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PDB: 120 件
5Y4F
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BU of 5y4f by Molmil
Crystal Structure of AnkB Ankyrin Repeats R13-24 in complex with autoinhibition segment AI-c
分子名称: ACETATE ION, Ankyrin-2, CALCIUM ION
著者Chen, K, Li, J, Wang, C, Wei, Z, Zhang, M.
登録日2017-08-03
公開日2017-09-13
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.953 Å)
主引用文献Autoinhibition of ankyrin-B/G membrane target bindings by intrinsically disordered segments from the tail regions.
Elife, 6, 2017
6IUH
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BU of 6iuh by Molmil
Crystal structure of GIT1 PBD domain in complex with Liprin-alpha2
分子名称: ARF GTPase-activating protein GIT1, IODIDE ION, Liprin-alpha-2
著者Liang, M, Wei, Z.
登録日2018-11-28
公開日2019-02-20
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics.
J. Biol. Chem., 294, 2019
6IXQ
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BU of 6ixq by Molmil
Structure of Myo2-GTD in complex with Smy1
分子名称: Kinesin-related protein SMY1, Myosin-2
著者Tang, K, Wei, Z.
登録日2018-12-11
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6IXR
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BU of 6ixr by Molmil
Structure of Myo2-GTD in complex with Inp2
分子名称: Inheritance of peroxisomes protein 2, Myosin-2, SULFATE ION
著者Tang, K, Wei, Z.
登録日2018-12-11
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.854 Å)
主引用文献Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6IXO
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BU of 6ixo by Molmil
Apo structure of Myo2-GTD
分子名称: CHLORIDE ION, Myosin-2, SULFATE ION
著者Tang, K, Wei, Z.
登録日2018-12-11
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6IUI
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BU of 6iui by Molmil
Crystal structure of GIT1 PBD domain in complex with Paxillin LD4 motif
分子名称: ARF GTPase-activating protein GIT1, Paxillin
著者Liang, M, Wei, Z.
登録日2018-11-28
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural basis of the target-binding mode of the G protein-coupled receptor kinase-interacting protein in the regulation of focal adhesion dynamics.
J. Biol. Chem., 294, 2019
6IXP
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BU of 6ixp by Molmil
Structure of Myo2-GTD in complex with Mmr1
分子名称: Mitochondrial MYO2 receptor-related protein 1, Myosin-2
著者Tang, K, Wei, Z.
登録日2018-12-11
公開日2019-03-06
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.733 Å)
主引用文献Structural mechanism for versatile cargo recognition by the yeast class V myosin Myo2.
J.Biol.Chem., 294, 2019
6KR4
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BU of 6kr4 by Molmil
Crystal structure of the liprin-alpha3_SAM123/LAR_D1D2 complex
分子名称: HEXAETHYLENE GLYCOL, Liprin-alpha-3, PHOSPHATE ION, ...
著者Xie, X, Liang, M, Luo, L, Wei, Z.
登録日2019-08-20
公開日2020-01-15
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Structural basis of liprin-alpha-promoted LAR-RPTP clustering for modulation of phosphatase activity.
Nat Commun, 11, 2020
7FH7
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BU of 7fh7 by Molmil
Friedel-Crafts alkylation enzyme CylK mutant Y37F
分子名称: 5-[(2S,7R)-7-fluoranyl-2-methyl-undecyl]benzene-1,3-diol, CALCIUM ION, CHLORIDE ION, ...
著者Wang, H.Q, Wei, Z, Xiang, Z.
登録日2021-07-29
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.42 Å)
主引用文献Structural Basis for the Friedel-Crafts Alkylation in Cylindrocyclophane Biosynthesis
ACS Catal., 12, 2022
7FH8
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BU of 7fh8 by Molmil
Friedel-Crafts alkylation enzyme CylK mutant H391A
分子名称: 2-[(5S,10S)-11-[3,5-bis(oxidanyl)phenyl]-10-methyl-undecan-5-yl]-5-[(2S,7R)-7-fluoranyl-2-methyl-undecyl]benzene-1,3-diol, CALCIUM ION, CHLORIDE ION, ...
著者Wang, H.Q, Wei, Z, Xiang, Z.
