日2011-10-05
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.399 Å)
主引用文献Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1.
Febs Lett., 586, 2012
2B0R
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BU of 2b0r by Molmil
Crystal Structure of Cyclase-Associated Protein from Cryptosporidium parvum
分子名称: UNKNOWN ATOM OR ION, possible adenyl cyclase-associated protein
著者Tempel, W, Dong, A, Zhao, Y, Lew, J, Kozieradzki, I, Alam, Z, Melone, M, Wasney, G, Vedadi, M, Arrowsmith, C, Edwards, A, Weigelt, J, Sundstrom, M, Hui, R, Bochkarev, A, Artz, J, Structural Genomics Consortium (SGC)
登録日2005-09-14
公開日2005-09-27
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and function of a G-actin sequestering protein with a vital role in malaria oocyst development inside the mosquito vector
J.Biol.Chem., 151, 2010
2VAG
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BU of 2vag by Molmil
Crystal structure of di-phosphorylated human CLK1 in complex with a novel substituted indole inhibitor
分子名称: DUAL SPECIFICITY PROTEIN KINASE CLK1, ethyl 3-[(E)-2-amino-1-cyanoethenyl]-6,7-dichloro-1-methyl-1H-indole-2-carboxylate
著者Pike, A.C.W, Bullock, A.N, Fedorov, O, Pilka, E.S, Ugochukwu, E, von Delft, F, Edwards, A, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Huber, K, Bracher, F, Knapp, S.
登録日2007-08-31
公開日2007-10-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Specific Clk Inhibitors from a Novel Chemotype for Regulation of Alternative Splicing.
Chem.Biol, 18, 2011
3UMN
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BU of 3umn by Molmil
Crystal Structure of Lamin-B1
分子名称: Lamin-B1
著者Xu, C, Bian, C.B, Amaya, M.F, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2011-11-14
公開日2011-11-30
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structures of the coil 2B fragment and the globular tail domain of human lamin B1.
Febs Lett., 586, 2012
3FKC
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Crystal Structure of Human Zinc finger and BTB domain containing 33
分子名称: Transcriptional regulator Kaiso
著者Filippakopoulos, P, Bullock, A, Keates, T, Burgess-Brown, N, Muniz, J, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC)
登録日2008-12-16
公開日2008-12-23
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal Structure of Human Zinc finger and BTB domain containing 33
To be Published
3UXG
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Crystal structure of RFXANK
分子名称: DNA-binding protein RFXANK, Histone deacetylase 4, UNKNOWN ATOM OR ION
著者Tempel, W, Chao, X, Bian, C, Li, Y, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Min, J, Structural Genomics Consortium (SGC)
登録日2011-12-05
公開日2012-06-13
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
2VIF
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BU of 2vif by Molmil
Crystal structure of SOCS6 SH2 domain in complex with a c-KIT phosphopeptide
分子名称: 1,2-ETHANEDIOL, MAST/STEM CELL GROWTH FACTOR RECEPTOR, SUPPRESSOR OF CYTOKINE SIGNALLING 6
著者Bullock, A, Pike, A.C.W, Savitsky, P, Keates, T, Pilka, E.S, von Delft, F, Edwards, A, Weigelt, J, Arrowsmith, C.H, Knapp, S.
登録日2007-11-30
公開日2007-12-25
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural Basis for C-Kit Inhibition by the Suppressor of Cytokine Signaling 6 (Socs6) Ubiquitin Ligase.
J.Biol.Chem., 286, 2011
3IHO
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BU of 3iho by Molmil
The C-terminal glycosylase domain of human MBD4
分子名称: Methyl-CpG-binding domain protein 4
著者Amaya, M.F, Xu, C, Bian, C.B, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2009-07-30
公開日2009-08-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献The C-terminal glycosylase domain of human MBD4
To be Published
2I7C
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BU of 2i7c by Molmil
The crystal structure of spermidine synthase from p. falciparum in complex with AdoDATO
分子名称: 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, GLYCEROL, S-ADENOSYL-1,8-DIAMINO-3-THIOOCTANE, ...
著者Qiu, W, Dong, A, Ren, H, Wu, H, Wasney, G, Vedadi, M, Lew, J, Kozieradski, I, Edwards, A.M, Arrowsmith, C.H, Weigelt, J, Sundstrom, M, Plotnikov, A.N, Bochkarev, A, Hui, R, Structural Genomics Consortium (SGC)
登録日2006-08-30
公開日2006-09-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.71 Å)
主引用文献Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO.
J.Mol.Biol., 373, 2007
3V30
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Crystal Structure of the Peptide Bound Complex of the Ankyrin Repeat Domains of Human RFXANK
分子名称: DNA-binding protein RFX5, DNA-binding protein RFXANK
著者Lam, R, Xu, C, Bian, C.B, Kania, J, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Min, J, Structural Genomics Consortium (SGC)
登録日2011-12-12
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.57 Å)
主引用文献Sequence-Specific Recognition of a PxLPxI/L Motif by an Ankyrin Repeat Tumbler Lock.
Sci.Signal., 5, 2012
2HW4
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Crystal structure of human phosphohistidine phosphatase
分子名称: 14 kDa phosphohistidine phosphatase, FORMIC ACID
著者Busam, R.D, Thorsell, A.G, Arrowsmith, C, Berglund, H, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Holmberg Schiavone, L, Hogbom, M, Kotenyova, T, Nilsson-Ehle, P, Nordlund, P, Nyman, T, Ogg, D, Stenmark, P, Sundstrom, M, Uppenberg, J, Van Den Berg, S, Weigelt, J, Persson, C, Hallberg, B.M, Structural Genomics Consortium (SGC)
登録日2006-07-31
公開日2006-08-29
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献First structure of a eukaryotic phosphohistidine phosphatase
J.Biol.Chem., 281, 2006

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