7RIG
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![BU of 7rig by Molmil](/molmil-images/mine/7rig) | Structure of ACLY-D1026A-substrates | Descriptor: | (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-07-19 | Release date: | 2023-05-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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7RKZ
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![BU of 7rkz by Molmil](/molmil-images/mine/7rkz) | Structure of ACLY D1026A-substrates-asym-int | Descriptor: | (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-07-22 | Release date: | 2023-05-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.6 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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7RMP
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![BU of 7rmp by Molmil](/molmil-images/mine/7rmp) | Structure of ACLY D1026A - substrates-asym | Descriptor: | (3S)-citryl-Coenzyme A, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-07-28 | Release date: | 2023-05-10 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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7CTV
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![BU of 7ctv by Molmil](/molmil-images/mine/7ctv) | |
7CTX
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![BU of 7ctx by Molmil](/molmil-images/mine/7ctx) | |
6POE
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![BU of 6poe by Molmil](/molmil-images/mine/6poe) | Structure of ACLY in complex with CoA | Descriptor: | ATP-citrate synthase, COENZYME A | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2019-07-03 | Release date: | 2019-12-25 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
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6UIA
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![BU of 6uia by Molmil](/molmil-images/mine/6uia) | |
7SNI
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![BU of 7sni by Molmil](/molmil-images/mine/7sni) | Structure of G6PD-D200N tetramer bound to NADP+ and G6P | Descriptor: | 6-O-phosphono-beta-D-glucopyranose, Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-10-28 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.5 Å) | Cite: | Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SNG
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![BU of 7sng by Molmil](/molmil-images/mine/7sng) | structure of G6PD-WT tetramer | Descriptor: | Glucose-6-phosphate 1-dehydrogenase | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-10-28 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity. Proc.Natl.Acad.Sci.USA, 119, 2022
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7TOE
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![BU of 7toe by Molmil](/molmil-images/mine/7toe) | |
7TOF
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![BU of 7tof by Molmil](/molmil-images/mine/7tof) | Structure of G6PD-WT dimer with no symmetry applied | Descriptor: | Glucose-6-phosphate 1-dehydrogenase | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2022-01-24 | Release date: | 2022-09-14 | Last modified: | 2024-06-12 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SNH
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![BU of 7snh by Molmil](/molmil-images/mine/7snh) | Structure of G6PD-D200N tetramer bound to NADP+ | Descriptor: | Glucose-6-phosphate 1-dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-10-28 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (2.2 Å) | Cite: | Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity. Proc.Natl.Acad.Sci.USA, 119, 2022
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7SNF
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![BU of 7snf by Molmil](/molmil-images/mine/7snf) | Structure of G6PD-WT dimer | Descriptor: | Glucose-6-phosphate 1-dehydrogenase | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2021-10-28 | Release date: | 2022-07-13 | Last modified: | 2024-06-05 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Allosteric role of a structural NADP + molecule in glucose-6-phosphate dehydrogenase activity. Proc.Natl.Acad.Sci.USA, 119, 2022
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7UAL
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![BU of 7ual by Molmil](/molmil-images/mine/7ual) | |
7UC2
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![BU of 7uc2 by Molmil](/molmil-images/mine/7uc2) | |
6POF
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![BU of 6pof by Molmil](/molmil-images/mine/6pof) | Structure of human ATP citrate lyase | Descriptor: | ATP-citrate synthase | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2019-07-03 | Release date: | 2020-01-01 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Molecular basis for acetyl-CoA production by ATP-citrate lyase. Nat.Struct.Mol.Biol., 27, 2020
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6UV5
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![BU of 6uv5 by Molmil](/molmil-images/mine/6uv5) | |
6UUW
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![BU of 6uuw by Molmil](/molmil-images/mine/6uuw) | Structure of human ATP citrate lyase E599Q mutant in complex with Mg2+, citrate, ATP and CoA | Descriptor: | (2S)-2-hydroxy-2-[2-oxo-2-(phosphonooxy)ethyl]butanedioic acid, ADENOSINE-5'-DIPHOSPHATE, ATP-citrate synthase, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2019-11-01 | Release date: | 2019-12-25 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | Molecular basis for acetyl-CoA production by ATP-citrate lyase Nat.Struct.Mol.Biol., 27, 2020
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6UI9
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![BU of 6ui9 by Molmil](/molmil-images/mine/6ui9) | |
8G5D
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![BU of 8g5d by Molmil](/molmil-images/mine/8g5d) | |
8G1F
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![BU of 8g1f by Molmil](/molmil-images/mine/8g1f) | Structure of ACLY-D1026A-products | Descriptor: | (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2023-02-02 | Release date: | 2023-05-10 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.4 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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8G1E
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![BU of 8g1e by Molmil](/molmil-images/mine/8g1e) | Structure of ACLY-D1026A-products-asym | Descriptor: | (3S)-citryl-Coenzyme A, ACETYL COENZYME *A, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Wei, X, Marmorstein, R. | Deposit date: | 2023-02-02 | Release date: | 2023-05-10 | Last modified: | 2024-06-19 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Allosteric role of the citrate synthase homology domain of ATP citrate lyase. Nat Commun, 14, 2023
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8WGV
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![BU of 8wgv by Molmil](/molmil-images/mine/8wgv) | BA.2(S375) Spike (S6P)/hACE2 complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Wei, X, Zhang, Z. | Deposit date: | 2023-09-22 | Release date: | 2024-02-28 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.92 Å) | Cite: | The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis. Nat.Immunol., 25, 2024
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8WGW
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![BU of 8wgw by Molmil](/molmil-images/mine/8wgw) | Local refinement of RBD-ACE2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ... | Authors: | Wei, X, Zhang, Z. | Deposit date: | 2023-09-22 | Release date: | 2024-02-28 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | The receptor binding domain of SARS-CoV-2 Omicron subvariants targets Siglec-9 to decrease its immunogenicity by preventing macrophage phagocytosis. Nat.Immunol., 25, 2024
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7LJ9
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![BU of 7lj9 by Molmil](/molmil-images/mine/7lj9) | |