登録日2021-07-29
公開日2022-02-16
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.32 Å)
主引用文献Structural Basis for the Friedel-Crafts Alkylation in Cylindrocyclophane Biosynthesis
ACS Catal., 12, 2022
5Y7N
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Crystal structure of AKR1B10 in complex with NADP+ and Androst-4-ene-3-beta-6-alpha-diol
分子名称: (3S,6S,8S,9S,10R,13S,14R)-10,13-dimethyl-2,3,6,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,6-diol, Aldo-keto reductase family 1 member B10, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
著者Hong, Z, Liping, Z, Cuiyun, L, Wei, Z.
登録日2017-08-17
公開日2018-08-29
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural determinants for the inhibition of AKR1B10 by steroids
To Be Published
7D2G
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BU of 7d2g by Molmil
Coiled-coil structure of liprin-alpha2_H2delC
分子名称: GLYCEROL, Liprin-alpha-2
著者Liang, M, Wei, Z.
登録日2020-09-16
公開日2021-04-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins.
Cell Rep, 34, 2021
7D2E
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BU of 7d2e by Molmil
Tetrameric coiled-coil structure of liprin-alpha2_H3
分子名称: Liprin-alpha-2
著者Liang, M, Wei, Z.
登録日2020-09-16
公開日2021-04-07
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins.
Cell Rep, 34, 2021
7D2H
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BU of 7d2h by Molmil
Tetrameric coiled-coil structure of liprin-alpha2_H2
分子名称: GLYCEROL, Liprin-alpha-2
著者Liang, M, Wei, Z.
登録日2020-09-16
公開日2021-04-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Oligomerized liprin-alpha promotes phase separation of ELKS for compartmentalization of presynaptic active zone proteins.
Cell Rep, 34, 2021
7D2T
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BU of 7d2t by Molmil
Crystal structure of Rsu1/PINCH1_LIM45C complex
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, ...
著者Yang, H, Wei, Z, Yu, C.
登録日2020-09-17
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
7D2S
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BU of 7d2s by Molmil
Crystal structure of Rsu1/PINCH1_LIM5C complex
分子名称: GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, Ras suppressor protein 1, ...
著者Yang, H, Wei, Z, Cong, Y.
登録日2020-09-17
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.653 Å)
主引用文献Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
7D2U
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BU of 7d2u by Molmil
Crystal structure of Rsu1/PINCH1_LIM45C complex
分子名称: GLYCEROL, LIM and senescent cell antigen-like-containing domain protein 1, MALONATE ION, ...
著者Yang, H, Wei, Z, Cong, Y.
登録日2020-09-17
公開日2021-02-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Complex structures of Rsu1 and PINCH1 reveal a regulatory mechanism of the ILK/PINCH/Parvin complex for F-actin dynamics.
Elife, 10, 2021
7DDX
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BU of 7ddx by Molmil
Crystal structure of KANK1 S1179F mutant in complex wtih eIF4A1
分子名称: Eukaryotic initiation factor 4A-I, GLYCEROL, KN motif and ankyrin repeat domains 1, ...
著者Pan, W, Xu, Y, Wei, Z.
登録日2020-10-30
公開日2021-09-08
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Nephrotic-syndrome-associated mutation of KANK2 induces pathologic binding competition with physiological interactor KIF21A.
J.Biol.Chem., 297, 2021
8CYI
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BU of 8cyi by Molmil
Cryo-EM structures and computational analysis for enhanced potency in MTA-synergic inhibition of human protein arginine methyltransferase 5
分子名称: 5'-DEOXY-5'-METHYLTHIOADENOSINE, Methylosome protein 50, N-[(2-aminoquinolin-7-yl)methyl]-9-(2-hydroxyethyl)-2,3,4,9-tetrahydro-1H-carbazole-6-carboxamide, ...
著者Yadav, G.P, Wei, Z, Xiaozhi, Y, Chenglong, L, Jiang, Q.
登録日2022-05-23
公開日2023-04-12
最終更新日2024-06-12
実験手法ELECTRON MICROSCOPY (3.14 Å)
主引用文献Cryo-EM structure-based selection of computed ligand poses enables design of MTA-synergic PRMT5 inhibitors of better potency.
Commun Biol, 5, 2022
7Y8W
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BU of 7y8w by Molmil
Crystal structure of DLC-1/SAO-1 complex
分子名称: Dynein light chain 1, cytoplasmic, GLYCEROL, ...
著者Yan, H, Zhao, C, Wei, Z, Yu, C.
登録日2022-06-24
公開日2023-07-26
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Interaction between DLC-1 and SAO-1 facilitates CED-4 translocation during apoptosis in the Caenorhabditis elegans germline.
Cell Death Discov, 8, 2022

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件を2024-06-12に公開中

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